Allosteric modulation of ghrelin receptor signaling by lipids

por Marjorie Damian, Maxime Louet, Antoniel Augusto Severo Gomes, Céline M’Kadmi, Séverine Denoyelle, Sonia Cantel, Sophie Mary, Paulo M. Bisch, Jean-Alain Fehrentz, Laurent J. Catoire, Nicolas Floquet, Jean-Louis Banères
Publicado 2021

High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica

por Ricardo D. Righetto, Leonie Anton, Ricardo Adaixo, Roman P. Jakob, Jasenko Zivanov, Mohamed-Ali Mahi, Philippe Ringler, Torsten Schwede, Timm Maier, Henning Stahlberg
Publicado 2020

A proteomics sample metadata representation for multiomics integration and big data analysis

por Chengxin Dai, Anja Füllgrabe, Julianus Pfeuffer, Elizaveta M. Solovyeva, Jingwen Deng, Pablo Moreno, Selvakumar Kamatchinathan, Deepti Jaiswal Kundu, Nancy George, Silvie Fexova, Björn Grüning, Melanie Christine Föll, Johannes Griss, Marc Vaudel, Enrique Audain, Marie Locard-Paulet, Michael Turewicz, Martin Eisenacher, Julian Uszkoreit, Tim Van Den Bossche, Veit Schwämmle, Henry Webel, Stefan Schulze, David Bouyssié, Savita Jayaram, Vinay Kumar Duggineni, Patroklos Samaras, Mathias Wilhelm, Meena Choi, Mingxun Wang, Oliver Kohlbacher, Alvis Brazma, Irene Papatheodorou, Nuno Bandeira, Eric W. Deutsch, Juan Antonio Vizcaíno, Mingze Bai, Timo Sachsenberg, Lev I. Levitsky, Yasset Perez-Riverol
Publicado 2021

Synthesis runs counter to directional folding of a nascent protein domain

por Xiuqi Chen, Nandakumar Rajasekaran, Kaixian Liu, Christian M. Kaiser
Publicado 2020

A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression

por Hyeonkyeong Kim, Yongsik Cho, Hyeon-Seop Kim, Donghyun Kang, Donghyeon Cheon, Yi-Jun Kim, Moon Jong Chang, Kyoung Min Lee, Chong Bum Chang, Seung-Baik Kang, Hyun Guy Kang, Jin-Hong Kim
Publicado 2020

The receptor PTPRU is a redox sensitive pseudophosphatase

por Iain M. Hay, Gareth W. Fearnley, Pablo Rios, Maja Köhn, Hayley J. Sharpe, Janet E. Deane
Publicado 2020

Addressing MRSA infection and antibacterial resistance with peptoid polymers

por Jiayang Xie, Min Zhou, Yuxin Qian, Zihao Cong, Sheng Chen, Wenjing Zhang, Weinan Jiang, Chengzhi Dai, Ning Shao, Zhemin Ji, Jingcheng Zou, Ximian Xiao, Longqiang Liu, Minzhang Chen, Jin Li, Runhui Liu
Publicado 2021

COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance

por Michele Simonetti, Ning Zhang, Luuk Harbers, Maria Grazia Milia, Silvia Brossa, Thi Thu Huong Nguyen, Francesco Cerutti, Enrico Berrino, Anna Sapino, Magda Bienko, Antonino Sottile, Valeria Ghisetti, Nicola Crosetto
Publicado 2021

Circadian regulation of hedonic appetite in mice by clocks in dopaminergic neurons of the VTA

por C. E. Koch, K. Begemann, J. T. Kiehn, L. Griewahn, J. Mauer, M. E. Hess, A. Moser, S. M. Schmid, J. C. Brüning, H. Oster
Publicado 2020

In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

por M. Martinez-Lage, R. Torres-Ruiz, P. Puig-Serra, P. Moreno-Gaona, M. C. Martin, F. J. Moya, O. Quintana-Bustamante, S. Garcia-Silva, A. M. Carcaboso, P. Petazzi, C. Bueno, J. Mora, H. Peinado, J. C. Segovia, P. Menendez, S. Rodriguez-Perales
Publicado 2020

Magnesium in subaqueous speleothems as a potential palaeotemperature proxy

por Russell Drysdale, Isabelle Couchoud, Giovanni Zanchetta, Ilaria Isola, Eleonora Regattieri, John Hellstrom, Aline Govin, Polychronis C. Tzedakis, Trevor Ireland, Ellen Corrick, Alan Greig, Henri Wong, Leonardo Piccini, Peter Holden, Jon Woodhead
Publicado 2020

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

por Melanie Werner-Klein, Ana Grujovic, Christoph Irlbeck, Milan Obradović, Martin Hoffmann, Huiqin Koerkel-Qu, Xin Lu, Steffi Treitschke, Cäcilia Köstler, Catherine Botteron, Kathrin Weidele, Christian Werno, Bernhard Polzer, Stefan Kirsch, Miodrag Gužvić, Jens Warfsmann, Kamran Honarnejad, Zbigniew Czyz, Giancarlo Feliciello, Isabell Blochberger, Sandra Grunewald, Elisabeth Schneider, Gundula Haunschild, Nina Patwary, Severin Guetter, Sandra Huber, Brigitte Rack, Nadia Harbeck, Stefan Buchholz, Petra Rümmele, Norbert Heine, Stefan Rose-John, Christoph A. Klein
Publicado 2020

Single-component near-infrared optogenetic systems for gene transcription regulation

por Andrii A. Kaberniuk, Mikhail Baloban, Mikhail V. Monakhov, Daria M. Shcherbakova, Vladislav V. Verkhusha
Publicado 2021

Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons

por M. Catarina Silva, Ghata A. Nandi, Sharon Tentarelli, Ian K. Gurrell, Tanguy Jamier, Diane Lucente, Bradford C. Dickerson, Dean G. Brown, Nicholas J. Brandon, Stephen J. Haggarty
Publicado 2020

Inhibition of MRN activity by a telomere protein motif

por Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi
Publicado 2021

Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice

por Eva Hadadi, William Taylor, Xiao-Mei Li, Yetki Aslan, Marthe Villote, Julie Rivière, Gaelle Duvallet, Charlotte Auriau, Sandrine Dulong, Isabelle Raymond-Letron, Sylvain Provot, Annelise Bennaceur-Griscelli, Hervé Acloque
Publicado 2020

The mutREAD method detects mutational signatures from low quantities of cancer DNA

por Juliane Perner, Sujath Abbas, Karol Nowicki-Osuch, Ginny Devonshire, Matthew D. Eldridge, Simon Tavaré, Rebecca C. Fitzgerald
Publicado 2020

A library of ab initio Raman spectra for automated identification of 2D materials

por Alireza Taghizadeh, Ulrik Leffers, Thomas G. Pedersen, Kristian S. Thygesen
Publicado 2020

Uncovering the effects of interface-induced ordering of liquid on crystal growth using machine learning

por Rodrigo Freitas, Evan J. Reed
Publicado 2020

Synaptic plasticity-dependent competition rule influences memory formation

por Yire Jeong, Hye-Yeon Cho, Mujun Kim, Jung-Pyo Oh, Min Soo Kang, Miran Yoo, Han-Sol Lee, Jin-Hee Han
Publicado 2021