Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer

por Svitlana Tyekucheva, Michaela Bowden, Clyde Bango, Francesca Giunchi, Ying Huang, Chensheng Zhou, Arrigo Bondi, Rosina Lis, Mieke Van Hemelrijck, Ove Andrén, Sven-Olof Andersson, R. William Watson, Stephen Pennington, Stephen P. Finn, Neil E. Martin, Meir J. Stampfer, Giovanni Parmigiani, Kathryn L. Penney, Michelangelo Fiorentino, Lorelei A. Mucci, Massimo Loda
Publicado 2017

TET-mediated epimutagenesis of the Arabidopsis thaliana methylome

por Lexiang Ji, William T. Jordan, Xiuling Shi, Lulu Hu, Chuan He, Robert J. Schmitz
Publicado 2018

Surface-wave-assisted nonreciprocity in spatio-temporally modulated metasurfaces

por Andrew E. Cardin, Sinhara R. Silva, Shai R. Vardeny, Willie J. Padilla, Avadh Saxena, Antoinette J. Taylor, Wilton J. M. Kort-Kamp, Hou-Tong Chen, Diego A. R. Dalvit, Abul K. Azad
Publicado 2020

Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

por Inês Sequeira, Mamunur Rashid, Inês M. Tomás, Marc J. Williams, Trevor A. Graham, David J. Adams, Alessandra Vigilante, Fiona M. Watt
Publicado 2020

MEKK2 mediates aberrant ERK activation in neurofibromatosis type I

por Seoyeon Bok, Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu, Na Li, Jun Sun, Alfred L. Williams, John E. Scott, Bing Su, Jae-Hyuck Shim, Matthew B. Greenblatt
Publicado 2020

Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle

por Wai Yee Low, Rick Tearle, Ruijie Liu, Sergey Koren, Arang Rhie, Derek M. Bickhart, Benjamin D. Rosen, Zev N. Kronenberg, Sarah B. Kingan, Elizabeth Tseng, Françoise Thibaud-Nissen, Fergal J. Martin, Konstantinos Billis, Jay Ghurye, Alex R. Hastie, Joyce Lee, Andy W. C. Pang, Michael P. Heaton, Adam M. Phillippy, Stefan Hiendleder, Timothy P. L. Smith, John L. Williams
Publicado 2020

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast

por Ali R. Awan, Benjamin A. Blount, David J. Bell, William M. Shaw, Jack C.H. Ho, Robert M. McKiernan, Tom Ellis
Publicado 2017

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

por Farnaz Shamsi, Ruidan Xue, Tian Lian Huang, Morten Lundh, Yang Liu, Luiz O. Leiria, Matthew D. Lynes, Elena Kempf, Chih-Hao Wang, Satoru Sugimoto, Pasquale Nigro, Kathrin Landgraf, Tim Schulz, Yiming Li, Brice Emanuelli, Srinivas Kothakota, Lewis T. Williams, Niels Jessen, Steen Bønløkke Pedersen, Yvonne Böttcher, Matthias Blüher, Antje Körner, Laurie J. Goodyear, Moosa Mohammadi, C. Ronald Kahn, Yu-Hua Tseng
Publicado 2020

Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell

por Miklos Bagdany, Guido Veit, Ryosuke Fukuda, Radu G. Avramescu, Tsukasa Okiyoneda, Imad Baaklini, Jay Singh, Guy Sovak, Haijin Xu, Pirjo M. Apaja, Sara Sattin, Lenore K. Beitel, Ariel Roldan, Giorgio Colombo, William Balch, Jason C. Young, Gergely L. Lukacs
Publicado 2017

Multiplexed single-mode wavelength-to-time mapping of multimode light

por Harikumar K Chandrasekharan, Frauke Izdebski, Itandehui Gris-Sánchez, Nikola Krstajić, Richard Walker, Helen L. Bridle, Paul A. Dalgarno, William N. MacPherson, Robert K. Henderson, Tim A. Birks, Robert R. Thomson
Publicado 2017

Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

por Kahia Messaoudi, Ashfaq Ali, Rameez Ishaq, Alberta Palazzo, Dominika Sliwa, Olivier Bluteau, Sylvie Souquère, Delphine Muller, Khadija M. Diop, Philippe Rameau, Valérie Lapierre, Jean-Pierre Marolleau, Patrick Matthias, Isabelle Godin, Gérard Pierron, Steven G. Thomas, Stephen P. Watson, Nathalie Droin, William Vainchenker, Isabelle Plo, Hana Raslova, Najet Debili
Publicado 2017

Domestication via the commensal pathway in a fish-invertebrate mutualism

por Rohan M. Brooker, Jordan M. Casey, Zara-Louise Cowan, Tiffany L. Sih, Danielle L. Dixson, Andrea Manica, William E. Feeney
Publicado 2020

Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

por Joonas A. Jamsen, William A. Beard, Lars C. Pedersen, David D. Shock, Andrea F. Moon, Juno M. Krahn, Katarzyna Bebenek, Thomas A. Kunkel, Samuel H. Wilson
Publicado 2017

Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction

por Florian Fäßler, Georgi Dimchev, Victor-Valentin Hodirnau, William Wan, Florian K. M. Schur
Publicado 2020

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

por Anoushka Joglekar, Andrey Prjibelski, Ahmed Mahfouz, Paul Collier, Susan Lin, Anna Katharina Schlusche, Jordan Marrocco, Stephen R. Williams, Bettina Haase, Ashley Hayes, Jennifer G. Chew, Neil I. Weisenfeld, Man Ying Wong, Alexander N. Stein, Simon A. Hardwick, Toby Hunt, Qi Wang, Christoph Dieterich, Zachary Bent, Olivier Fedrigo, Steven A. Sloan, Davide Risso, Erich D. Jarvis, Paul Flicek, Wenjie Luo, Geoffrey S. Pitt, Adam Frankish, August B. Smit, M. Elizabeth Ross, Hagen U. Tilgner
Publicado 2021

Disulfide disruption reverses mucus dysfunction in allergic airway disease

por Leslie E. Morgan, Ana M. Jaramillo, Siddharth K. Shenoy, Dorota Raclawska, Nkechinyere A. Emezienna, Vanessa L. Richardson, Naoko Hara, Anna Q. Harder, James C. NeeDell, Corinne E. Hennessy, Hassan M. El-Batal, Chelsea M. Magin, Diane E. Grove Villalon, Gregg Duncan, Justin S. Hanes, Jung Soo Suk, David J. Thornton, Fernando Holguin, William J. Janssen, William R. Thelin, Christopher M. Evans
Publicado 2021

Prediction of lithium response using genomic data

por William Stone, Abraham Nunes, Kazufumi Akiyama, Nirmala Akula, Raffaella Ardau, Jean-Michel Aubry, Lena Backlund, Michael Bauer, Frank Bellivier, Pablo Cervantes, Hsi-Chung Chen, Caterina Chillotti, Cristiana Cruceanu, Alexandre Dayer, Franziska Degenhardt, Maria Del Zompo, Andreas J. Forstner, Mark Frye, Janice M. Fullerton, Maria Grigoroiu-Serbanescu, Paul Grof, Ryota Hashimoto, Liping Hou, Esther Jiménez, Tadafumi Kato, John Kelsoe, Sarah Kittel-Schneider, Po-Hsiu Kuo, Ichiro Kusumi, Catharina Lavebratt, Mirko Manchia, Lina Martinsson, Manuel Mattheisen, Francis J. McMahon, Vincent Millischer, Philip B. Mitchell, Markus M. Nöthen, Claire O’Donovan, Norio Ozaki, Claudia Pisanu, Andreas Reif, Marcella Rietschel, Guy Rouleau, Janusz Rybakowski, Martin Schalling, Peter R. Schofield, Thomas G. Schulze, Giovanni Severino, Alessio Squassina, Julia Veeh, Eduard Vieta, Thomas Trappenberg, Martin Alda
Publicado 2021

BRD4-mediated repression of p53 is a target for combination therapy in AML

por Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil A. Robertson, Xue Lei, Helen J. S. Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-ichi Sakamaki, Jennifer P. Morton, Kevin M. Ryan, Stephen W. G. Tait, Sheela A. Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J. T. Chevassut, Karen Keeshan, Peter D. Adams
Publicado 2021

Quantile-specific heritability of sibling leptin concentrations and its implications for gene-environment interactions

por Paul T. Williams
Publicado 2020

Risk factors and knowledge associated with high unintended pregnancy rates and low family planning use among pregnant women in Papua New Guinea

por Elizabeth Peach, Christopher Morgan, Michelle J. L. Scoullar, Freya J. I. Fowkes, Elissa Kennedy, Pele Melepia, Primrose Homiehombo, Lucy Au, Stanley Luchters, Alexandra J. Umbers, Andrew Vallely, Lisa M. Vallely, Angela Kelly-Hanku, Leanne J. Robinson, Brendan S. Crabb, Arthur Elijah, Peter M. Siba, William Pomat, James G. Beeson
Publicado 2021