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  1. 5001
    Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
    “... based on animal and human cohort studies, and discusses the ethical, legal, and social implications...”
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  2. 5002
    Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons
    “...Disruption of autophagy function in cellular and animal models of tauopathy increases tau...”
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  3. 5003
    Chytrid fungus infection in zebrafish demonstrates that the pathogen can parasitize non-amphibian vertebrate hosts
    “...New infections of the amphibian chytrid fungus could arise from other animal reservoirs...”
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  4. 5004
    Deconvoluting hepatic processing of carbon nanotubes
    “... their distribution and toxicity in vivo. Here, the authors use animal models to show that, while the bulk...”
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  5. 5005
    Small nucleoli are a cellular hallmark of longevity
    “...Animal lifespan is plastic and is regulated by conserved signalling pathways. Here, Tikuet al.show...”
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  6. 5006
    A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium
    “... force at the bacterial cytoplasmic membrane, and extends animal survival during systemic infection....”
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  7. 5007
    Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
    “... in these animals....”
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  8. 5008
    Impact of artificial light at night on diurnal plant-pollinator interactions
    por Simone Giavi, Colin Fontaine, Eva Knop
    Publicado 2021
    “... and animals, including disruption of nocturnal pollination. Here, Giavi et al. show that artificial light...”
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  9. 5009
    Divergent trends in functional and phylogenetic structure in reptile communities across Africa
    “...The biogeographic drivers of reptile diversity are poorly understood relative to other animal...”
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  10. 5010
    Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter
    “... identified animal and fungal genes in this system originated from an ancestral duplication....”
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  11. 5011
    Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis
    “... formed during infection in vivo. Here, Chakraborty et al. demonstrate the formation of biofilms in animal...”
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  12. 5012
    Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model
    “...Animal models that fully recapitulate human CCM pathogenesis are not currently available. Here...”
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  13. 5013
    Long-term consistency in chimpanzee consolation behaviour reflects empathetic personalities
    “...Non-human animals are known to exhibit behaviours suggestive of empathy, but the development...”
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  14. 5014
    Winter temperatures limit population growth rate of a migratory songbird
    “...Population dynamics of migratory animals can be driven by direct, indirect, and potentially...”
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  15. 5015
    Mice in social conflict show rule-observance behavior enhancing long-term benefit
    “...Resolving conflict in an orderly way is beneficial, but it is unclear whether non-human animals...”
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  16. 5016
    Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice
    por Joshua J. White, Roy V. Sillitoe
    Publicado 2017
    “... in dystonia-like signs in the animals which can be alleviated using DBS stimulation of the pathway....”
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  17. 5017
    The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn
    “... of all animals. Here the authors report that TorsinA forms tubular helical filaments with an unusual...”
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  18. 5018
    Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia
    “... function without compromising its cytoprotective function, and shows efficacy in animal models....”
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  19. 5019
    Behavioral and neuronal underpinnings of safety in numbers in fruit flies
    por Clara H. Ferreira, Marta A. Moita
    Publicado 2020
    “...Living in groups allows animals to decrease defenses, enabling other behaviors, but the mechanisms...”
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  20. 5020
    Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
    “... and animals, and identify inhibition of cathepsin D as a driver of ocular toxicity....”
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