Ten years of pathway analysis: current approaches and outstanding challenges.

Pathway analysis has become the first choice for gaining insight into the underlying biology of differentially expressed genes and proteins, as it reduces complexity and has increased explanatory power. We discuss the evolution of knowledge base-driven pathway analysis over its first decade, distinc...

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Bibliographic Details
Main Authors: Purvesh Khatri, Marina Sirota, Atul J Butte
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Online Access:https://doaj.org/article/5b956f7070b4449f94613a37ffe2718a
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