Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML

por Thomas Oellerich, Constanze Schneider, Dominique Thomas, Kirsten M. Knecht, Olga Buzovetsky, Lars Kaderali, Christoph Schliemann, Hanibal Bohnenberger, Linus Angenendt, Wolfgang Hartmann, Eva Wardelmann, Tamara Rothenburger, Sebastian Mohr, Sebastian Scheich, Federico Comoglio, Anne Wilke, Philipp Ströbel, Hubert Serve, Martin Michaelis, Nerea Ferreirós, Gerd Geisslinger, Yong Xiong, Oliver T. Keppler, Jindrich Cinatl
Publicado 2019

Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density

por Alessandra Chesi, Yadav Wagley, Matthew E. Johnson, Elisabetta Manduchi, Chun Su, Sumei Lu, Michelle E. Leonard, Kenyaita M. Hodge, James A. Pippin, Kurt D. Hankenson, Andrew D. Wells, Struan F. A. Grant
Publicado 2019

Role of defects in determining the magnetic ground state of ytterbium titanate

por D. F. Bowman, E. Cemal, T. Lehner, A. R. Wildes, L. Mangin-Thro, G. J. Nilsen, M. J. Gutmann, D. J. Voneshen, D. Prabhakaran, A. T. Boothroyd, D. G. Porter, C. Castelnovo, K. Refson, J. P. Goff
Publicado 2019

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling

por Xia Sheng, Hatice Zeynep Nenseth, Su Qu, Omer F. Kuzu, Turid Frahnow, Lukas Simon, Stephanie Greene, Qingping Zeng, Ladan Fazli, Paul S. Rennie, Ian G. Mills, Håvard Danielsen, Fabian Theis, John B. Patterson, Yang Jin, Fahri Saatcioglu
Publicado 2019

Correction: Corrigendum: Alternative futures for Borneo show the value of integrating economic and conservation targets across borders

por Rebecca K. Runting, Erik Meijaard, Nicola K. Abram, Jessie A. Wells, David L. A. Gaveau, Marc Ancrenaz, Hugh P. Possingham, Serge A. Wich, Fitrian Ardiansyah, Melvin T. Gumal, Laurentius N. Ambu, Kerrie A. Wilson
Publicado 2016

A highly-contiguous genome assembly of the Eurasian spruce bark beetle, Ips typographus, provides insight into a major forest pest

por Daniel Powell, Ewald Groβe-Wilde, Paal Krokene, Amit Roy, Amrita Chakraborty, Christer Löfstedt, Heiko Vogel, Martin N. Andersson, Fredrik Schlyter
Publicado 2021

An omics-based framework for assessing the health risk of antimicrobial resistance genes

por An-Ni Zhang, Jeffry M. Gaston, Chengzhen L. Dai, Shijie Zhao, Mathilde Poyet, Mathieu Groussin, Xiaole Yin, Li-Guan Li, Mark C. M. van Loosdrecht, Edward Topp, Michael R. Gillings, William P. Hanage, James M. Tiedje, Katya Moniz, Eric J. Alm, Tong Zhang
Publicado 2021

Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism

por Yuta Horie, Takafumi Suzuki, Jin Inoue, Tatsuro Iso, Geoffrey Wells, Terry W. Moore, Tsunehiro Mizushima, Albena T. Dinkova-Kostova, Takuma Kasai, Takashi Kamei, Seizo Koshiba, Masayuki Yamamoto
Publicado 2021

Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase

por M. C. Wilkes, K. Siva, J. Chen, G. Varetti, M. Y. Youn, H. Chae, F. Ek, R. Olsson, T. Lundbäck, D. P. Dever, T. Nishimura, A. Narla, B. Glader, H. Nakauchi, M. H. Porteus, C. E. Repellin, H. T. Gazda, S. Lin, M. Serrano, J. Flygare, K. M. Sakamoto
Publicado 2020

Mimicking Paracrine TGFβ1 Signals during Myofibroblast Differentiation in 3D Collagen Networks

por Michael Ansorge, Jiranuwat Sapudom, Marina Chkolnikov, Martin Wilde, Ulf Anderegg, Stephanie Möller, Matthias Schnabelrauch, Tilo Pompe
Publicado 2017

Correction: Corrigendum: CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes

por Emma C. Mackley, Stephanie Houston, Clare L. Marriott, Emily E. Halford, Beth Lucas, Vuk Cerovic, Kara J. Filbey, Rick M. Maizels, Matthew R. Hepworth, Gregory F. Sonnenberg, Simon Milling, David R. Withers
Publicado 2016

Immuno-genomic landscape of osteosarcoma

por Chia-Chin Wu, Hannah C. Beird, J. Andrew Livingston, Shailesh Advani, Akash Mitra, Shaolong Cao, Alexandre Reuben, Davis Ingram, Wei-Lien Wang, Zhenlin Ju, Cheuk Hong Leung, Heather Lin, Youyun Zheng, Jason Roszik, Wenyi Wang, Shreyaskumar Patel, Robert S. Benjamin, Neeta Somaiah, Anthony P. Conley, Gordon B. Mills, Patrick Hwu, Richard Gorlick, Alexander Lazar, Najat C. Daw, Valerae Lewis, P. Andrew Futreal
Publicado 2020

Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

por Vincenza Cifarelli, Sila Appak-Baskoy, Vivek S. Peche, Andrew Kluzak, Trevor Shew, Ramkumar Narendran, Kathryn M. Pietka, Marina Cella, Curtis W. Walls, Rafael Czepielewski, Stoyan Ivanov, Gwendalyn J. Randolph, Hellmut G. Augustin, Nada A. Abumrad
Publicado 2021

A methylated lysine is a switch point for conformational communication in the chaperone Hsp90

por Alexandra Rehn, Jannis Lawatscheck, Marie-Lena Jokisch, Sophie L. Mader, Qi Luo, Franziska Tippel, Birgit Blank, Klaus Richter, Kathrin Lang, Ville R. I. Kaila, Johannes Buchner
Publicado 2020

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

por Ellis Chika Onwordi, Els F. Halff, Thomas Whitehurst, Ayla Mansur, Marie-Caroline Cotel, Lisa Wells, Hannah Creeney, David Bonsall, Maria Rogdaki, Ekaterina Shatalina, Tiago Reis Marques, Eugenii A. Rabiner, Roger N. Gunn, Sridhar Natesan, Anthony C. Vernon, Oliver D. Howes
Publicado 2020

Pillar-beam structures prevent layered cathode materials from destructive phase transitions

por Yuesheng Wang, Zimin Feng, Peixin Cui, Wen Zhu, Yue Gong, Marc-André Girard, Gilles Lajoie, Julie Trottier, Qinghua Zhang, Lin Gu, Yan Wang, Wenhua Zuo, Yong Yang, John B. Goodenough, Karim Zaghib
Publicado 2021

Uranium(III)-carbon multiple bonding supported by arene δ-bonding in mixed-valence hexauranium nanometre-scale rings

por Ashley J. Wooles, David P. Mills, Floriana Tuna, Eric J. L. McInnes, Gareth T. W. Law, Adam J. Fuller, Felipe Kremer, Mark Ridgway, William Lewis, Laura Gagliardi, Bess Vlaisavljevich, Stephen T. Liddle
Publicado 2018

Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer

por Julien Baruteau, Dany P. Perocheau, Joanna Hanley, Maëlle Lorvellec, Eridan Rocha-Ferreira, Rajvinder Karda, Joanne Ng, Natalie Suff, Juan Antinao Diaz, Ahad A. Rahim, Michael P. Hughes, Blerida Banushi, Helen Prunty, Mariya Hristova, Deborah A. Ridout, Alex Virasami, Simon Heales, Stewen J. Howe, Suzanne M. K. Buckley, Philippa B. Mills, Paul Gissen, Simon N. Waddington
Publicado 2018

A constraint programming primer

por Gilles Pesant
Publicado 2014

Should I stay, or should I go?

por Sarah Silverberg
Publicado 2019