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  1. 4241
    Holes in the Hologenome: Why Host-Microbe Symbioses Are Not Holobionts
    por Angela E. Douglas, John H. Werren
    Publicado 2016
    “... led to an explosion of research exploring the diversity, ecology, and evolution of microbe-host...”
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  2. 4242
    Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague
    “... to be transmitted via respiratory droplets and its history of weaponization has led to its classification as a...”
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  3. 4243
    Reactive oxygen species scavenging by catalase is important for female Lutzomyia longipalpis fecundity and mortality.
    “.... Depletion of catalase led to a significant increase of mortality and a reduction in the number of developing...”
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  4. 4244
    TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function.
    “.... In contrast, thymic ablation of TR2 in combination with lymphopenia led to lethal multi-organ inflammation...”
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  5. 4245
    Antarctic marine biodiversity and deep-sea hydrothermal vents.
    por Steven L Chown
    Publicado 2012
    “... that investigations of these systems hold for understanding the conditions that may have led to the first appearance...”
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  6. 4246
    Phage encoded H-NS: a potential achilles heel in the bacterial defence system.
    “... an EBPR reactor dominated by Candidatus Accumulibacter phosphatis (CAP), led to the recovery of three...”
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  7. 4247
    Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
    “..., and pretreatment of AIEC bacteria with meprins impaired their ability to bind mannosylated host receptors and led...”
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  8. 4248
    Altered levels of histone deacetylase OsHDT1 affect differential gene expression patterns in hybrid rice.
    “... not affect plant growth in the parent but led to early flowering in the hybrid. Nonadditive up-regulation...”
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  9. 4249
    Influenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting.
    “..., which led to a decrease in the export of other nuclear Crm1 substrates from the nucleus. Interestingly...”
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  10. 4250
    Combinatorial modeling of chromatin features quantitatively predicts DNA replication timing in Drosophila.
    por Federico Comoglio, Renato Paro
    Publicado 2014
    “... feature importance and model analyses led us to derive a simplified, biologically interpretable model...”
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  11. 4251
    Impact of different oseltamivir regimens on treating influenza A virus infection and resistance emergence: insights from a modelling study.
    “... and prophylaxis regimens led to lower efficacies and increased risk of resistance emergence. We conclude...”
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  12. 4252
    How the dynamics and structure of sexual contact networks shape pathogen phylogenies.
    “.... This challenge has led to an interest in methods to infer information about host contact networks from pathogen...”
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  13. 4253
    Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse.
    “... of proinflammation, which led to delayed onset of neurological disease and extension of the life span of 4L;C* mice...”
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  14. 4254
    Deciphering the multifactorial nature of Acinetobacter baumannii pathogenicity.
    “... was avirulent. A combined approach of genomic and phenotypic analyses led to the identification of several...”
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  15. 4255
    Evolutionarily ancient association of the FoxJ1 transcription factor with the motile ciliogenic program.
    “...) that utilizes motile cilia for locomotion, led to a profound disruption in the differentiation of motile cilia...”
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  16. 4256
    Co-evolution of mitochondrial tRNA import and codon usage determines translational efficiency in the green alga Chlamydomonas.
    “... between the mitochondrial codon usage and the nature and amount of imported tRNAs. This led...”
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  17. 4257
    Computer-assisted instruction versus inquiry-based learning: The importance of working memory capacity
    “...The Covid-19 pandemic has led millions of students worldwide to intensify their use of digital...”
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  18. 4258
    Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii.
    “... macrophages in pyroptosis-resistant cells led to sensitization of these resistant macrophages. Our findings...”
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  19. 4259
    Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae.
    “...Reverse genetics in the mosquito Anopheles gambiae by RNAi mediated gene silencing has led...”
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  20. 4260
    A non-coding RNA promotes bacterial persistence and decreases virulence by regulating a regulator in Staphylococcus aureus.
    “... of capsule formation in several strain backgrounds. These phenotypes led to a decreased protection...”
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