α-2,3-Sialyltransferase Expression Level Impacts the Kinetics of Lipooligosaccharide Sialylation, Complement Resistance, and the Ability of <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> to Colonize the Murine Genital Tract
ABSTRACT Neisseria meningitidis and Neisseria gonorrhoeae modify the terminal lacto-N-neotetraose moiety of their lipooligosaccharide (LOS) with sialic acid. N. gonorrhoeae LOS sialylation blocks killing by complement, which is mediated at least in part by enhanced binding of the complement inhibit...
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Autores principales: | Lisa A. Lewis, Sunita Gulati, Elizabeth Burrowes, Bo Zheng, Sanjay Ram, Peter A. Rice |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
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Acceso en línea: | https://doaj.org/article/0dbc73670e9a4906bfb606cfedd54323 |
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