Reply to “Statins may decrease the Fatality Rate of MERS Infection”

por Allison L. Totura, Ralph S. Baric
Publicado 2015

Next-Generation High-Throughput Functional Annotation of Microbial Genomes

por Ralph S. Baric, Sean Crosson, Blossom Damania, Samuel I. Miller, Eric J. Rubin
Publicado 2016

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

por Courtney E. Comar, Stephen A. Goldstein, Yize Li, Boyd Yount, Ralph S. Baric, Susan R. Weiss
Publicado 2019

Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

por Allison L. Totura, Alan Whitmore, Sudhakar Agnihothram, Alexandra Schäfer, Michael G. Katze, Mark T. Heise, Ralph S. Baric
Publicado 2015

Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication

por Lily E. Adams, Kenneth H. Dinnon, Yixuan J. Hou, Timothy P. Sheahan, Mark T. Heise, Ralph S. Baric
Publicado 2021

Analysis of Individuals from a Dengue-Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type-Specific Epitopes

por Daniela V. Andrade, Leah C. Katzelnick, Doug G. Widman, Angel Balmaseda, Aravinda M. de Silva, Ralph S. Baric, Eva Harris
Publicado 2017

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

por Lisa E. Gralinski, Timothy P. Sheahan, Thomas E. Morrison, Vineet D. Menachery, Kara Jensen, Sarah R. Leist, Alan Whitmore, Mark T. Heise, Ralph S. Baric
Publicado 2018

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone

por Emily N. Gallichotte, Vineet D. Menachery, Boyd L. Yount, Douglas G. Widman, Kenneth H. Dinnon, Steven Hartman, Aravinda M. de Silva, Ralph S. Baric
Publicado 2017

Role of Zika Virus Envelope Protein Domain III as a Target of Human Neutralizing Antibodies

por Emily N. Gallichotte, Ellen F. Young, Thomas J. Baric, Boyd L. Yount, Stefan W. Metz, Matthew C. Begley, Aravinda M. de Silva, Ralph S. Baric
Publicado 2019

Cell Host Response to Infection with Novel Human Coronavirus EMC Predicts Potential Antivirals and Important Differences with SARS Coronavirus

por Laurence Josset, Vineet D. Menachery, Lisa E. Gralinski, Sudhakar Agnihothram, Pavel Sova, Victoria S. Carter, Boyd L. Yount, Rachel L. Graham, Ralph S. Baric, Michael G. Katze
Publicado 2013

Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation

por Joshua M. Thornbrough, Babal K. Jha, Boyd Yount, Stephen A. Goldstein, Yize Li, Ruth Elliott, Amy C. Sims, Ralph S. Baric, Robert H. Silverman, Susan R. Weiss
Publicado 2016

SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.

por Matthew B Frieman, Jun Chen, Thomas E Morrison, Alan Whitmore, William Funkhouser, Jerrold M Ward, Elaine W Lamirande, Anjeanette Roberts, Mark Heise, Kanta Subbarao, Ralph S Baric
Publicado 2010

Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles

por Jacob F. Kocher, Lisa C. Lindesmith, Kari Debbink, Anne Beall, Michael L. Mallory, Boyd L. Yount, Rachel L. Graham, Jeremy Huynh, J. Edward Gates, Eric F. Donaldson, Ralph S. Baric
Publicado 2018

Neutralization mechanism of a highly potent antibody against Zika virus

por Shuijun Zhang, Victor A. Kostyuchenko, Thiam-Seng Ng, Xin-Ni Lim, Justin S. G. Ooi, Sebastian Lambert, Ter Yong Tan, Douglas G. Widman, Jian Shi, Ralph S. Baric, Shee-Mei Lok
Publicado 2016

A Reverse Genetics Platform That Spans the Zika Virus Family Tree

por Douglas G. Widman, Ellen Young, Boyd L. Yount, Kenneth S. Plante, Emily N. Gallichotte, Derek L. Carbaugh, Kayla M. Peck, Jessica Plante, Jesica Swanstrom, Mark T. Heise, Helen M. Lazear, Ralph S. Baric
Publicado 2017

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.

por Lance D Eckerle, Michelle M Becker, Rebecca A Halpin, Kelvin Li, Eli Venter, Xiaotao Lu, Sana Scherbakova, Rachel L Graham, Ralph S Baric, Timothy B Stockwell, David J Spiro, Mark R Denison
Publicado 2010

A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans

por Usha K. Nivarthi, Jesica Swanstrom, Matthew J. Delacruz, Bhumi Patel, Anna P. Durbin, Steve S. Whitehead, Beth D. Kirkpatrick, Kristen K. Pierce, Sean A. Diehl, Leah Katzelnick, Ralph S. Baric, Aravinda M. de Silva
Publicado 2021

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

por Lisa C. Lindesmith, Michael L. Mallory, Kari Debbink, Eric F. Donaldson, Paul D. Brewer-Jensen, Excel W. Swann, Timothy P. Sheahan, Rachel L. Graham, Martina Beltramello, Davide Corti, Antonio Lanzavecchia, Ralph S. Baric
Publicado 2018

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

por Adam S. Cockrell, Joshua C. Johnson, Ian N. Moore, David X. Liu, Kevin W. Bock, Madeline G. Douglas, Rachel L. Graham, Jeffrey Solomon, Lisa Torzewski, Christopher Bartos, Randy Hart, Ralph S. Baric, Reed F. Johnson
Publicado 2018

Predicted norovirus resurgence in 2021–2022 due to the relaxation of nonpharmaceutical interventions associated with COVID-19 restrictions in England: a mathematical modeling study...

por Kathleen M. O’Reilly, Frank Sandman, David Allen, Christopher I. Jarvis, Amy Gimma, Amy Douglas, Lesley Larkin, Kerry L. M. Wong, Marc Baguelin, Ralph S. Baric, Lisa C. Lindesmith, Richard A. Goldstein, Judith Breuer, W. John Edmunds
Publicado 2021