A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern

par Mitch Brinkkemper, Philip J. M. Brouwer, Pauline Maisonnasse, Marloes Grobben, Tom G. Caniels, Meliawati Poniman, Judith A. Burger, Ilja Bontjer, Melissa Oomen, Joey H. Bouhuijs, Cynthia A. van der Linden, Julien Villaudy, Yme U. van der Velden, Kwinten Sliepen, Marit J. van Gils, Roger Le Grand, Rogier W. Sanders
Publié 2021

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies.

par Rogier W Sanders, Ronald Derking, Albert Cupo, Jean-Philippe Julien, Anila Yasmeen, Natalia de Val, Helen J Kim, Claudia Blattner, Alba Torrents de la Peña, Jacob Korzun, Michael Golabek, Kevin de Los Reyes, Thomas J Ketas, Marit J van Gils, C Richter King, Ian A Wilson, Andrew B Ward, P J Klasse, John P Moore
Publié 2013

Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.

par Jelle van Schooten, Marlies M van Haaren, Hui Li, Laura E McCoy, Colin Havenar-Daughton, Christopher A Cottrell, Judith A Burger, Patricia van der Woude, Leanne C Helgers, Ilhan Tomris, Celia C Labranche, David C Montefiori, Andrew B Ward, Dennis R Burton, John P Moore, Rogier W Sanders, Shane Crotty, George M Shaw, Marit J van Gils
Publié 2021

Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles

par Philip J. M. Brouwer, Aleksandar Antanasijevic, Marlon de Gast, Joel D. Allen, Tom P. L. Bijl, Anila Yasmeen, Rashmi Ravichandran, Judith A. Burger, Gabriel Ozorowski, Jonathan L. Torres, Celia LaBranche, David C. Montefiori, Rajesh P. Ringe, Marit J. van Gils, John P. Moore, Per Johan Klasse, Max Crispin, Neil P. King, Andrew B. Ward, Rogier W. Sanders
Publié 2021

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

par Philip J. M. Brouwer, Aleksandar Antanasijevic, Zachary Berndsen, Anila Yasmeen, Brooke Fiala, Tom P. L. Bijl, Ilja Bontjer, Jacob B. Bale, William Sheffler, Joel D. Allen, Anna Schorcht, Judith A. Burger, Miguel Camacho, Daniel Ellis, Christopher A. Cottrell, Anna-Janina Behrens, Marco Catalano, Iván del Moral-Sánchez, Thomas J. Ketas, Celia LaBranche, Marit J. van Gils, Kwinten Sliepen, Lance J. Stewart, Max Crispin, David C. Montefiori, David Baker, John P. Moore, Per Johan Klasse, Andrew B. Ward, Neil P. King, Rogier W. Sanders
Publié 2019

Cross-reactive antibodies after SARS-CoV-2 infection and vaccination

par Marloes Grobben, Karlijn van der Straten, Philip JM Brouwer, Mitch Brinkkemper, Pauline Maisonnasse, Nathalie Dereuddre-Bosquet, Brent Appelman, AH Ayesha Lavell, Lonneke A van Vught, Judith A Burger, Meliawati Poniman, Melissa Oomen, Dirk Eggink, Tom PL Bijl, Hugo DG van Willigen, Elke Wynberg, Bas J Verkaik, Orlane JA Figaroa, Peter J de Vries, Tessel M Boertien, Amsterdam UMC COVID-19 S3/HCW study group, Marije K Bomers, Jonne J Sikkens, Roger Le Grand, Menno D de Jong, Maria Prins, Amy W Chung, Godelieve J de Bree, Rogier W Sanders, Marit J van Gils
Publié 2021

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

par Kwinten Sliepen, Byung Woo Han, Ilja Bontjer, Petra Mooij, Fernando Garces, Anna-Janina Behrens, Kimmo Rantalainen, Sonu Kumar, Anita Sarkar, Philip J. M. Brouwer, Yuanzi Hua, Monica Tolazzi, Edith Schermer, Jonathan L. Torres, Gabriel Ozorowski, Patricia van der Woude, Alba Torrents de la Peña, Mariëlle J. van Breemen, Juan Miguel Camacho-Sánchez, Judith A. Burger, Max Medina-Ramírez, Nuria González, Jose Alcami, Celia LaBranche, Gabriella Scarlatti, Marit J. van Gils, Max Crispin, David C. Montefiori, Andrew B. Ward, Gerrit Koopman, John P. Moore, Robin J. Shattock, Willy M. Bogers, Ian A. Wilson, Rogier W. Sanders
Publié 2019