Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

The dearth of glioblastoma model systems that accurately recapitulate the disease remains a challenge. Here, the authors develop cancer avatars using genetically engineered human induced pluripotent cells.

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Autores principales:	Tomoyuki Koga, Isaac A. Chaim, Jorge A. Benitez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner, Kristen M. Turner, Florian M. Hessenauer, Matteo D’Antonio, Nam-phuong D. Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D. Boyer, John Ravits, Kelly A. Frazer, Vineet Bafna, Clark C. Chen, Paul S. Mischel, Gene W. Yeo, Frank B. Furnari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/129339bec1d846d6beb84462802c2cb9
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spelling	oai:doaj.org-article:129339bec1d846d6beb84462802c2cb92021-12-02T15:37:08ZLongitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells10.1038/s41467-020-14312-12041-1723https://doaj.org/article/129339bec1d846d6beb84462802c2cb92020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14312-1https://doaj.org/toc/2041-1723The dearth of glioblastoma model systems that accurately recapitulate the disease remains a challenge. Here, the authors develop cancer avatars using genetically engineered human induced pluripotent cells.Tomoyuki KogaIsaac A. ChaimJorge A. BenitezSebastian MarkmillerAlison D. ParisianRobert F. HevnerKristen M. TurnerFlorian M. HessenauerMatteo D’AntonioNam-phuong D. NguyenShahram SaberiJianhui MaShunichiro MikiAntonia D. BoyerJohn RavitsKelly A. FrazerVineet BafnaClark C. ChenPaul S. MischelGene W. YeoFrank B. FurnariNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tomoyuki Koga Isaac A. Chaim Jorge A. Benitez Sebastian Markmiller Alison D. Parisian Robert F. Hevner Kristen M. Turner Florian M. Hessenauer Matteo D’Antonio Nam-phuong D. Nguyen Shahram Saberi Jianhui Ma Shunichiro Miki Antonia D. Boyer John Ravits Kelly A. Frazer Vineet Bafna Clark C. Chen Paul S. Mischel Gene W. Yeo Frank B. Furnari Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
description	The dearth of glioblastoma model systems that accurately recapitulate the disease remains a challenge. Here, the authors develop cancer avatars using genetically engineered human induced pluripotent cells.
format	article
author	Tomoyuki Koga Isaac A. Chaim Jorge A. Benitez Sebastian Markmiller Alison D. Parisian Robert F. Hevner Kristen M. Turner Florian M. Hessenauer Matteo D’Antonio Nam-phuong D. Nguyen Shahram Saberi Jianhui Ma Shunichiro Miki Antonia D. Boyer John Ravits Kelly A. Frazer Vineet Bafna Clark C. Chen Paul S. Mischel Gene W. Yeo Frank B. Furnari
author_facet	Tomoyuki Koga Isaac A. Chaim Jorge A. Benitez Sebastian Markmiller Alison D. Parisian Robert F. Hevner Kristen M. Turner Florian M. Hessenauer Matteo D’Antonio Nam-phuong D. Nguyen Shahram Saberi Jianhui Ma Shunichiro Miki Antonia D. Boyer John Ravits Kelly A. Frazer Vineet Bafna Clark C. Chen Paul S. Mischel Gene W. Yeo Frank B. Furnari
author_sort	Tomoyuki Koga
title	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
title_short	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
title_full	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
title_fullStr	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
title_full_unstemmed	Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
title_sort	longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/129339bec1d846d6beb84462802c2cb9
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Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

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