Genetic variation, environment and demography intersect to shape Arabidopsis defense metabolite variation across Europe

par Ella Katz, Jia-Jie Li, Benjamin Jaegle, Haim Ashkenazy, Shawn R Abrahams, Clement Bagaza, Samuel Holden, Chris J Pires, Ruthie Angelovici, Daniel J Kliebenstein
Publié 2021

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

par Jenny K Gustafsson, Jazmyne E Davis, Tracy Rappai, Keely G McDonald, Devesha H Kulkarni, Kathryn A Knoop, Simon P Hogan, James AJ Fitzpatrick, Wayne I Lencer, Rodney D Newberry
Publié 2021

Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator

par Michael Jahn, Nick Crang, Markus Janasch, Andreas Hober, Björn Forsström, Kyle Kimler, Alexander Mattausch, Qi Chen, Johannes Asplund-Samuelsson, Elton Paul Hudson
Publié 2021

Single-cell growth inference of Corynebacterium glutamicum reveals asymptotically linear growth

par Joris JB Messelink, Fabian Meyer, Marc Bramkamp, Chase P Broedersz
Publié 2021

Physical observables to determine the nature of membrane-less cellular sub-compartments

par Mathias L Heltberg, Judith Miné-Hattab, Angela Taddei, Aleksandra M Walczak, Thierry Mora
Publié 2021

Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses

par John Lee, Kosuke Kawai, Jeffrey R Holt, Gwenaëlle SG Géléoc
Publié 2021

Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells

par Sarah G Swygert, Dejun Lin, Stephanie Portillo-Ledesma, Po-Yen Lin, Dakota R Hunt, Cheng-Fu Kao, Tamar Schlick, William S Noble, Toshio Tsukiyama
Publié 2021

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins

par Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, Maria Sladowska, Michal Turek, Barbara Uszczynska-Ratajczak, Rishika Kundra, Tomasz Goral, Michele Perni, Christopher M Dobson, Michele Vendruscolo, Agnieszka Chacinska
Publié 2021

Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells

par Suhong Sun, Shuting Li, Zhengnan Luo, Minhui Ren, Shunji He, Guangqin Wang, Zhiyong Liu
Publié 2021

STING mediates immune responses in the closest living relatives of animals

par Arielle Woznica, Ashwani Kumar, Carolyn R Sturge, Chao Xing, Nicole King, Julie K Pfeiffer
Publié 2021

Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation

par Teresa Romeo Luperchio, Leandros Boukas, Li Zhang, Genay Pilarowski, Jenny Jiang, Allison Kalinousky, Kasper D Hansen, Hans T Bjornsson
Publié 2021

Ciliary Hedgehog signaling regulates cell survival to build the facial midline

par Shaun R Abrams, Jeremy F Reiter
Publié 2021

Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures

par Konstantinos Gkatzis, Paolo Panza, Sofia Peruzzo, Didier YR Stainier
Publié 2021

Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

par Yoanna Ariosa-Morejon, Alberto Santos, Roman Fischer, Simon Davis, Philip Charles, Rajesh Thakker, Angus KT Wann, Tonia L Vincent
Publié 2021

6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

par Saeed Daneshmandi, Teresa Cassel, Richard M Higashi, Teresa W-M Fan, Pankaj Seth
Publié 2021

Learning differentially shapes prefrontal and hippocampal activity during classical conditioning

par Jan L Klee, Bryan C Souza, Francesco P Battaglia
Publié 2021

Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

par Lloyd Davis, Inja Radman, Angeliki Goutou, Ailish Tynan, Kieran Baxter, Zhiyan Xi, Jack M O'Shea, Jason W Chin, Sebastian Greiss
Publié 2021

Enhanced Cas12a multi-gene regulation using a CRISPR array separator

par Jens P Magnusson, Antonio Ray Rios, Lingling Wu, Lei S Qi
Publié 2021

Local adaptation and archaic introgression shape global diversity at human structural variant loci

par Stephanie M Yan, Rachel M Sherman, Dylan J Taylor, Divya R Nair, Andrew N Bortvin, Michael C Schatz, Rajiv C McCoy
Publié 2021

Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities

par Swapnesh Panigrahi, Dorothée Murat, Antoine Le Gall, Eugénie Martineau, Kelly Goldlust, Jean-Bernard Fiche, Sara Rombouts, Marcelo Nöllmann, Leon Espinosa, Tâm Mignot
Publié 2021