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  1. 115541
    Genome-enabled discovery of anthraquinone biosynthesis in Senna tora
    “..., but the biosynthetic pathway is unclear. Here, the authors assemble the genome of an anthraquinone-producing medicinal...”
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  2. 115542
    Copper-catalyzed carbo-difluoromethylation of alkenes via radical relay
    “...Compounds that contain alkyl-difluoromethyl moieties are of interest for medicinal chemistry...”
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  3. 115543
    Immunostimulatory properties of heat-resistant RNA in a decoction of Glycyrrhizae Radix
    “...Research on the bioactive components of herbal medicines have been conducted mainly...”
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  4. 115544
    Investigación y desarrollo de nuevos medicamentos: de la molécula al fármaco
    por Marovac,Jacqueline
    Publicado 2001
    “... effectiveness and safety. There are three large administrators of medicines that control the process of new drug...”
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  5. 115545
    Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids
    “...Coptis chinensis represents an early-diverging eudicot lineage with diverse medicinal applications...”
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  6. 115546
    A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission
    “... medicinal chemistry approach, Baker et al. generate an imidazopyridine that selectively targets Plasmodium...”
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  7. 115547
    Regioselective Markovnikov hydrodifluoroalkylation of alkenes using difluoroenoxysilanes
    “...Alkene hydrodifluoroalkylation is a fruitful strategy for synthesizing medicinally relevant...”
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  8. 115548
    The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis
    “... in plants. Here, the authors describe triterpenoid synthesis as mediated by CYP716 enzymes in medicinal...”
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  9. 115549
    A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
    por Paul M. O’Neill, Richard K. Amewu, Susan A. Charman, Sunil Sabbani, Nina F. Gnädig, Judith Straimer, David A. Fidock, Emma R. Shore, Natalie L. Roberts, Michael H.-L. Wong, W. David Hong, Chandrakala Pidathala, Chris Riley, Ben Murphy, Ghaith Aljayyoussi, Francisco Javier Gamo, Laura Sanz, Janneth Rodrigues, Carolina Gonzalez Cortes, Esperanza Herreros, Iñigo Angulo-Barturén, María Belén Jiménez-Díaz, Santiago Ferrer Bazaga, María Santos Martínez-Martínez, Brice Campo, Raman Sharma, Eileen Ryan, David M. Shackleford, Simon Campbell, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, Ric N. Price, Jutta Marfurt, Michael J. Palmer, Ian M. Copple, Amy E. Mercer, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Peter Siegl, Jill Davies, Rosemary Rochford, Clemens H. M. Kocken, Anne-Marie Zeeman, Gemma L. Nixon, Giancarlo A. Biagini, Stephen A. Ward
    Publicado 2017
    “...Artemisinin-resistantPlasmodium is an increasing problem. Here, using a medicinal chemistry...”
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  10. 115550
    Multidirectional desymmetrization of pluripotent building block en route to diastereoselective synthesis of complex nature-inspired scaffolds
    “... medicinal use are sought after in drug design. Here, the authors report a build/couple/pair strategy...”
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  11. 115551
    FINANCIAL ANALYSIS OF PHARMACEUTICAL COMPANIES
    por E. Sedova, A. Chechulina
    Publicado 2016
    “...In the article the observed factors affecting the production of medicines, as well as indicate what...”
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  12. 115552
    Synthesis of difluoromethylated allenes through trifunctionalization of 1,3-enynes
    “...Fluorinated or fluoroalkylated allenes are versatile building blocks for medicinal and material...”
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  13. 115553
    SC83288 is a clinical development candidate for the treatment of severe malaria
    “... medicinal chemistry approach starting from amicarbalide, Pegoraroet al. identify a compound that, when...”
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  14. 115554
    A Comprehensive Study of the Genus <i>Sanguisorba</i> (Rosaceae) Based on the Floral Micromorphology, Palynology, and Plastome Analysis
    “...>S. tenuifolia</i>. <i>S. officinalis</i> has been designated as a medicinal remedy in the Chinese and Korean...”
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  15. 115555
    Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole
    “...-Myers Squibb, Princeton, NJ, USABackground: Many medicines, including several cholesterol-lowering...”
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  16. 115556
    Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions
    “... azetidines, which are common medicinal scaffolds. Here, the authors report a mild and selective visible light...”
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  17. 115557
    Arylmethylamino steroids as antiparasitic agents
    “... medicinal chemistry program, Krieget al. identify an arylmethylamino steroid that kills Plasmodium parasites...”
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  18. 115558
    Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis
    “...Ophiorrhiza pumila is a medicinal plant that can produce the anti-cancer monoterpene indole...”
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  19. 115559
    Late-stage trifluoromethylthiolation of benzylic C-H bonds
    “...Fluoroalkylation of C-H bonds is a class of reaction highly sought after in medicinal chemistry...”
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  20. 115560
    Synthetic biology 2020–2030: six commercially-available products that are changing our world
    por Christopher A. Voigt
    Publicado 2020
    “... and medicines. Here I have selected six products that are now on the market, highlighting the underlying...”
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