Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

The dearth of glioblastoma model systems that accurately recapitulate the disease remains a challenge. Here, the authors develop cancer avatars using genetically engineered human induced pluripotent cells.

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Auteurs principaux: Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Science
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Accès en ligne:https://doaj.org/article/129339bec1d846d6beb84462802c2cb9
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Internet

https://doaj.org/article/129339bec1d846d6beb84462802c2cb9

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