An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

par Leo Hanke, Laura Vidakovics Perez, Daniel J. Sheward, Hrishikesh Das, Tim Schulte, Ainhoa Moliner-Morro, Martin Corcoran, Adnane Achour, Gunilla B. Karlsson Hedestam, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publié 2020

Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity

par Bettina Weigelin, Annemieke Th. den Boer, Esther Wagena, Kelly Broen, Harry Dolstra, Rob J. de Boer, Carl G. Figdor, Johannes Textor, Peter Friedl
Publié 2021

A comprehensive risk score for effective risk stratification and screening of nasopharyngeal carcinoma

par Xiang Zhou, Su-Mei Cao, Yong-Lin Cai, Xiao Zhang, Shanshan Zhang, Guo-Fei Feng, Yufeng Chen, Qi-Sheng Feng, Yijun Chen, Ellen T. Chang, Zhonghua Liu, Hans-Olov Adami, Jianjun Liu, Weimin Ye, Zhe Zhang, Yi-Xin Zeng, Miao Xu
Publié 2021

Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia

par Reina Bassil, Kenneth Shields, Kevin Granger, Ivan Zein, Shirley Ng, Ben Chih
Publié 2021

Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

par Shubham Khetan, Susan Kales, Romy Kursawe, Alexandria Jillette, Jacob C. Ulirsch, Steven K. Reilly, Duygu Ucar, Ryan Tewhey, Michael L. Stitzel
Publié 2021

Circadian clock mechanism driving mammalian photoperiodism

par S. H. Wood, M. M. Hindle, Y. Mizoro, Y. Cheng, B. R. C. Saer, K. Miedzinska, H. C. Christian, N. Begley, J. McNeilly, A. S. McNeilly, S. L. Meddle, D. W. Burt, A. S. I. Loudon
Publié 2020

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions

par Bei Liu, Honglue Shi, Atul Rangadurai, Felix Nussbaumer, Chia-Chieh Chu, Kevin Andreas Erharter, David A. Case, Christoph Kreutz, Hashim M. Al-Hashimi
Publié 2021

Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination

par Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publié 2020

Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II

par Pabitra K. Parua, Sampada Kalan, Bradley Benjamin, Miriam Sansó, Robert P. Fisher
Publié 2020

Author Correction: Reef Cover, a coral reef classification for global habitat mapping from remote sensing

par Emma V. Kennedy, Chris M. Roelfsema, Mitchell B. Lyons, Eva M. Kovacs, Rodney Borrego-Acevedo, Meredith Roe, Stuart R. Phinn, Kirk Larsen, Nicholas J. Murray, Doddy Yuwono, Jeremy Wolff, Paul Tudman
Publié 2021

CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates

par Hideki Shishido, Jae Seok Yoon, Zhongying Yang, William R. Skach
Publié 2020

Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans

par PingHsun Hsieh, Vy Dang, Mitchell R. Vollger, Yafei Mao, Tzu-Hsueh Huang, Philip C. Dishuck, Carl Baker, Stuart Cantsilieris, Alexandra P. Lewis, Katherine M. Munson, Melanie Sorensen, AnneMarie E. Welch, Jason G. Underwood, Evan E. Eichler
Publié 2021

AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

par Jens Luebeck, Ceyda Coruh, Siavash R. Dehkordi, Joshua T. Lange, Kristen M. Turner, Viraj Deshpande, Dave A. Pai, Chao Zhang, Utkrisht Rajkumar, Julie A. Law, Paul S. Mischel, Vineet Bafna
Publié 2020

Programming ultrasensitive threshold response through chemomechanical instability

par Young-Joo Kim, Junho Park, Jae Young Lee, Do-Nyun Kim
Publié 2021

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma

par Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Publié 2021

Measuring dimensionality and purity of high-dimensional entangled states

par Isaac Nape, Valeria Rodríguez-Fajardo, Feng Zhu, Hsiao-Chih Huang, Jonathan Leach, Andrew Forbes
Publié 2021

Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy

par Niels Grote Beverborg, Daniela Später, Ralph Knöll, Alejandro Hidalgo, Steve T. Yeh, Zaher Elbeck, Herman H. W. Silljé, Tim R. Eijgenraam, Humam Siga, Magdalena Zurek, Malin Palmér, Susanne Pehrsson, Tamsin Albery, Nils Bomer, Martijn F. Hoes, Cornelis J. Boogerd, Michael Frisk, Eva van Rooij, Sagar Damle, William E. Louch, Qing-Dong Wang, Regina Fritsche-Danielson, Kenneth R. Chien, Kenny M. Hansson, Adam E. Mullick, Rudolf A. de Boer, Peter van der Meer
Publié 2021

Asymmetric biomimetic transamination of α-keto amides to peptides

par Weiqi Cai, Xuelong Qiao, Hao Zhang, Bo Li, Jianhua Guo, Liangliang Zhang, Wen-Wen Chen, Baoguo Zhao
Publié 2021

Tissue sodium excess is not hypertonic and reflects extracellular volume expansion

par Giacomo Rossitto, Sheon Mary, Jun Yu Chen, Philipp Boder, Khai Syuen Chew, Karla B. Neves, Rheure L. Alves, Augusto C. Montezano, Paul Welsh, Mark C. Petrie, Delyth Graham, Rhian M. Touyz, Christian Delles
Publié 2020

CTCF and transcription influence chromatin structure re-configuration after mitosis

par Haoyue Zhang, Jessica Lam, Di Zhang, Yemin Lan, Marit W. Vermunt, Cheryl A. Keller, Belinda Giardine, Ross C. Hardison, Gerd A. Blobel
Publié 2021