Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage

por Pietro Carotenuto, Francesco Amato, Andrea Lampis, Colin Rae, Somaieh Hedayat, Maria C. Previdi, Domenico Zito, Maya Raj, Vincenza Guzzardo, Francesco Sclafani, Andrea Lanese, Claudia Parisi, Caterina Vicentini, Ian Said-Huntingford, Jens C. Hahne, Albert Hallsworth, Vladimir Kirkin, Kate Young, Ruwaida Begum, Andrew Wotherspoon, Kyriakos Kouvelakis, Sergio Xavier Azevedo, Vasiliki Michalarea, Rosie Upstill-Goddard, Sheela Rao, David Watkins, Naureen Starling, Anguraj Sadanandam, David K. Chang, Andrew V. Biankin, Nigel B. Jamieson, Aldo Scarpa, David Cunningham, Ian Chau, Paul Workman, Matteo Fassan, Nicola Valeri, Chiara Braconi
Publicado 2021

A missense variant in SHARPIN mediates Alzheimer’s disease-specific brain damages

por Jun Young Park, Dongsoo Lee, Jang Jae Lee, Jungsoo Gim, Tamil Iniyan Gunasekaran, Kyu Yeong Choi, Sarang Kang, Ah Ra Do, Jinyeon Jo, Juhong Park, Kyungtaek Park, Donghe Li, Sanghun Lee, Hoowon Kim, Immanuel Dhanasingh, Suparna Ghosh, Seula Keum, Jee Hye Choi, Gyun Jee Song, Lee Sael, Sangmyung Rhee, Simon Lovestone, Eunae Kim, Seung Hwan Moon, Byeong C. Kim, SangYun Kim, Andrew J. Saykin, Kwangsik Nho, Sung Haeng Lee, Lindsay A. Farrer, Gyungah R. Jun, Sungho Won, Kun Ho Lee, for the Alzheimer’s Disease Neuroimaging Initiative
Publicado 2021

Inter-laboratory mass spectrometry dataset based on passive sampling of drinking water for non-target analysis

por Bastian Schulze, Denice van Herwerden, Ian Allan, Lubertus Bijlsma, Nestor Etxebarria, Martin Hansen, Sylvain Merel, Branislav Vrana, Reza Aalizadeh, Bernard Bajema, Florian Dubocq, Gianluca Coppola, Aurélie Fildier, Pavla Fialová, Emil Frøkjær, Roman Grabic, Pablo Gago-Ferrero, Thorsten Gravert, Juliane Hollender, Nina Huynh, Griet Jacobs, Tim Jonkers, Sarit Kaserzon, Marja Lamoree, Julien Le Roux, Teresa Mairinger, Christelle Margoum, Giuseppe Mascolo, Emmanuelle Mebold, Frank Menger, Cécile Miège, Jeroen Meijer, Régis Moilleron, Sapia Murgolo, Massimo Peruzzo, Martijn Pijnappels, Malcolm Reid, Claudio Roscioli, Coralie Soulier, Sara Valsecchi, Nikolaos Thomaidis, Emmanuelle Vulliet, Robert Young, Saer Samanipour
Publicado 2021

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape

por Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publicado 2021

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

por Alberto A. Amarilla, Julian D. J. Sng, Rhys Parry, Joshua M. Deerain, James R. Potter, Yin Xiang Setoh, Daniel J. Rawle, Thuy T. Le, Naphak Modhiran, Xiaohui Wang, Nias Y. G. Peng, Francisco J. Torres, Alyssa Pyke, Jessica J. Harrison, Morgan E. Freney, Benjamin Liang, Christopher L. D. McMillan, Stacey T. M. Cheung, Darwin J. Da Costa Guevara, Joshua M. Hardy, Mark Bettington, David A. Muller, Fasséli Coulibaly, Frederick Moore, Roy A. Hall, Paul R. Young, Jason M. Mackenzie, Jody Hobson-Peters, Andreas Suhrbier, Daniel Watterson, Alexander A. Khromykh
Publicado 2021

Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts

por Liang Ma, Zehua Chen, Da Wei Huang, Geetha Kutty, Mayumi Ishihara, Honghui Wang, Amr Abouelleil, Lisa Bishop, Emma Davey, Rebecca Deng, Xilong Deng, Lin Fan, Giovanna Fantoni, Michael Fitzgerald, Emile Gogineni, Jonathan M. Goldberg, Grace Handley, Xiaojun Hu, Charles Huber, Xiaoli Jiao, Kristine Jones, Joshua Z. Levin, Yueqin Liu, Pendexter Macdonald, Alexandre Melnikov, Castle Raley, Monica Sassi, Brad T. Sherman, Xiaohong Song, Sean Sykes, Bao Tran, Laura Walsh, Yun Xia, Jun Yang, Sarah Young, Qiandong Zeng, Xin Zheng, Robert Stephens, Chad Nusbaum, Bruce W. Birren, Parastoo Azadi, Richard A. Lempicki, Christina A. Cuomo, Joseph A. Kovacs
Publicado 2016

Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

por Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda, Leonard D. Goldstein, Mustafa A. Barbhuiya, Markus S. Schröder, Sreelakshmi K. Sreenivasamurthy, Sun-Whe Kim, Sameer Phalke, Kushal Suryamohan, Kayla Lee, Papia Chakraborty, Vasumathi Kode, Xiaoshan Shi, Aditi Chatterjee, Keshava Datta, Aafaque A. Khan, Tejaswini Subbannayya, Jing Wang, Subhra Chaudhuri, Sanjiv Gupta, Braj Raj Shrivastav, Bijay S. Jaiswal, Satish S. Poojary, Shushruta Bhunia, Patricia Garcia, Carolina Bizama, Lorena Rosa, Wooil Kwon, Hongbeom Kim, Youngmin Han, Thakur Deen Yadav, Vedam L. Ramprasad, Amitabha Chaudhuri, Zora Modrusan, Juan Carlos Roa, Pramod Kumar Tiwari, Jin-Young Jang, Somasekar Seshagiri
Publicado 2020

Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity

por Wen Fong Ooi, Manjie Xing, Chang Xu, Xiaosai Yao, Muhammad Khairul Ramlee, Mei Chee Lim, Fan Cao, Kevin Lim, Deepak Babu, Lai-Fong Poon, Joyce Lin Suling, Aditi Qamra, Astrid Irwanto, James Qu Zhengzhong, Tannistha Nandi, Ai Ping Lee-Lim, Yang Sun Chan, Su Ting Tay, Ming Hui Lee, James O. J. Davies, Wai Keong Wong, Khee Chee Soo, Weng Hoong Chan, Hock Soo Ong, Pierce Chow, Chow Yin Wong, Sun Young Rha, Jianjun Liu, Axel M. Hillmer, Jim R. Hughes, Steve Rozen, Bin Tean Teh, Melissa Jane Fullwood, Shang Li, Patrick Tan
Publicado 2016

Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors

por Matthew S. Dietz, Thomas L. Sutton, Brett S. Walker, Charles E. Gast, Luai Zarour, Sidharth K. Sengupta, John R. Swain, Jennifer Eng, Michael Parappilly, Kristen Limbach, Ariana Sattler, Erik Burlingame, Yuki Chin, Austin Gower, Jose L. Montoya Mira, Ajay Sapre, Yu-Jui Chiu, Daniel R. Clayburgh, SuEllen J. Pommier, Jeremy P. Cetnar, Jared M. Fischer, Jerry J. Jaboin, Rodney F. Pommier, Brett C. Sheppard, V. Liana Tsikitis, Alison H. Skalet, Skye C. Mayo, Charles D. Lopez, Joe W. Gray, Gordon B. Mills, Zahi Mitri, Young Hwan Chang, Koei Chin, Melissa H. Wong
Publicado 2021

Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

por Guillaume Tetreau, Anne-Sophie Banneville, Elena A. Andreeva, Aaron S. Brewster, Mark S. Hunter, Raymond G. Sierra, Jean-Marie Teulon, Iris D. Young, Niamh Burke, Tilman A. Grünewald, Joël Beaudouin, Irina Snigireva, Maria Teresa Fernandez-Luna, Alister Burt, Hyun-Woo Park, Luca Signor, Jayesh A. Bafna, Rabia Sadir, Daphna Fenel, Elisabetta Boeri-Erba, Maria Bacia, Ninon Zala, Frédéric Laporte, Laurence Després, Martin Weik, Sébastien Boutet, Martin Rosenthal, Nicolas Coquelle, Manfred Burghammer, Duilio Cascio, Michael R. Sawaya, Mathias Winterhalter, Enrico Gratton, Irina Gutsche, Brian Federici, Jean-Luc Pellequer, Nicholas K. Sauter, Jacques-Philippe Colletier
Publicado 2020

Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling

por Ismael A. Vergara, Christopher P. Mintoff, Shahneen Sandhu, Lachlan McIntosh, Richard J. Young, Stephen Q. Wong, Andrew Colebatch, Daniel L. Cameron, Julia Lai Kwon, Rory Wolfe, Angela Peng, Jason Ellul, Xuelin Dou, Clare Fedele, Samantha Boyle, Gisela Mir Arnau, Jeanette Raleigh, Athena Hatzimihalis, Pacman Szeto, Jennifer Mooi, Daniel S. Widmer, Phil F. Cheng, Valerie Amann, Reinhard Dummer, Nicholas Hayward, James Wilmott, Richard A. Scolyer, Raymond J. Cho, David Bowtell, Heather Thorne, Kathryn Alsop, Stephen Cordner, Noel Woodford, Jodie Leditschke, Patricia O’Brien, Sarah-Jane Dawson, Grant A. McArthur, Graham J. Mann, Mitchell P. Levesque, Anthony T. Papenfuss, Mark Shackleton
Publicado 2021

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

por Mitesh J. Borad, Jan B. Egan, Rachel M. Condjella, Winnie S. Liang, Rafael Fonseca, Nicole R. Ritacca, Ann E. McCullough, Michael T. Barrett, Katherine S. Hunt, Mia D. Champion, Maitray D. Patel, Scott W. Young, Alvin C. Silva, Thai H. Ho, Thorvardur R. Halfdanarson, Robert R. McWilliams, Konstantinos N. Lazaridis, Ramesh K. Ramanathan, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Cuyugan, Jacquelyn McDonald, Jonathan Adkins, Stephen D. Mastrian, Riccardo Valdez, Dawn E. Jaroszewski, Daniel D. Von Hoff, David W. Craig, A. Keith Stewart, John D. Carpten, Alan H. Bryce
Publicado 2016

Ten‐Year Trends in Coronary Bifurcation Percutaneous Coronary Intervention: Prognostic Effects of Patient and Lesion Characteristics, Devices, and Techniques

por Joo Myung Lee, Seung Hun Lee, Juwon Kim, Ki Hong Choi, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo‐Yong Hahn, Jin‐Ho Choi, Seung‐Hyuk Choi, Hyo‐Soo Kim, Woo Jung Chun, Chang‐Wook Nam, Seung‐Ho Hur, Seung Hwan Han, Seung‐Woon Rha, In‐Ho Chae, Jin‐Ok Jeong, Jung Ho Heo, Junghan Yoon, Do‐Sun Lim, Jong‐Seon Park, Myeong‐Ki Hong, Joon‐Hyung Doh, Kwang Soo Cha, Doo‐Il Kim, Sang Yeub Lee, Kiyuk Chang, Byung‐Hee Hwang, So‐Yeon Choi, Myung Ho Jeong, Soon‐Jun Hong, Bon‐Kwon Koo, Hyeon‐Cheol Gwon
Publicado 2021

Early experience of COVID-19 vaccination in adults with systemic rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey

por Jasvinder A Singh, Jinoos Yazdany, Namrata Singh, Zachary S Wallace, Bruce Miller, Maggie Larche, Lisa G Rider, Eimear Duff, Rebecca Grainger, Tamer A Gheita, Jean W Liew, Emily Sirotich, Carly Harrison, Philip C Robinson, Kristen J Young, Jeffrey A Sparks, Gary Foster, Suleman Bhana, Wendy Costello, Jonathan S Hausmann, Paul Sufka, Alfred Hyoungju Kim, Akpabio Akpabio, Michal Nudel, Catherine L Hill, Serena Mingolla, Karen L Durrant, Mitchell Levine, Evelyn Hsieh, Richard A Howard, John Wallace, Inita Bulina, Adam Kilian, Sebastian Eduardo Sattui, Kevin Kennedy, Michael Putman, Tarin T Moni, Aman Dev Singh, Lina El Kibbi, David F L Liew, Chieh Lo, Candace A Palmerlee
Publicado 2021

Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I

por Stephen M. Keable, Adrian Kölsch, Philipp S. Simon, Medhanjali Dasgupta, Ruchira Chatterjee, Senthil Kumar Subramanian, Rana Hussein, Mohamed Ibrahim, In-Sik Kim, Isabel Bogacz, Hiroki Makita, Cindy C. Pham, Franklin D. Fuller, Sheraz Gul, Daniel Paley, Louise Lassalle, Kyle D. Sutherlin, Asmit Bhowmick, Nigel W. Moriarty, Iris D. Young, Johannes P. Blaschke, Casper de Lichtenberg, Petko Chernev, Mun Hon Cheah, Sehan Park, Gisu Park, Jangwoo Kim, Sang Jae Lee, Jaehyun Park, Kensuke Tono, Shigeki Owada, Mark S. Hunter, Alexander Batyuk, Roland Oggenfuss, Mathias Sander, Serhane Zerdane, Dmitry Ozerov, Karol Nass, Henrik Lemke, Roman Mankowsky, Aaron S. Brewster, Johannes Messinger, Nicholas K. Sauter, Vittal K. Yachandra, Junko Yano, Athina Zouni, Jan Kern
Publicado 2021

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

por Kevin J. Selva, Carolien E. van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, Brendon Y. Chua, Samantha K. Davis, Thi H. O. Nguyen, Louise C. Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C. Jackson, Katie L. Flanagan, Jane Crowe, Shidan Tosif, Melanie R. Neeland, Philip Sutton, Paul V. Licciardi, Nigel W. Crawford, Allen C. Cheng, Denise L. Doolan, Fatima Amanat, Florian Krammer, Keith Chappell, Naphak Modhiran, Daniel Watterson, Paul Young, Wen Shi Lee, Bruce D. Wines, P. Mark Hogarth, Robyn Esterbauer, Hannah G. Kelly, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Kelly B. Arnold, Katherine Kedzierska, Amy W. Chung
Publicado 2021

Single cell derived mRNA signals across human kidney tumors

por Matthew D. Young, Thomas J. Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez, Kwasi Kwakwa, Eleonora Khabirova, Gerda Kildisiute, Thomas R. W. Oliver, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Federico Comitani, Alice Piapi, Eva Bugallo-Blanco, Christine Thevanesan, Christina Burke, Elena Prigmore, Kirsty Ambridge, Kenny Roberts, Felipe A. Vieira Braga, Tim H. H. Coorens, Ignacio Del Valle, Anna Wilbrey-Clark, Lira Mamanova, Grant D. Stewart, Vincent J. Gnanapragasam, Dyanne Rampling, Neil Sebire, Nicholas Coleman, Liz Hook, Anne Warren, Muzlifah Haniffa, Marcel Kool, Stefan M. Pfister, John C. Achermann, Xiaoling He, Roger A. Barker, Adam Shlien, Omer A. Bayraktar, Sarah A. Teichmann, Frank C. Holstege, Kerstin B. Meyer, Jarno Drost, Karin Straathof, Sam Behjati
Publicado 2021

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module

por Gerard W. Dougherty, Katsutoshi Mizuno, Tabea Nöthe-Menchen, Yayoi Ikawa, Karsten Boldt, Asaf Ta-Shma, Isabella Aprea, Katsura Minegishi, Yuan-Ping Pang, Petra Pennekamp, Niki T. Loges, Johanna Raidt, Rim Hjeij, Julia Wallmeier, Huda Mussaffi, Zeev Perles, Orly Elpeleg, Franziska Rabert, Hidetaka Shiratori, Stef J. Letteboer, Nicola Horn, Samuel Young, Timo Strünker, Friederike Stumme, Claudius Werner, Heike Olbrich, Katsuyoshi Takaoka, Takahiro Ide, Wang Kyaw Twan, Luisa Biebach, Jörg Große-Onnebrink, Judith A. Klinkenbusch, Kavita Praveen, Diana C. Bracht, Inga M. Höben, Katrin Junger, Jana Gützlaff, Sandra Cindrić, Micha Aviram, Thomas Kaiser, Yasin Memari, Petras P. Dzeja, Bernd Dworniczak, Marius Ueffing, Ronald Roepman, Kerstin Bartscherer, Nicholas Katsanis, Erica E. Davis, Israel Amirav, Hiroshi Hamada, Heymut Omran
Publicado 2020

The Household Water Insecurity Experiences (HWISE) Scale: comparison scores from 27 sites in 22 countries

por Justin Stoler, Joshua D. Miller, Ellis A. Adams, Farooq Ahmed, Mallika Alexander, Gershim Asiki, Mobolanle Balogun, Michael J. Boivin, Alexandra Brewis, Genny Carrillo, Kelly Chapman, Stroma Cole, Shalean M. Collins, Jorge Escobar-Vargas, Hassan Eini-Zinab, Matthew C. Freeman, Monet Ghorbani, Ashley Hagaman, Nicola Hawley, Zeina Jamaluddine, Wendy E. Jepson, Divya Krishnakumar, Kenneth Maes, Jyoti Mathad, Jonathan Maupin, Patrick Mbullo Owuor, Milton Marin Morales, Javier Morán-Martínez, Nasrin Omidvar, Amber L. Pearson, Sabrina Rasheed, Asher Y. Rosinger, Luisa Samayoa-Figueroa, Ernesto C. Sánchez-Rodríguez, Marianne V. Santoso, Roseanne C. Schuster, Mahdieh Sheikhi, Sonali Srivastava, Chad Staddon, Andrea Sullivan, Yihenew Tesfaye, Alex Trowell, Desire Tshala-Katumbay, Raymond Tutu, Cassandra L. Workman, Amber Wutich, Sera L. Young
Publicado 2021

Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.

por Matthew R Henn, Christian L Boutwell, Patrick Charlebois, Niall J Lennon, Karen A Power, Alexander R Macalalad, Aaron M Berlin, Christine M Malboeuf, Elizabeth M Ryan, Sante Gnerre, Michael C Zody, Rachel L Erlich, Lisa M Green, Andrew Berical, Yaoyu Wang, Monica Casali, Hendrik Streeck, Allyson K Bloom, Tim Dudek, Damien Tully, Ruchi Newman, Karen L Axten, Adrianne D Gladden, Laura Battis, Michael Kemper, Qiandong Zeng, Terrance P Shea, Sharvari Gujja, Carmen Zedlack, Olivier Gasser, Christian Brander, Christoph Hess, Huldrych F Günthard, Zabrina L Brumme, Chanson J Brumme, Suzane Bazner, Jenna Rychert, Jake P Tinsley, Ken H Mayer, Eric Rosenberg, Florencia Pereyra, Joshua Z Levin, Sarah K Young, Heiko Jessen, Marcus Altfeld, Bruce W Birren, Bruce D Walker, Todd M Allen
Publicado 2012