Genomic and experimental data provide new insights into luciferin biosynthesis and bioluminescence evolution in fireflies

por Ru Zhang, Jinwu He, Zhiwei Dong, Guichun Liu, Yuan Yin, Xinying Zhang, Qi Li, Yandong Ren, Yongzhi Yang, Wei Liu, Xianqing Chen, Wenhao Xia, Kang Duan, Fei Hao, Zeshan Lin, Jie Yang, Zhou Chang, Ruoping Zhao, Wenting Wan, Sihan Lu, Yanqiong Peng, Siqin Ge, Wen Wang, Xueyan Li
Publicado 2020

Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity

por Chenxu Yan, Tianshu Zeng, Kailun Lee, Max Nobis, Kim Loh, Luoning Gou, Zefeng Xia, Zhongmin Gao, Mohammed Bensellam, Will Hughes, Jackie Lau, Lei Zhang, Chi Kin Ip, Ronaldo Enriquez, Hanyu Gao, Qiao-Ping Wang, Qi Wu, Jody J. Haigh, D. Ross Laybutt, Paul Timpson, Herbert Herzog, Yan-Chuan Shi
Publicado 2021

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

por Yonghe Wu, Michael Fletcher, Zuguang Gu, Qi Wang, Barbara Costa, Anna Bertoni, Ka-Hou Man, Magdalena Schlotter, Jörg Felsberg, Jasmin Mangei, Martje Barbus, Ann-Christin Gaupel, Wei Wang, Tobias Weiss, Roland Eils, Michael Weller, Haikun Liu, Guido Reifenberger, Andrey Korshunov, Peter Angel, Peter Lichter, Carl Herrmann, Bernhard Radlwimmer
Publicado 2020

Author Correction: An intercross population study reveals genes associated with body size and plumage color in ducks

por Zhengkui Zhou, Ming Li, Hong Cheng, Wenlei Fan, Zhengrong Yuan, Qiang Gao, Yaxi Xu, Zhanbao Guo, Yunsheng Zhang, Jian Hu, Hehe Liu, Dapeng Liu, Weihuang Chen, Zhuqing Zheng, Yong Jiang, Zhiguo Wen, Yongming Liu, Hua Chen, Ming Xie, Qi Zhang, Wei Huang, Wen Wang, Shuisheng Hou, Yu Jiang
Publicado 2018

Technical and imaging factors influencing performance of deep learning systems for diabetic retinopathy

por Michelle Y. T. Yip, Gilbert Lim, Zhan Wei Lim, Quang D. Nguyen, Crystal C. Y. Chong, Marco Yu, Valentina Bellemo, Yuchen Xie, Xin Qi Lee, Haslina Hamzah, Jinyi Ho, Tien-En Tan, Charumathi Sabanayagam, Andrzej Grzybowski, Gavin S. W. Tan, Wynne Hsu, Mong Li Lee, Tien Yin Wong, Daniel S. W. Ting
Publicado 2020

Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design

por Alla Amcheslavsky, Aaron L. Wallace, Monir Ejemel, Qi Li, Conor T. McMahon, Matteo Stoppato, Serena Giuntini, Zachary A. Schiller, Jessica R. Pondish, Jacqueline R. Toomey, Ryan M. Schneider, Jordan Meisinger, Raimond Heukers, Andrew C. Kruse, Eileen M. Barry, Brian G. Pierce, Mark S. Klempner, Lisa A. Cavacini, Yang Wang
Publicado 2021

Federated deep learning for detecting COVID-19 lung abnormalities in CT: a privacy-preserving multinational validation study

por Qi Dou, Tiffany Y. So, Meirui Jiang, Quande Liu, Varut Vardhanabhuti, Georgios Kaissis, Zeju Li, Weixin Si, Heather H. C. Lee, Kevin Yu, Zuxin Feng, Li Dong, Egon Burian, Friederike Jungmann, Rickmer Braren, Marcus Makowski, Bernhard Kainz, Daniel Rueckert, Ben Glocker, Simon C. H. Yu, Pheng Ann Heng
Publicado 2021

Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells

por Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publicado 2021

Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses

por Min Zhao, Kefang Liu, Jiejian Luo, Shuguang Tan, Chuansong Quan, Shuijun Zhang, Yan Chai, Jianxun Qi, Yan Li, Yuhai Bi, Haixia Xiao, Gary Wong, Jianfang Zhou, Taijiao Jiang, Wenjun Liu, Hongjie Yu, Jinghua Yan, Yingxia Liu, Yuelong Shu, Guizhen Wu, Aiping Wu, George F. Gao, William J. Liu
Publicado 2018

An intercross population study reveals genes associated with body size and plumage color in ducks

por Zhengkui Zhou, Ming Li, Hong Cheng, Wenlei Fan, Zhengrong Yuan, Qiang Gao, Yaxi Xu, Zhanbao Guo, Yunsheng Zhang, Jian Hu, Hehe Liu, Dapeng Liu, Weihuang Chen, Zhuqing Zheng, Yong Jiang, Zhiguo Wen, Yongming Liu, Hua Chen, Ming Xie, Qi Zhang, Wei Huang, Wen Wang, Shuisheng Hou, Yu Jiang
Publicado 2018

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

por Dongwen Lv, Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang, Wanyi Hu, Jing Pei, Qi Zhang, Shuo Zhou, Sajid Khan, Xuan Zhang, Nan Hua, Qingping Yang, Sebastian Arango, Weizhou Zhang, Digant Nayak, Shaun K. Olsen, Susan T. Weintraub, Robert Hromas, Marina Konopleva, Yaxia Yuan, Guangrong Zheng, Daohong Zhou
Publicado 2021

An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

por Jia-Bin Wang, Ping Li, Xiao-Long Liu, Qiao-Ling Zheng, Yu-Bin Ma, Ya-Jun Zhao, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Li-Chao Liu, Ning-Zi Lian, Ying-Hong Yang, Chang-Ming Huang, Chao-Hui Zheng
Publicado 2020

Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease

por Luca Bosa, Vritika Batura, Davide Colavito, Karoline Fiedler, Paola Gaio, Conghui Guo, Qi Li, Antonio Marzollo, Claudia Mescoli, Ryusuke Nambu, Jie Pan, Giorgio Perilongo, Neil Warner, Shiqi Zhang, Daniel Kotlarz, Christoph Klein, Scott B. Snapper, Thomas D. Walters, Alberta Leon, Anne M. Griffiths, Mara Cananzi, Aleixo M. Muise
Publicado 2021

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

por Jennifer Y. Ge, Shaokun Shu, Mijung Kwon, Bojana Jovanović, Katherine Murphy, Anushree Gulvady, Anne Fassl, Anne Trinh, Yanan Kuang, Grace A. Heavey, Adrienne Luoma, Cloud Paweletz, Aaron R. Thorner, Kai W. Wucherpfennig, Jun Qi, Myles Brown, Piotr Sicinski, Thomas O. McDonald, David Pellman, Franziska Michor, Kornelia Polyak
Publicado 2020

Direct copolymerization of ethylene with protic comonomers enabled by multinuclear Ni catalysts

por Gang Ji, Zhou Chen, Xiao-Yan Wang, Xiao-Shan Ning, Chong-Jie Xu, Xing-Min Zhang, Wen-Jie Tao, Jun-Fang Li, Yanshan Gao, Qi Shen, Xiu-Li Sun, Hao-Yang Wang, Jun-Bo Zhao, Bo Zhang, Yin-Long Guo, Yanan Zhao, Jiajie Sun, Yi Luo, Yong Tang
Publicado 2021

Dissecting a heterotic gene through GradedPool-Seq mapping informs a rice-improvement strategy

por Changsheng Wang, Shican Tang, Qilin Zhan, Qingqing Hou, Yan Zhao, Qiang Zhao, Qi Feng, Congcong Zhou, Danfeng Lyu, Lingling Cui, Yan Li, Jiashun Miao, Chuanrang Zhu, Yiqi Lu, Yongchun Wang, Ziqun Wang, Jingjie Zhu, Yingying Shangguan, Junyi Gong, Shihua Yang, Wuqi Wang, Jianfu Zhang, Huaan Xie, Xuehui Huang, Bin Han
Publicado 2019

Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice

por Shuangfei Ni, Zemin Ling, Xiao Wang, Yong Cao, Tianding Wu, Ruoxian Deng, Janet L. Crane, Richard Skolasky, Shadpour Demehri, Gehua Zhen, Amit Jain, Panfeng Wu, Dayu Pan, Bo Hu, Xiao Lyu, Yusheng Li, Hao Chen, Huabin Qi, Yun Guan, Xinzhong Dong, Mei Wan, Xuenong Zou, Hongbin Lu, Jianzhong Hu, Xu Cao
Publicado 2019

Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment

por Yujun Cui, Boris V. Schmid, Hanli Cao, Xiang Dai, Zongmin Du, W. Ryan Easterday, Haihong Fang, Chenyi Guo, Shanqian Huang, Wanbing Liu, Zhizhen Qi, Yajun Song, Huaiyu Tian, Min Wang, Yarong Wu, Bing Xu, Chao Yang, Jing Yang, Xianwei Yang, Qingwen Zhang, Kjetill S. Jakobsen, Yujiang Zhang, Nils Chr. Stenseth, Ruifu Yang
Publicado 2020

A coma-free super-high resolution optical spectrometer using 44 high dispersion sub-gratings

por Hua-Tian Tu, An-Qing Jiang, Jian-Ke Chen, Wei-Jie Lu, Kai-Yan Zang, Hao-Qi Tang, Osamu Yoshie, Xiao-Dong Xiang, Young-Pak Lee, Hai-Bin Zhao, Yu-Xiang Zheng, Song-You Wang, Junpeng Guo, Rong-Jun Zhang, Jing Li, Yue-Mei Yang, W. D. Lynch, Liang-Yao Chen
Publicado 2021