A molecular mechanism for bacterial susceptibility to zinc.

by Christopher A McDevitt, Abiodun D Ogunniyi, Eugene Valkov, Michael C Lawrence, Bostjan Kobe, Alastair G McEwan, James C Paton
Published 2011

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by <italic toggle="yes">Streptococcus pneumoniae</italic>, Resulting in Hypervirulence

by Claudia Trappetti, Lauren J. McAllister, Austen Chen, Hui Wang, Adrienne W. Paton, Marco R. Oggioni, Christopher A. McDevitt, James C. Paton
Published 2017

Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in Streptococcus pneumoniae.

by Bart A Eijkelkamp, Jacqueline R Morey, Miranda P Ween, Cheryl-lynn Y Ong, Alastair G McEwan, James C Paton, Christopher A McDevitt
Published 2014

Experimental Evolution <italic toggle="yes">In Vivo</italic> To Identify Selective Pressures during Pneumococcal Colonization

by Vaughn S. Cooper, Erin Honsa, Hannah Rowe, Christopher Deitrick, Amy R. Iverson, Jonathan J. Whittall, Stephanie L. Neville, Christopher A. McDevitt, Colin Kietzman, Jason W. Rosch
Published 2020

The Metallophore Staphylopine Enables <italic toggle="yes">Staphylococcus aureus</italic> To Compete with the Host for Zinc and Overcome Nutritional Immunity

by Kyle P. Grim, Brian San Francisco, Jana N. Radin, Erin B. Brazel, Jessica L. Kelliher, Paola K. Párraga Solórzano, Philip C. Kim, Christopher A. McDevitt, Thomas E. Kehl-Fie
Published 2017

Identification of Novel <italic toggle="yes">Acinetobacter baumannii</italic> Host Fatty Acid Stress Adaptation Strategies

by Jhih-Hang Jiang, Karl A. Hassan, Stephanie L. Begg, Thusitha W. T. Rupasinghe, Varsha Naidu, Victoria G. Pederick, Marjan Khorvash, Jonathan J. Whittall, James C. Paton, Ian T. Paulsen, Christopher A. McDevitt, Anton Y. Peleg, Bart A. Eijkelkamp
Published 2019

A Trap-Door Mechanism for Zinc Acquisition by <i>Streptococcus pneumoniae</i> AdcA

by Zhenyao Luo, Jacqueline R. Morey, Evelyne Deplazes, Alina Motygullina, Aimee Tan, Katherine Ganio, Stephanie L. Neville, Nikolaos Eleftheriadis, Michael Isselstein, Victoria G. Pederick, James C. Paton, Thorben Cordes, Jeffrey R. Harmer, Bostjan Kobe, Christopher A. McDevitt
Published 2021

Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2

by Nichaela Harbison-Price, Scott A. Ferguson, Adam Heikal, George Taiaroa, Kiel Hards, Yoshio Nakatani, David Rennison, Margaret A. Brimble, Ibrahim M. El-Deeb, Lisa Bohlmann, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker, Gregory M. Cook
Published 2020

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

by Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Published 2019

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

by Lisa Bohlmann, David M. P. De Oliveira, Ibrahim M. El-Deeb, Erin B. Brazel, Nichaela Harbison-Price, Cheryl-lynn Y. Ong, Tania Rivera-Hernandez, Scott A. Ferguson, Amanda J. Cork, Minh-Duy Phan, Amelia T. Soderholm, Mark R. Davies, Graeme R. Nimmo, Gordon Dougan, Mark A. Schembri, Gregory M. Cook, Alastair G. McEwan, Mark von Itzstein, Christopher A. McDevitt, Mark J. Walker
Published 2018