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  1. 1161
    Single-cell, single-mRNA analysis of Ccnb1 promoter regulation
    por Nidhi Vishnoi, Jie Yao
    Publicado 2017
    “... activities at single-mRNA level. mRNA counts, Pol II density and Pol II firing rates of the Ccnb1 promoter...”
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  2. 1162
    Dual extraction of mRNA and lipids from a single biological sample
    “...Abstract The extraction of RNA and lipids from a large number of biological samples is time...”
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  3. 1163
    Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries
    “... improvements, such as modifications to the guide RNA (gRNA) scaffold and the development of gRNA on-target...”
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  4. 1164
    Massive mining of publicly available RNA-seq data from human and mouse
    “...Publicly available RNA-seq data is provided mostly in raw form, resulting in a barrier...”
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  5. 1165
    RNA editing derived epitopes function as cancer antigens to elicit immune responses
    “...RNA editing is a biological process that creates sequence variation. Here the authors show...”
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  6. 1166
    Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia
    “...The RNA binding protein MUSASHI-2 (MSI2) is a potential therapeutic target for acute myeloid...”
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  7. 1167
    Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection
    “..., such as respiratory syncytial virus (RSV). Here, the authors develop an mRNA-based approach to express membrane...”
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  8. 1168
    Single-cell RNA-seq denoising using a deep count autoencoder
    “...Single-cell RNA sequencing is a powerful method to study gene expression, but noise in the data can...”
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  9. 1169
    PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery
    “... regulation and can systematically deliver VEGF siRNA, significantly reducing lung cancer growth in mice....”
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  10. 1170
    A web server for comparative analysis of single-cell RNA-seq data
    “...Publicly available single cell RNA-seq datasets represent valuable resources for comparative...”
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  11. 1171
    Insulin micro-secretion in Type 1 diabetes and related microRNA profiles
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  12. 1172
    Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa
    “... for which there is no current treatment. In this study, the authors use a novel form of RNA-interference...”
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  13. 1173
    Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3
    “... present the cryo-EM structure of a functional Cas12j3−crRNA complex in the post-catalytic state...”
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  14. 1174
    Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing
    “... computational method that can extract detailed immune repertoire information from existing tissue-specific RNA...”
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  15. 1175
    A widespread alternate form of cap-dependent mRNA translation initiation
    “... to promote cap-dependent translation of a significant number of mRNA in an eIF4E-independent manner....”
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  16. 1176
    Global pairwise RNA interaction landscapes reveal core features of protein recognition
    “...RNA–protein interactions often depend on the recognition of extended RNA elements...”
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  17. 1177
    Comprehensive analysis of competitive endogenous RNA associated with immune infiltration in lung adenocarcinoma
    “...Abstract To identify the prognostic biomarker of the competitive endogenous RNA (ceRNA) and explore...”
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  18. 1178
    Sensitive and powerful single-cell RNA sequencing using mcSCRB-seq
    “...Single-cell RNA-barcoding and sequencing is an efficient, genome-wide method to characterize...”
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  19. 1179
    Development of a genetically encodable FRET system using fluorescent RNA aptamers
    “...FRET has been used to study protein conformational changes but has never been applied to RNA...”
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  20. 1180
    Structural and functional analysis of mRNA export regulation by the nuclear pore complex
    “...The export of mRNA to the cytosol depends on the nuclear pore complex (NPC) and the activation...”
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