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  1. 3281
    The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites
    “...)-sensitive (K13 wild-type) Plasmodium falciparum strain is exposed to ART derivatives...”
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  2. 3282
    An expandable embryonic stem cell-derived Purkinje neuron progenitor population that exhibits in vivo maturation in the adult mouse cerebellum
    “... cerebellum of either wild-type mice or a strain lacking Purkinje cells (L7cre-ERCC1 knockout), GFP-labeled...”
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  3. 3283
    Restriction and modification of deoxyarchaeosine (dG+)-containing phage 9 g DNA
    “... chromatography-mass spectrometry. A number of wild-type E. coli bacteria restricted phage 9 g, indicating natural...”
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  4. 3284
    Fungus-derived hydroxyl radicals kill hepatic cells by enhancing nuclear transglutaminase
    “... of either human hepatic cells or mouse primary hepatocytes derived from wild-type but not TG2−/− mice...”
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  5. 3285
    Orthosteric- versus allosteric-dependent activation of the GABAA receptor requires numerically distinct subunit level rearrangements
    por Jahanshah Amin, Meena S. Subbarayan
    Publicado 2017
    “... full GABA α1β2γ2 receptor agonists. Here, we coexpressed varying ratios of RNAs encoding the wild-type...”
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  6. 3286
    A sex-specific reconstitution bias in the competitive CD45.1/CD45.2 congenic bone marrow transplant model
    “... of sex on this bias, remain uncertain. We performed bone marrow transplants with wild-type CD45.1 and CD...”
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  7. 3287
    Deletion of the B-B’ and C-C’ regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression
    “... of recombinant AAV (rAAV). The packaging ability was compared between ITRΔBC rAAV and wild-type (wt) ITR rAAV...”
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  8. 3288
    Adaptive mutations of neuraminidase stalk truncation and deglycosylation confer enhanced pathogenicity of influenza A viruses
    “... adaptation of avian influenza A viruses (IAVs) from wild aquatic birds to domestic poultry. We identified...”
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  9. 3289
    In silico investigation of a KCNQ1 mutation associated with short QT syndrome
    “... (IKs). A Markov chain (MC) model recapitulating wild type (WT) and V307L mutant IKs kinetics...”
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  10. 3290
    Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice
    “... of Aβ containing deposits in wild-type mice that recapitulates major retinal pathophysiological...”
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  11. 3291
    TNFR1 inhibition with a Nanobody protects against EAE development in mice
    “... demonstrated that intraperitoneally injected TROS is retained more in organs of hTNFR1 Tg mice compared to wild...”
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  12. 3292
    Composition and function of the C1b/C1f region in the ciliary central apparatus
    “.... Comparative analyses of wild-type and C1b-deficient mutant ciliomes revealed that the levels of subunits...”
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  13. 3293
    KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer
    “... and wild-type for these hotspot mutations, respectively, according to standard PCR-based analyses on tissue...”
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  14. 3294
    Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo
    “...)-treated wild-type Zucker rats (T1DM) and Zucker diabetic fatty (ZDF) rats (T2DM). Intermediary metabolism...”
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  15. 3295
    Analyses of the three 1-Cys Peroxiredoxins from Aspergillus fumigatus reveal that cytosolic Prx1 is central to H2O2 metabolism and virulence
    “... Prx displayed higher sensitivity to oxidative challenge in comparison with the wild-type strain...”
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  16. 3296
    Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells
    “... line (B16F10) was determined by migration and invasion assays with transwell system. ATP-treated wild...”
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  17. 3297
    Identification and pathogenomic analysis of an Escherichia coli strain producing a novel Shiga toxin 2 subtype
    “...h in E. coli strains isolated from wild marmots in the Qinghai-Tibetan plateau, China. Stx2h shares...”
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  18. 3298
    Autosomal dominant transmission of complicated hereditary spastic paraplegia due to a dominant negative mutation of KIF1A, SPG30 gene
    “... with p.T258M mutation has reduced motor activity and exerts a dominant negative effect on wild-type KIF1A...”
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  19. 3299
    Brain-derived neurotrophic factor is regulated via MyD88/NF-κB signaling in experimental Streptococcus pneumoniae meningitis
    “...), regulates BDNF expression in experimental S. pneumoniae meningitis. MyD88 knockout (myd88−/−) mice and wild...”
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  20. 3300
    SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2
    “...Abstract Wild type mitochondrial isocitrate dehydrogenase (IDH2) was previously reported to produce...”
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