Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

por Olli Dufva, Matti Kankainen, Tiina Kelkka, Nodoka Sekiguchi, Shady Adnan Awad, Samuli Eldfors, Bhagwan Yadav, Heikki Kuusanmäki, Disha Malani, Emma I Andersson, Paavo Pietarinen, Leena Saikko, Panu E. Kovanen, Teija Ojala, Dean A. Lee, Thomas P. Loughran, Hideyuki Nakazawa, Junji Suzumiya, Ritsuro Suzuki, Young Hyeh Ko, Won Seog Kim, Shih-Sung Chuang, Tero Aittokallio, Wing C. Chan, Koichi Ohshima, Fumihiro Ishida, Satu Mustjoki
Publicado 2018

Comparative Genome Analysis of Three Eukaryotic Parasites with Differing Abilities To Transform Leukocytes Reveals Key Mediators of <italic toggle="yes">Theileria</italic>-Induced...

por Kyoko Hayashida, Yuichiro Hara, Takashi Abe, Chisato Yamasaki, Atsushi Toyoda, Takehide Kosuge, Yutaka Suzuki, Yoshiharu Sato, Shuichi Kawashima, Toshiaki Katayama, Hiroyuki Wakaguri, Noboru Inoue, Keiichi Homma, Masahito Tada-Umezaki, Yukio Yagi, Yasuyuki Fujii, Takuya Habara, Minoru Kanehisa, Hidemi Watanabe, Kimihito Ito, Takashi Gojobori, Hideaki Sugawara, Tadashi Imanishi, William Weir, Malcolm Gardner, Arnab Pain, Brian Shiels, Masahira Hattori, Vishvanath Nene, Chihiro Sugimoto
Publicado 2012

Femtosecond X-ray emission study of the spin cross-over dynamics in haem proteins

por Dominik Kinschel, Camila Bacellar, Oliviero Cannelli, Boris Sorokin, Tetsuo Katayama, Giulia F. Mancini, Jérémy R. Rouxel, Yuki Obara, Junichi Nishitani, Hironori Ito, Terumasa Ito, Naoya Kurahashi, Chika Higashimura, Shotaro Kudo, Theo Keane, Frederico A. Lima, Wojciech Gawelda, Peter Zalden, Sebastian Schulz, James M. Budarz, Dmitry Khakhulin, Andreas Galler, Christian Bressler, Christopher J. Milne, Thomas Penfold, Makina Yabashi, Toshinori Suzuki, Kazuhiko Misawa, Majed Chergui
Publicado 2020

Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein

por Takuma Hashimoto, Daiki D. Horikawa, Yuki Saito, Hirokazu Kuwahara, Hiroko Kozuka-Hata, Tadasu Shin-I, Yohei Minakuchi, Kazuko Ohishi, Ayuko Motoyama, Tomoyuki Aizu, Atsushi Enomoto, Koyuki Kondo, Sae Tanaka, Yuichiro Hara, Shigeyuki Koshikawa, Hiroshi Sagara, Toru Miura, Shin-ichi Yokobori, Kiyoshi Miyagawa, Yutaka Suzuki, Takeo Kubo, Masaaki Oyama, Yuji Kohara, Asao Fujiyama, Kazuharu Arakawa, Toshiaki Katayama, Atsushi Toyoda, Takekazu Kunieda
Publicado 2016

The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in hepatocellular carcinoma

por Hiroaki Kanzaki, Tetsuhiro Chiba, Junjie Ao, Keisuke Koroki, Kengo Kanayama, Susumu Maruta, Takahiro Maeda, Yuko Kusakabe, Kazufumi Kobayashi, Naoya Kanogawa, Soichiro Kiyono, Masato Nakamura, Takayuki Kondo, Tomoko Saito, Ryo Nakagawa, Sadahisa Ogasawara, Eiichiro Suzuki, Yoshihiko Ooka, Ryosuke Muroyama, Shingo Nakamoto, Shin Yasui, Akinobu Tawada, Makoto Arai, Tatsuo Kanda, Hitoshi Maruyama, Naoya Mimura, Jun Kato, Yoh Zen, Masayuki Ohtsuka, Atsushi Iwama, Naoya Kato
Publicado 2021

Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3.

por Atsushi Miyake, Ikuyo Kou, Yohei Takahashi, Todd A Johnson, Yoji Ogura, Jin Dai, Xusheng Qiu, Atsushi Takahashi, Hua Jiang, Huang Yan, Katsuki Kono, Noriaki Kawakami, Koki Uno, Manabu Ito, Shohei Minami, Haruhisa Yanagida, Hiroshi Taneichi, Naoya Hosono, Taichi Tsuji, Teppei Suzuki, Hideki Sudo, Toshiaki Kotani, Ikuho Yonezawa, Michiaki Kubo, Tatsuhiko Tsunoda, Kota Watanabe, Kazuhiro Chiba, Yoshiaki Toyama, Yong Qiu, Morio Matsumoto, Shiro Ikegawa
Publicado 2013

Extracorporeal membrane oxygenation may decrease the plasma concentration of remdesivir in a patient with severe coronavirus disease 2019

por Satoshi Ide, Sho Saito, Tsubasa Akazawa, Takahito Furuya, Junichi Masuda, Maki Nagashima, Yusuke Asai, Tatsunori Ogawa, Ryohei Yamamoto, Haruhiko Ishioka, Kohei Kanda, Ayako Okuhama, Yuji Wakimoto, Tetsuya Suzuki, Yutaro Akiyama, Yusuke Miyazato, Keiji Nakamura, Takato Nakamoto, Hidetoshi Nomoto, Yuki Moriyama, Masayuki Ota, Shinichiro Morioka, Wataru Matsuda, Tatsuki Uemura, Kentaro Kobayashi, Ryo Sasaki, Daisuke Katagiri, Satoshi Kutsuna, Kayoko Hayakawa, Norio Ohmagari
Publicado 2021

RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions

por Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J.  F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publicado 2020

Author Correction: RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions

por Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J. F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publicado 2021

12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population

por Ryo Takata, Atsushi Takahashi, Masashi Fujita, Yukihide Momozawa, Edward J. Saunders, Hiroki Yamada, Kazuhiro Maejima, Kaoru Nakano, Yuichiro Nishida, Asahi Hishida, Keitaro Matsuo, Kenji Wakai, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Shoichiro Tsugane, Makoto Sasaki, Atsushi Shimizu, Kozo Tanno, Naoko Minegishi, Kichiya Suzuki, Koichi Matsuda, Michiaki Kubo, Johji Inazawa, Shin Egawa, Christopher A. Haiman, Osamu Ogawa, Wataru Obara, Yoichiro Kamatani, Shusuke Akamatsu, Hidewaki Nakagawa
Publicado 2019

MET Amplification and Efficacy of Nivolumab in Patients With NSCLC

por Katsuhiro Yoshimura, MD, PhD, Yusuke Inoue, MD, PhD, Naoki Inui, MD, PhD, Masato Karayama, MD, PhD, Hideki Yasui, MD, PhD, Hironao Hozumi, MD, PhD, Yuzo Suzuki, MD, PhD, Kazuki Furuhashi, MD, PhD, Tomoyuki Fujisawa, MD, PhD, Noriyuki Enomoto, MD, PhD, Yutaro Nakamura, MD, PhD, Haruhiko Sugimura, MD, PhD, Takafumi Suda, MD, PhD
Publicado 2021

Exploring microsatellite instability in patients with advanced hepatocellular carcinoma and its tumor microenvironment

por Shohei Mukai, Hiroaki Kanzaki, Sadahisa Ogasawara, Takamasa Ishino, Keita Ogawa, Miyuki Nakagawa, Kisako Fujiwara, Hidemi Unozawa, Terunao Iwanaga, Takafumi Sakuma, Naoto Fujita, Keisuke Koroki, Kazufumi Kobayashi, Naoya Kanogawa, Soichiro Kiyono, Masato Nakamura, Takayuki Kondo, Tomoko Saito, Ryo Nakagawa, Eiichiro Suzuki, Yoshihiko Ooka, Ryosuke Muroyama, Shingo Nakamoto, Akinobu Tawada, Tetsuhiro Chiba, Makoto Arai, Jun Kato, Manayu Shiina, Masayuki Ota, Jun‐ichiro Ikeda, Yuichi Takiguchi, Masayuki Ohtsuka, Naoya Kato
Publicado 2021

EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma

por Yuko Kusakabe, Tetsuhiro Chiba, Motohiko Oshima, Shuhei Koide, Ola Rizq, Kazumasa Aoyama, Junjie Ao, Tatsuya Kaneko, Hiroaki Kanzaki, Kengo Kanayama, Takahiro Maeda, Tomoko Saito, Ryo Nakagawa, Kazufumi Kobayashi, Soichiro Kiyono, Masato Nakamura, Sadahisa Ogasawara, Eiichiro Suzuki, Shingo Nakamoto, Shin Yasui, Rintaro Mikata, Ryosuke Muroyama, Tatsuo Kanda, Hitoshi Maruyama, Jun Kato, Naoya Mimura, Anqi Ma, Jian Jin, Yoh Zen, Masayuki Otsuka, Atsushi Kaneda, Atsushi Iwama, Naoya Kato
Publicado 2021

Characteristics of aspiration pneumonia patients in acute care hospitals: A multicenter, retrospective survey in Northern Japan.

por Jun Suzuki, Ryoukichi Ikeda, Kengo Kato, Risako Kakuta, Yuta Kobayashi, Akira Ohkoshi, Ryo Ishii, Ai Hirano-Kawamoto, Jun Ohta, Rei Kawata, Tomonori Kanbayashi, Masaki Hatano, Tadahisa Shishido, Yuya Miyakura, Kento Ishigaki, Yasunari Yamauchi, Miho Nakazumi, Takuya Endo, Hiroki Tozuka, Shiori Kitaya, Yuki Numano, Shotaro Koizumi, Yutaro Saito, Mutsuki Unuma, Ken Hashimoto, Eiichi Ishida, Toshiaki Kikuchi, Takayuki Kudo, Kenichi Watanabe, Masaki Ogura, Masaru Tateda, Takatsuna Sasaki, Nobuo Ohta, Tatsuma Okazaki, Yukio Katori
Publicado 2021

Gender-specific analysis for the association between trunk muscle mass and spinal pathologies

por Yusuke Hori, Masatoshi Hoshino, Kazuhide Inage, Masayuki Miyagi, Shinji Takahashi, Shoichiro Ohyama, Akinobu Suzuki, Tadao Tsujio, Hidetomi Terai, Sho Dohzono, Ryuichi Sasaoka, Hiromitsu Toyoda, Minori Kato, Akira Matsumura, Takashi Namikawa, Masahiko Seki, Kentaro Yamada, Hasibullah Habibi, Hamidullah Salimi, Masaomi Yamashita, Tomonori Yamauchi, Takeo Furuya, Sumihisa Orita, Satoshi Maki, Yasuhiro Shiga, Masahiro Inoue, Gen Inoue, Hisako Fujimaki, Kosuke Murata, Ayumu Kawakubo, Daijiro Kabata, Ayumi Shintani, Seiji Ohtori, Masashi Takaso, Hiroaki Nakamura
Publicado 2021

Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging

por Yingji Jin, Yoshito Takeda, Yasushi Kondo, Lokesh P. Tripathi, Sujin Kang, Hikari Takeshita, Hanako Kuhara, Yohei Maeda, Masayoshi Higashiguchi, Kotaro Miyake, Osamu Morimura, Taro Koba, Yoshitomo Hayama, Shohei Koyama, Kaori Nakanishi, Takeo Iwasaki, Satoshi Tetsumoto, Kazuyuki Tsujino, Muneyoshi Kuroyama, Kota Iwahori, Haruhiko Hirata, Takayuki Takimoto, Mayumi Suzuki, Izumi Nagatomo, Ken Sugimoto, Yuta Fujii, Hiroshi Kida, Kenji Mizuguchi, Mari Ito, Takashi Kijima, Hiromi Rakugi, Eisuke Mekada, Isao Tachibana, Atsushi Kumanogoh
Publicado 2018

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

por Erna Davydova, Tadahiro Shimazu, Maren Kirstin Schuhmacher, Magnus E. Jakobsson, Hanneke L. D. M. Willemen, Tongri Liu, Anders Moen, Angela Y. Y. Ho, Jędrzej Małecki, Lisa Schroer, Rita Pinto, Takehiro Suzuki, Ida A. Grønsberg, Yoshihiro Sohtome, Mai Akakabe, Sara Weirich, Masaki Kikuchi, Jesper V. Olsen, Naoshi Dohmae, Takashi Umehara, Mikiko Sodeoka, Valentina Siino, Michael A. McDonough, Niels Eijkelkamp, Christopher J. Schofield, Albert Jeltsch, Yoichi Shinkai, Pål Ø. Falnes
Publicado 2021

An updated version of the global interior ocean biogeochemical data product, GLODAPv2.2021

por S. K. Lauvset, N. Lange, T. Tanhua, H. C. Bittig, A. Olsen, A. Kozyr, M. Álvarez, S. Becker, P. J. Brown, B. R. Carter, B. R. Carter, L. Cotrim da Cunha, R. A. Feely, S. van Heuven, M. Hoppema, M. Ishii, E. Jeansson, S. Jutterström, S. D. Jones, M. K. Karlsen, C. Lo Monaco, P. Michaelis, A. Murata, F. F. Pérez, B. Pfeil, C. Schirnick, R. Steinfeldt, T. Suzuki, B. Tilbrook, A. Velo, R. Wanninkhof, R. J. Woosley, R. M. Key
Publicado 2021

Genome sequence and analysis of the Japanese morning glory Ipomoea nil

por Atsushi Hoshino, Vasanthan Jayakumar, Eiji Nitasaka, Atsushi Toyoda, Hideki Noguchi, Takehiko Itoh, Tadasu Shin-I, Yohei Minakuchi, Yuki Koda, Atsushi J. Nagano, Masaki Yasugi, Mie N. Honjo, Hiroshi Kudoh, Motoaki Seki, Asako Kamiya, Toshiyuki Shiraki, Piero Carninci, Erika Asamizu, Hiroyo Nishide, Sachiko Tanaka, Kyeung-Il Park, Yasumasa Morita, Kohei Yokoyama, Ikuo Uchiyama, Yoshikazu Tanaka, Satoshi Tabata, Kazuo Shinozaki, Yoshihide Hayashizaki, Yuji Kohara, Yutaka Suzuki, Sumio Sugano, Asao Fujiyama, Shigeru Iida, Yasubumi Sakakibara
Publicado 2016

Gene organization in rice revealed by full-length cDNA mapping and gene expression analysis through microarray.

por Kouji Satoh, Koji Doi, Toshifumi Nagata, Naoki Kishimoto, Kohji Suzuki, Yasuhiro Otomo, Jun Kawai, Mari Nakamura, Tomoko Hirozane-Kishikawa, Saeko Kanagawa, Takahiro Arakawa, Juri Takahashi-Iida, Mitsuyoshi Murata, Noriko Ninomiya, Daisuke Sasaki, Shiro Fukuda, Michihira Tagami, Harumi Yamagata, Kanako Kurita, Kozue Kamiya, Mayu Yamamoto, Ari Kikuta, Takahito Bito, Nahoko Fujitsuka, Kazue Ito, Hiroyuki Kanamori, Il-Ryong Choi, Yoshiaki Nagamura, Takashi Matsumoto, Kazuo Murakami, Ken-ichi Matsubara, Piero Carninci, Yoshihide Hayashizaki, Shoshi Kikuchi
Publicado 2007