BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

por Anne Margriet Heijink, Francien Talens, Lucas T. Jae, Stephanie E. van Gijn, Rudolf S. N. Fehrmann, Thijn R. Brummelkamp, Marcel A. T. M. van Vugt
Publicado 2019

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

por Lara M. Kleinfelter, Rohit K. Jangra, Lucas T. Jae, Andrew S. Herbert, Eva Mittler, Katie M. Stiles, Ariel S. Wirchnianski, Margaret Kielian, Thijn R. Brummelkamp, John M. Dye, Kartik Chandran
Publicado 2015

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

por Esther Ndungo, Andrew S. Herbert, Matthijs Raaben, Gregor Obernosterer, Rohan Biswas, Emily Happy Miller, Ariel S. Wirchnianski, Jan E. Carette, Thijn R. Brummelkamp, Sean P. Whelan, John M. Dye, Kartik Chandran
Publicado 2016

Niemann-Pick C1 Is Essential for Ebolavirus Replication and Pathogenesis <italic toggle="yes">In Vivo</italic>

por Andrew S. Herbert, Cristin Davidson, Ana I. Kuehne, Russell Bakken, Stephen Z. Braigen, Kathryn E. Gunn, Sean P. Whelan, Thijn R. Brummelkamp, Nancy A. Twenhafel, Kartik Chandran, Steven U. Walkley, John M. Dye
Publicado 2015

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.

por Marcel A T M van Vugt, Alexandra K Gardino, Rune Linding, Gerard J Ostheimer, H Christian Reinhardt, Shao-En Ong, Chris S Tan, Hua Miao, Susan M Keezer, Jeijin Li, Tony Pawson, Timothy A Lewis, Steven A Carr, Stephen J Smerdon, Thijn R Brummelkamp, Michael B Yaffe
Publicado 2010