Viral Diversity Threshold for Adaptive Immunity in Prokaryotes
ABSTRACT Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas). CRISPR-Cas systems are genomic sensor...
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Main Authors: | Ariel D. Weinberger, Yuri I. Wolf, Alexander E. Lobkovsky, Michael S. Gilmore, Eugene V. Koonin |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2012
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Online Access: | https://doaj.org/article/356baaaeaa3f49c2814b91ecfb4b9ab5 |
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