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  1. 2061
    Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells
    “... is not long lasting and can have systemic effects. Here, the authors utilize a nanocarrier for siRNA...”
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  2. 2062
    Novel use of a chemically modified siRNA for robust and sustainable in vivo gene silencing in the retina
    “... commercially available and chemically modified siRNA so-called Accell siRNA, we established a novel in vivo...”
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  3. 2063
    The long non coding RNA H19 as a biomarker for breast cancer diagnosis in Lebanese women
    “... variations, the levels of the LncRNA H19 were measured in anonymous tissues obtained from 79 women’s image...”
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  4. 2064
    RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning
    “...The limited availability of high-resolution 3D RNA structures for model training limits RNA...”
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  5. 2065
    Inhibition of Circulating Exosomal miRNA-20b-5p Accelerates Diabetic Wound Repair
    por Chen K, Yu T, Wang X
    Publicado 2021
    “... or this miRNA both in vivo and in vitro was sufficient to slow wound repair.Conclusion: Dia-Exos exhibit...”
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  6. 2066
    Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
    “..., however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene...”
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  7. 2067
    The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans
    “... feedback regulators of inflammation in humans. Here, the authors show that the human lncRNA LUCAT1...”
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  8. 2068
    Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice
    “... that changing miRNA biogenesis and leukotriene B4 signaling in mice modulates this switch in the niche....”
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  9. 2069
    Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping
    “...Expression of Cas9 and gRNA from viral vectors in vivo may cause off-target activity. Here...”
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  10. 2070
    RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
    “... of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin...”
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  11. 2071
    Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
    “... mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory...”
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  12. 2072
    Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
    “...Cytosine base editors have been reported to induce off-target mutations in DNA and RNA. Here...”
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  13. 2073
    Circulating miRNA is a useful diagnostic biomarker for nonalcoholic steatohepatitis in nonalcoholic fatty liver disease
    “... the diagnostic value of circulating miRNAs. Small RNA sequencing was performed on 12 NAFL patients and 12 NASH...”
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  14. 2074
    Publisher Correction: MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia
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  15. 2075
    Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases
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  16. 2076
    Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST
    “...Single-cell RNA-seq (scRNA-seq) is being widely used to resolve cellular heterogeneity. Here...”
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  17. 2077
    Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines
    “... the authors show that intronic RNA from the HIV-1 provirus can induce type I interferon and inflammatory...”
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  18. 2078
    Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
    “... infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation...”
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  19. 2079
    XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1
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  20. 2080
    Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma
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