A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial

por Pedro M. Folegatti, Kate Harrison, Lorena Preciado-Llanes, Fernando Ramos Lopez, Mustapha Bittaye, Young Chan Kim, Amy Flaxman, Duncan Bellamy, Rebecca Makinson, Jonathan Sheridan, Sasha R. Azar, Rafael Kroon Campos, Mark Tilley, Nguyen Tran, Daniel Jenkin, Ian Poulton, Alison Lawrie, Rachel Roberts, Eleanor Berrie, Shannan L. Rossi, Adrian Hill, Katie J. Ewer, Arturo Reyes-Sandoval
Publicado 2021

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

por Jonathan B. Parr, Eddy Kieto, Fernandine Phanzu, Paul Mansiangi, Kashamuka Mwandagalirwa, Nono Mvuama, Ange Landela, Joseph Atibu, Solange Umesumbu Efundu, Jean W. Olenga, Kyaw Lay Thwai, Camille E. Morgan, Madeline Denton, Alison Poffley, Jonathan J. Juliano, Pomie Mungala, Joris L. Likwela, Eric M. Sompwe, Eric Rogier, Antoinette K. Tshefu, Adrien N’Siala, Albert Kalonji
Publicado 2021

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

por Bo Wang, Evangelia E. Tsakiridis, Shuman Zhang, Andrea Llanos, Eric M. Desjardins, Julian M. Yabut, Alexander E. Green, Emily A. Day, Brennan K. Smith, James S. V. Lally, Jianhan Wu, Amogelang R. Raphenya, Krishna A. Srinivasan, Andrew G. McArthur, Shingo Kajimura, Jagdish Suresh Patel, Michael G. Wade, Katherine M. Morrison, Alison C. Holloway, Gregory R. Steinberg
Publicado 2021

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

por Qian Zhang, Julia Sidorenko, Baptiste Couvy-Duchesne, Riccardo E. Marioni, Margaret J. Wright, Alison M. Goate, Edoardo Marcora, Kuan-lin Huang, Tenielle Porter, Simon M. Laws, Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Perminder S. Sachdev, Karen A. Mather, Nicola J. Armstrong, Anbupalam Thalamuthu, Henry Brodaty, Loic Yengo, Jian Yang, Naomi R. Wray, Allan F. McRae, Peter M. Visscher
Publicado 2020

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

por Paulina Bartuzi, Daniel D. Billadeau, Robert Favier, Shunxing Rong, Daphne Dekker, Alina Fedoseienko, Hille Fieten, Melinde Wijers, Johannes H. Levels, Nicolette Huijkman, Niels Kloosterhuis, Henk van der Molen, Gemma Brufau, Albert K. Groen, Alison M. Elliott, Jan Albert Kuivenhoven, Barbara Plecko, Gernot Grangl, Julie McGaughran, Jay D. Horton, Ezra Burstein, Marten H. Hofker, Bart van de Sluis
Publicado 2016

Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries

por Hung-Ju Hsu, Chao-Ping Tung, Chung-Ming Yu, Chi-Yung Chen, Hong-Sen Chen, Yu-Chuan Huang, Pei-Hsun Tsai, Su-I Lin, Hung-Pin Peng, Yi-Kai Chiu, Yueh-Liang Tsou, Wei-Ying Kuo, Jhih-Wei Jian, Fei-Hung Hung, Chiao-Yun Hsieh, Michael Hsiao, Simon Shih-Hsien Chuang, Chia-Ning Shen, Yong Alison Wang, An-Suei Yang
Publicado 2021

Corrigendum to “Prenatal household air pollutant exposure is associated with reduced size and gestational age at birth among a cohort of Ghanaian infants” [Environ. Int. 155 (2021)...

por Ashlinn K. Quinn, Irene Apewe Adjei, Kenneth Ayuurebobi Ae-Ngibise, Oscar Agyei, Ellen Abrafi Boamah-Kaali, Katrin Burkart, Daniel Carrión, Steven N. Chillrud, Carlos F. Gould, Stephaney Gyaase, Darby W. Jack, Seyram Kaali, Patrick L. Kinney, Alison G. Lee, Mohammed Nuhu Mujtaba, Felix Boakye Oppong, Seth Owusu-Agyei, Abena Yawson, Blair J. Wylie, Kwaku Poku Asante
Publicado 2022

A Pilot Double-Blind Placebo-Controlled Randomized Clinical Trial to Investigate the Effects of Early Enteral Nutrients in Sepsis

por Faraaz Ali Shah, MD, MPH, Georgios D. Kitsios, MD, PhD, Sachin Yende, MD, MS, Daniel G. Dunlap, MD, Denise Scholl, CRC, Byron Chuan, MS, Nameer Al-Yousif, MD, Yingze Zhang, PhD, Seyed Mehdi Nouraie, MD, PhD, Alison Morris, MD, MS, David T. Huang, MD, MPH, Christopher P. O’Donnell, PhD, Bryan J. McVerry, MD
Publicado 2021

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

por Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Publicado 2020

Genomic landscape of platinum resistant and sensitive testicular cancers

por Chey Loveday, Kevin Litchfield, Paula Z. Proszek, Alex J. Cornish, Flavia Santo, Max Levy, Geoff Macintyre, Amy Holryod, Peter Broderick, Darshna Dudakia, Barbara Benton, Maise Al Bakir, Crispin Hiley, Emily Grist, Charles Swanton, Robert Huddart, Tom Powles, Simon Chowdhury, Janet Shipley, Simon O’Connor, James D. Brenton, Alison Reid, David Gonzalez de Castro, Richard S. Houlston, Clare Turnbull
Publicado 2020

Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

por Josephine M. Forbes, Selena Le Bagge, Samuel Righi, Amelia K. Fotheringham, Linda A. Gallo, Domenica A. McCarthy, Sherman Leung, Tracey Baskerville, Janelle Nisbett, Adam Morton, Stephanie Teasdale, Neisha D’Silva, Helen Barrett, Timothy Jones, Jennifer Couper, Kim Donaghue, Nicole Isbel, David W. Johnson, Leigh Donnellan, Permal Deo, Lisa K. Akison, Karen M. Moritz, Trisha O’Moore-Sullivan
Publicado 2021

Publisher Correction: Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology

por Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publicado 2021

Ancient proteins provide evidence of dairy consumption in eastern Africa

por Madeleine Bleasdale, Kristine K. Richter, Anneke Janzen, Samantha Brown, Ashley Scott, Jana Zech, Shevan Wilkin, Ke Wang, Stephan Schiffels, Jocelyne Desideri, Marie Besse, Jacques Reinold, Mohamed Saad, Hiba Babiker, Robert C. Power, Emmanuel Ndiema, Christine Ogola, Fredrick K. Manthi, Muhammad Zahir, Michael Petraglia, Christian Trachsel, Paolo Nanni, Jonas Grossmann, Jessica Hendy, Alison Crowther, Patrick Roberts, Steven T. Goldstein, Nicole Boivin
Publicado 2021

Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation

por Alexander Roberts, Lindsay Bentley, Tina Tang, Fay Stewart, Chiara Pallini, Joel Juvvanapudi, Graham R. Wallace, Alison J. Cooper, Aaron Scott, David Thickett, Sebastian T. Lugg, Hollie Bancroft, Bridget Hemming, Charlotte Ferris, Gerald Langman, Andrew Robinson, Joanne Chapman, Babu Naidu, Thomas Pinkney, Graham S. Taylor, Kristian Brock, Zania Stamataki, Catherine A. Brady, S. John Curnow, John Gordon, Omar Qureshi, Nicholas M. Barnes
Publicado 2021