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  1. 4321
    Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model
    “... to 20% in mice challenged with a high virus dose at 105 TCID50/mouse. Most notably, GC-376 treatment led...”
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  2. 4322
    A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B
    “... relationship study led to the development of a more stable and potent compound LV-320. We demonstrated that LV...”
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  3. 4323
    A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a
    “... maps with sequence-based transcription factor binding prediction led to the identification of Hnf4a...”
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  4. 4324
    Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction
    “... and overexpression of Cbl, an E3 ubiquitin ligase, led to the conclusion that Cbl specifically promotes JAK2...”
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  5. 4325
    Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine
    “... with an apparent pKa of ~7.5, which corresponds to the general base in catalysis, Glu-34. Moreover, these data led...”
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  6. 4326
    Regulation of retinal pigment epithelial cell phenotype by Annexin A8
    “... differentiation. Ectopic expression of AnxA8 in AnxA8-depleted cells led to decreased neuronal marker staining...”
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  7. 4327
    BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination
    “.... In particular, the NLRP3 alkylation by BOT-4-one led to an impaired ATPase activity of NLRP3, thereby...”
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  8. 4328
    Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells
    “... of human patients with Clostridium difficile or ulcerative colitis. Both DSS and CC led to increased...”
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  9. 4329
    Induction of intracellular ferritin expression in embryo-derived Ixodes scapularis cell line (ISE6)
    “... interference of FER1, through the transfection of dsRNA, led to an increase in mortality and decrease...”
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  10. 4330
    A novel machine learning approach reveals latent vascular phenotypes predictive of renal cancer outcome
    “... of VAMs led to the discovery of 9 vascular features (9VF) that predicted disease-free-survival in a...”
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  11. 4331
    Composition and function of the C1b/C1f region in the ciliary central apparatus
    “... encoding either Spef2A or Cfap69 led to a loss of the entire C1b projection and resulted in an abnormal...”
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  12. 4332
    Investigation of carrier confinement in direct bandgap GeSn/SiGeSn 2D and 0D heterostructures
    “... have significantly intensified. This led to epitaxial studies of GeSn/SiGeSn hetero- and nanostructures...”
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  13. 4333
    Improving catalytic activity of the Baeyer–Villiger monooxygenase-based Escherichia coli biocatalysts for the overproduction of (Z)-11-(heptanoyloxy)undec-9-enoic acid from ricinoleic acid
    “... of carbon and energy source during biotransformations. Glucose feeding into the reaction medium led to a...”
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  14. 4334
    Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability
    “... on cortical motor excitability. However, HD-tDCS over the premotor cortex led to a higher number of responders...”
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  15. 4335
    Rice bran extract supplement improves sleep efficiency and sleep onset in adults with sleep disturbance: A randomized, double-blind, placebo-controlled, polysomnographic study
    “... with the placebo, RBS led to significant polysomnographic changes, including decreased sleep latency (adjusted, P...”
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  16. 4336
    A Benzothiazole Derivative (5g) Induces DNA Damage And Potent G2/M Arrest In Cancer Cells
    “... treatment led to decreased levels of mitochondrial membrane potential and activation of apoptosis...”
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  17. 4337
    Development of a 3D angiogenesis model to study tumour – endothelial cell interactions and the effects of anti-angiogenic drugs
    “.... Inhibition of these proangiogenic factors by using antiangiogenic drugs (bevacizumab and nindetanib) led to a...”
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  18. 4338
    Clinical consequences of BRCA2 hypomorphism
    “..., the co-occurrence in trans with a clearly pathogenic variant led to assume that the other allele...”
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  19. 4339
    Hypertonic stress modulates eNOS function through O-GlcNAc modification at Thr-866
    “...; by contrast, low pH led to a decrease in eNOS O-GlcNAc levels. Notably, eNOS O-GlcNAc protein levels were...”
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  20. 4340
    Arousal influences olfactory abilities in adults with different degree of food neophobia
    “... with food may be led by higher levels of arousal toward foods, rather than different chemosensory functions....”
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