An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells

por Maikel L. Colli, Mireia Ramos-Rodríguez, Ernesto S. Nakayasu, Maria I. Alvelos, Miguel Lopes, Jessica L. E. Hill, Jean-Valery Turatsinze, Alexandra Coomans de Brachène, Mark A. Russell, Helena Raurell-Vila, Angela Castela, Jonàs Juan-Mateu, Bobbie-Jo M. Webb-Robertson, Lars Krogvold, Knut Dahl-Jorgensen, Lorella Marselli, Piero Marchetti, Sarah J. Richardson, Noel G. Morgan, Thomas O. Metz, Lorenzo Pasquali, Décio L. Eizirik
Publicado 2020

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

por Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publicado 2020

The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): protocol for a prospective longitudinal cohort study of healthcare and anci...

por Laura J Gray, Luke Bryant, Robert C Free, Fatimah Wobi, Amit Gupta, Catherine John, Martin D Tobin, Chris Orton, Sue Carr, David Ford, Keith Abrams, Martin Tobin, Lucy Teece, Carl Melbourne, Edward Dove, Mayuri Gogoi, Ruby Reed-Berendt, Amani Al-Oraibi, Osama Hassan, Anna L Guyatt, I Chris McManus, Claire Garwood, Vishant Modhwadia, Ian Chris McManus, Janet Hood
Publicado 2021

Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens.

por Matthew T G Holden, Zoe Heather, Romain Paillot, Karen F Steward, Katy Webb, Fern Ainslie, Thibaud Jourdan, Nathalie C Bason, Nancy E Holroyd, Karen Mungall, Michael A Quail, Mandy Sanders, Mark Simmonds, David Willey, Karen Brooks, David M Aanensen, Brian G Spratt, Keith A Jolley, Martin C J Maiden, Michael Kehoe, Neil Chanter, Stephen D Bentley, Carl Robinson, Duncan J Maskell, Julian Parkhill, Andrew S Waller
Publicado 2009

A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization

por Jue-Sheng Ong, Suzanne C. Dixon-Suen, Xikun Han, Jiyuan An, Esophageal Cancer Consortium, 23 and Me Research Team, Upekha Liyanage, Jean-Cluade Dusingize, Johannes Schumacher, Ines Gockel, Anne Böhmer, Janusz Jankowski, Claire Palles, Tracy O’Mara, Amanda Spurdle, Matthew H. Law, Mark M. Iles, Paul Pharoah, Andrew Berchuck, Wei Zheng, Aaron P. Thrift, Catherine Olsen, Rachel E. Neale, Puya Gharahkhani, Penelope M. Webb, Stuart MacGregor
Publicado 2021

Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses

por Vineet D. Menachery, Amie J. Eisfeld, Alexandra Schäfer, Laurence Josset, Amy C. Sims, Sean Proll, Shufang Fan, Chengjun Li, Gabriele Neumann, Susan C. Tilton, Jean Chang, Lisa E. Gralinski, Casey Long, Richard Green, Christopher M. Williams, Jeffrey Weiss, Melissa M. Matzke, Bobbie-Jo Webb-Robertson, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Richard D. Smith, Katrina M. Waters, Michael G. Katze, Yoshihiro Kawaoka, Ralph S. Baric
Publicado 2014

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques

por Benjamin J. Burwitz, Jochen M. Wettengel, Martin A. Mück-Häusl, Marc Ringelhan, Chunkyu Ko, Marvin M. Festag, Katherine B. Hammond, Mina Northrup, Benjamin N. Bimber, Thomas Jacob, Jason S. Reed, Reed Norris, Byung Park, Sven Moller-Tank, Knud Esser, Justin M. Greene, Helen L. Wu, Shaheed Abdulhaqq, Gabriela Webb, William F. Sutton, Alex Klug, Tonya Swanson, Alfred W. Legasse, Tania Q. Vu, Aravind Asokan, Nancy L. Haigwood, Ulrike Protzer, Jonah B. Sacha
Publicado 2017

Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy

por Jennifer Friedman, Desiree E. Smith, Mahmoud Y. Issa, Valentina Stanley, Rengang Wang, Marisa I. Mendes, Meredith S. Wright, Kristen Wigby, Amber Hildreth, John R. Crawford, Alanna E. Koehler, Shimul Chowdhury, Shareef Nahas, Liting Zhai, Zhiwen Xu, Wing-Sze Lo, Kiely N. James, Damir Musaev, Andrea Accogli, Kether Guerrero, Luan T. Tran, Tarek E. I. Omar, Tawfeg Ben-Omran, David Dimmock, Stephen F. Kingsmore, Gajja S. Salomons, Maha S. Zaki, Geneviève Bernard, Joseph G. Gleeson
Publicado 2019

Characteristics and Outcome of Severe Mycoplasma pneumoniae Pneumonia Admitted to PICU in Shanghai: A Retrospective Cohort Study

por Yiping Zhou, MD, Yijun Shan, MD, Yun Cui, MD, Jingyi Shi, MD, PhD, Fei Wang, MD, Huijie Miao, MD, Chunxia Wang, PhD, Yucai Zhang, PhD, Hari Krishnan Kanthimathinathan, Roddy O’Donnell, Michelle Jardine, Jo Lumsden, Jeremy Tong, Anand Wagh, Pascale du Pre, Andrew Nyman, Bogdana Zoica, Rachel Neal, Rebecca Mitting, Konstantinos Dimitraides, Claire Jennings, Karen Coxon, Charlotte Goedvolk, James Weitz, Jade Bryant, Jillian MacFadzean, Alastair Turner
Publicado 2021

Experimental discrimination of ion stopping models near the Bragg peak in highly ionized matter

por W. Cayzac, A. Frank, A. Ortner, V. Bagnoud, M. M. Basko, S. Bedacht, C. Bläser, A. Blažević, S. Busold, O. Deppert, J. Ding, M. Ehret, P. Fiala, S. Frydrych, D. O. Gericke, L. Hallo, J. Helfrich, D. Jahn, E. Kjartansson, A. Knetsch, D. Kraus, G. Malka, N. W. Neumann, K. Pépitone, D. Pepler, S. Sander, G. Schaumann, T. Schlegel, N. Schroeter, D. Schumacher, M. Seibert, An. Tauschwitz, J. Vorberger, F. Wagner, S. Weih, Y. Zobus, M. Roth
Publicado 2017

Immune checkpoint modulation enhances HIV-1 antibody induction

por Todd Bradley, Masayuki Kuraoka, Chen-Hao Yeh, Ming Tian, Huan Chen, Derek W. Cain, Xuejun Chen, Cheng Cheng, Ali H. Ellebedy, Robert Parks, Maggie Barr, Laura L. Sutherland, Richard M. Scearce, Cindy M. Bowman, Hilary Bouton-Verville, Sampa Santra, Kevin Wiehe, Mark G. Lewis, Ane Ogbe, Persephone Borrow, David Montefiori, Mattia Bonsignori, M. Anthony Moody, Laurent Verkoczy, Kevin O. Saunders, Rafi Ahmed, John R. Mascola, Garnett Kelsoe, Frederick W. Alt, Barton F. Haynes
Publicado 2020

VDAC2 enables BAX to mediate apoptosis and limit tumor development

por Hui San Chin, Mark X. Li, Iris K. L. Tan, Robert L. Ninnis, Boris Reljic, Kristen Scicluna, Laura F. Dagley, Jarrod J. Sandow, Gemma L. Kelly, Andre L. Samson, Stephane Chappaz, Seong L. Khaw, Catherine Chang, Andrew Morokoff, Kerstin Brinkmann, Andrew Webb, Colin Hockings, Cathrine M. Hall, Andrew J. Kueh, Michael T. Ryan, Ruth M. Kluck, Philippe Bouillet, Marco J. Herold, Daniel H. D. Gray, David C. S. Huang, Mark F. van Delft, Grant Dewson
Publicado 2018

Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes

por Benjamin J. Burwitz, Helen L. Wu, Shaheed Abdulhaqq, Christine Shriver-Munsch, Tonya Swanson, Alfred W. Legasse, Katherine B. Hammond, Stephanie L. Junell, Jason S. Reed, Benjamin N. Bimber, Justin M. Greene, Gabriela M. Webb, Mina Northrup, Wolfram Laub, Paul Kievit, Rhonda MacAllister, Michael K. Axthelm, Rebecca Ducore, Anne Lewis, Lois M. A. Colgin, Theodore Hobbs, Lauren D. Martin, Betsy Ferguson, Charles R. Thomas Jr., Angela Panoskaltsis-Mortari, Gabrielle Meyers, Jeffrey J. Stanton, Richard T. Maziarz, Jonah B. Sacha
Publicado 2017

SARS-CoV-2 detection using reverse transcription strand invasion based amplification and a portable compact size instrument

por Maiken W. Rosenstierne, Shreya Joshi, E. Thomas Danielsen, Helen Webb, Dac Mui Luong, Julie Bjerring, Julie Hindkær, Lærke Jørgensen, Julie Blauenfeldt, Ask Bojesen, Flemming Holck, Johnny Weber Lau, Lars Bangsgaard, Jakob Broberg Lind, Mette Bjergaard Dragheim, Mikkel Rohde Jacobsen, Robert Elkjær, Steven Clauwaert, Kristina Christensen, Charlotta Polacek, Anders Fomsgaard, Tuomas Ojalehto, Antti Tullila, Mirko Brummer, Claus Juel Jensen, Frederikke Holm Jensen, Uffe Vest Schneider, Jan Gorm Lisby, Rikke Lind Jørgensen, Thomas Warthoe, Ebbe Finding, Peter Warthoe
Publicado 2021

Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

por Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publicado 2021

Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients

por Kimberley Allen-Philbey, Stefania De Trane, Zhifeng Mao, Cesar Álvarez-González, Joela Mathews, Amy MacDougall, Andrea Stennett, Xia Zhou, Ozlem Yildiz, Ashok Adams, Lucia Bianchi, Camilla Blain, Christine Chapman, Karen Chung, Cris S Constantinescu, Catherine Dalton, Rachel A Farrell, Leonora Fisniku, Helen Ford, Bruno Gran, Jeremy Hobart, Zhaleh Khaleeli, Miriam Mattoscio, Sue Pavitt, Owen Pearson, Luca Peruzzotti-Jametti, Antonio Scalfari, Basil Sharrack, Eli Silber, Emma C Tallantyre, Stewart Webb, Benjamin P Turner, Monica Marta, Sharmilee Gnanapavan, Gunnar Juliusson, Gavin Giovannoni, David Baker, Klaus Schmierer
Publicado 2021