Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer

por Leisha A Emens, Huilin Ma, Hanwen Wang, Richard J Sové, Aleksander S Popel
Publicado 2021

Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

por Jing Yang, Rong Li, Bin Yuan, Curtis A Clark, Bogang Wu, Justin M Drerup, Tianbao Li, Victor X Jin, Yanfen Hu, Tyler J Curiel
Publicado 2021

TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

por Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
Publicado 2021

Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model

por Lan Wang, Jing Wen, Jie Ren, Emiko Kranz, Shilin Chen, Toshio Kanazawa, Irvin Chen, Yunfeng Lu, Masakazu Kamata
Publicado 2021

Tisagenlecleucel infusion in patients with relapsed/refractory ALL and concurrent serious infection

por Weijie Li, Keith J August, Erin M Hall, Dwight E Yin, Rakesh K Goyal, Atif A Ahmed, Grace S Mitchell, Shawn D St. Peter, Terrie G Flatt, Ibrahim A Ahmed, Richard J Hendrickson, G Doug Myers
Publicado 2021

Impact of C-reactive protein flare-response on oncological outcomes in patients with metastatic renal cell carcinoma treated with nivolumab

por Toshiki Kijima, Shohei Fukuda, Kazutaka Saito, Yosuke Yasuda, Soichiro Yoshida, Minato Yokoyama, Junichiro Ishioka, Yoh Matsuoka, Yukio Kageyama, Yasuhisa Fujii
Publicado 2021

Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer

por Xi Yang, Yan Zhang, Hui Yang, Ping Wan, Ye Hu, YiRen Hu, Mingzhe Ma, Kun Lv
Publicado 2021

In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor...

por In-San Kim, Seohyun Kim, Seong A Kim, Gi-Hoon Nam, Yeonsun Hong, Gi Beom Kim, Yoonjeong Choi, Seokyoung Lee, Yuri Cho, Minsu Kwon, Cherlhyun Jeong, Sehoon Kim
Publicado 2021

Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer

por Tamar Zahavi, Mali Salmon-Divon, Roberto Salgado, Michael Elkin, Esther Hermano, Ariel M. Rubinstein, Prudence A. Francis, Angelo Di Leo, Giuseppe Viale, Evandro de Azambuja, Lieveke Ameye, Christos Sotiriou, Asher Salmon, Nataly Kravchenko-Balasha, Amir Sonnenblick
Publicado 2021

RIPK1 is a negative mediator in Aquaporin 1-driven triple-negative breast carcinoma progression and metastasis

por Zhuming Yin, Wenlin Chen, Jian Yin, Jingyan Sun, Qianrong Xie, Min Wu, Fanxin Zeng, Huiwen Ren
Publicado 2021

High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia

por Ching-Hung Lin, Ruby Yun-Ju Huang, Tzu-Pin Lu, Kuan-Ting Kuo, Ko-Yun Lo, Ching-Hsuan Chen, I-Chun Chen, Yen-Shen Lu, Eric Y. Chuang, Jean Paul Thiery, Chiun-Sheng Huang, Ann-Lii Cheng
Publicado 2021

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

por Steven P. Angus, Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, J. Felix Olivares-Quintero, Michael P. East, Maki Tanioka, Jon S. Zawistowski, Darshan Singh, Noah Sciaky, Xin Chen, Xiaping He, Naim U. Rashid, Lynn Chollet-Hinton, Cheng Fan, Matthew G. Soloway, Patricia A. Spears, Stuart Jefferys, Joel S. Parker, Kristalyn K. Gallagher, Andres Forero-Torres, Ian E. Krop, Alastair M. Thompson, Rashmi Murthy, Michael L. Gatza, Charles M. Perou, H. Shelton Earp, Lisa A. Carey, Gary L. Johnson
Publicado 2021

Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study

por Patrick Leo, Andrew Janowczyk, Robin Elliott, Nafiseh Janaki, Kaustav Bera, Rakesh Shiradkar, Xavier Farré, Pingfu Fu, Ayah El-Fahmawi, Mohammed Shahait, Jessica Kim, David Lee, Kosj Yamoah, Timothy R. Rebbeck, Francesca Khani, Brian D. Robinson, Lauri Eklund, Ivan Jambor, Harri Merisaari, Otto Ettala, Pekka Taimen, Hannu J. Aronen, Peter J. Boström, Ashutosh Tewari, Cristina Magi-Galluzzi, Eric Klein, Andrei Purysko, Natalie NC Shih, Michael Feldman, Sanjay Gupta, Priti Lal, Anant Madabhushi
Publicado 2021

PARP inhibitors promote stromal fibroblast activation by enhancing CCL5 autocrine signaling in ovarian cancer

por Xiaoting Li, Tian Fang, Sen Xu, Ping Jin, Dongchen Zhou, Zhengzheng Wang, Huayi Li, Zongyuan Yang, Gang Chen, Xu Zheng, Yu Xia, Xiao Wei, Zeyu Zhang, Xin Yang, Ya Wang, Qinglei Gao
Publicado 2021

The impact of lymphedema on health-related quality of life up to 10 years after breast cancer treatment

por Mads G. Jørgensen, Navid M. Toyserkani, Frederik G. Hansen, Anette Bygum, Jens A. Sørensen
Publicado 2021

The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib

por Tao Shen, Xueqing Hu, Xuan Liu, Vivek Subbiah, Blaine H. M. Mooers, Jie Wu
Publicado 2021

Automated percent mammographic density, mammographic texture variation, and risk of breast cancer: a nested case-control study

por Erica T. Warner, Megan S. Rice, Oana A. Zeleznik, Erin E. Fowler, Divya Murthy, Celine M. Vachon, Kimberly A. Bertrand, Bernard A. Rosner, John Heine, Rulla M. Tamimi
Publicado 2021

Risk of primary lung cancer after adjuvant radiotherapy in breast cancer—a large population-based study

por Anna-Karin Wennstig, Charlotta Wadsten, Hans Garmo, Mikael Johansson, Irma Fredriksson, Carl Blomqvist, Lars Holmberg, Greger Nilsson, Malin Sund
Publicado 2021

The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer

por Zhenbo Tu, Johannes Schmoellerl, Odette Mariani, Yurong Zheng, Yi Hu, Anne Vincent-Salomon, Antoine E. Karnoub
Publicado 2021

A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival

por Sipeng Shen, Yongyue Wei, Yi Li, Weiwei Duan, Xuesi Dong, Lijuan Lin, Dongfang You, Adonina Tardon, Chu Chen, John K. Field, Rayjean J. Hung, Geoffrey Liu, Dakai Zhu, Christopher I. Amos, Li Su, Yang Zhao, Zhibin Hu, Hongbing Shen, Ruyang Zhang, Feng Chen, David C. Christiani
Publicado 2021