Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus

par Laurence Josset, Vineet D. Menachery, Lisa E. Gralinski, Sudhakar Agnihothram, Pavel Sova, Victoria S. Carter, Boyd L. Yount, Rachel L. Graham, Ralph S. Baric, Michael G. Katze
Publié 2013

Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles

par Jacob F. Kocher, Lisa C. Lindesmith, Kari Debbink, Anne Beall, Michael L. Mallory, Boyd L. Yount, Rachel L. Graham, Jeremy Huynh, J. Edward Gates, Eric F. Donaldson, Ralph S. Baric
Publié 2018

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.

par Lance D Eckerle, Michelle M Becker, Rebecca A Halpin, Kelvin Li, Eli Venter, Xiaotao Lu, Sana Scherbakova, Rachel L Graham, Ralph S Baric, Timothy B Stockwell, David J Spiro, Mark R Denison
Publié 2010

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

par Lisa C. Lindesmith, Michael L. Mallory, Kari Debbink, Eric F. Donaldson, Paul D. Brewer-Jensen, Excel W. Swann, Timothy P. Sheahan, Rachel L. Graham, Martina Beltramello, Davide Corti, Antonio Lanzavecchia, Ralph S. Baric
Publié 2018

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

par Adam S. Cockrell, Joshua C. Johnson, Ian N. Moore, David X. Liu, Kevin W. Bock, Madeline G. Douglas, Rachel L. Graham, Jeffrey Solomon, Lisa Torzewski, Christopher Bartos, Randy Hart, Ralph S. Baric, Reed F. Johnson
Publié 2018

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis

par Vineet D. Menachery, Lisa E. Gralinski, Hugh D. Mitchell, Kenneth H. Dinnon, Sarah R. Leist, Boyd L. Yount, Rachel L. Graham, Eileen T. McAnarney, Kelly G. Stratton, Adam S. Cockrell, Kari Debbink, Amy C. Sims, Katrina M. Waters, Ralph S. Baric
Publié 2017

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

par Vineet D. Menachery, Hugh D. Mitchell, Adam S. Cockrell, Lisa E. Gralinski, Boyd L. Yount, Rachel L. Graham, Eileen T. McAnarney, Madeline G. Douglas, Trevor Scobey, Anne Beall, Kenneth Dinnon, Jacob F. Kocher, Andrew E. Hale, Kelly G. Stratton, Katrina M. Waters, Ralph S. Baric
Publié 2017

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

par Maria L. Agostini, Erica L. Andres, Amy C. Sims, Rachel L. Graham, Timothy P. Sheahan, Xiaotao Lu, Everett Clinton Smith, James Brett Case, Joy Y. Feng, Robert Jordan, Adrian S. Ray, Tomas Cihlar, Dustin Siegel, Richard L. Mackman, Michael O. Clarke, Ralph S. Baric, Mark R. Denison
Publié 2018

A Mouse Model for <italic toggle="yes">Betacoronavirus</italic> Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

par Sudhakar Agnihothram, Boyd L. Yount, Eric F. Donaldson, Jeremy Huynh, Vineet D. Menachery, Lisa E. Gralinski, Rachel L. Graham, Michelle M. Becker, Sakshi Tomar, Trevor D. Scobey, Heather L. Osswald, Alan Whitmore, Robin Gopal, Arun K. Ghosh, Andrew Mesecar, Maria Zambon, Mark Heise, Mark R. Denison, Ralph S. Baric
Publié 2014