The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design

par Larissa Dirr, Ibrahim M. El-Deeb, Leonard M. G. Chavas, Patrice Guillon, Mark von Itzstein
Publié 2017

Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions

par Christopher J. Day, Benjamin Bailly, Patrice Guillon, Larissa Dirr, Freda E.-C. Jen, Belinda L. Spillings, Johnson Mak, Mark von Itzstein, Thomas Haselhorst, Michael P. Jennings
Publié 2021

Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia

par Somayeh S. Tarighat, Fei Fei, Eun Ji Joo, Hisham Abdel-Azim, Lu Yang, Huimin Geng, Khuchtumur Bum-Erdene, I. Darren Grice, Mark von Itzstein, Helen Blanchard, Nora Heisterkamp
Publié 2021

Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2

par Nichaela Harbison-Price, Scott A. Ferguson, Adam Heikal, George Taiaroa, Kiel Hards, Yoshio Nakatani, David Rennison, Margaret A. Brimble, Ibrahim M. El-Deeb, Lisa Bohlmann, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker, Gregory M. Cook
Publié 2020

Neutralizing the pathological effects of extracellular histones with small polyanions

par Connor H. O’ Meara, Lucy A. Coupland, Farzaneh Kordbacheh, Benjamin J. C. Quah, Chih-Wei Chang, David A. Simon Davis, Anna Bezos, Anna M. Browne, Craig Freeman, Dillon J. Hammill, Pradeep Chopra, Gergely Pipa, Paul D. Madge, Esther Gallant, Courtney Segovis, Angela F. Dulhunty, Leonard F. Arnolda, Imogen Mitchell, Levon M. Khachigian, Ross W. Stephens, Mark von Itzstein, Christopher R. Parish
Publié 2020

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

par Lisa Bohlmann, David M. P. De Oliveira, Ibrahim M. El-Deeb, Erin B. Brazel, Nichaela Harbison-Price, Cheryl-lynn Y. Ong, Tania Rivera-Hernandez, Scott A. Ferguson, Amanda J. Cork, Minh-Duy Phan, Amelia T. Soderholm, Mark R. Davies, Graeme R. Nimmo, Gordon Dougan, Mark A. Schembri, Gregory M. Cook, Alastair G. McEwan, Mark von Itzstein, Christopher A. McDevitt, Mark J. Walker
Publié 2018