Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance

ABSTRACT The World Health Organization reports that antibiotic-resistant pathogens represent an imminent global health disaster for the 21st century. Gram-positive superbugs threaten to breach last-line antibiotic treatment, and the pharmaceutical industry antibiotic development pipeline is waning....

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Autores principales: Lisa Bohlmann, David M. P. De Oliveira, Ibrahim M. El-Deeb, Erin B. Brazel, Nichaela Harbison-Price, Cheryl-lynn Y. Ong, Tania Rivera-Hernandez, Scott A. Ferguson, Amanda J. Cork, Minh-Duy Phan, Amelia T. Soderholm, Mark R. Davies, Graeme R. Nimmo, Gordon Dougan, Mark A. Schembri, Gregory M. Cook, Alastair G. McEwan, Mark von Itzstein, Christopher A. McDevitt, Mark J. Walker
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
Enterococcus faecium
Staphylococcus aureus
Streptococcus pyogenes
antibiotic resistance
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/16f22ff0c7c045db9913512c7d5962de
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https://doaj.org/article/16f22ff0c7c045db9913512c7d5962de

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