Diversification of Colonization Factors in a Multidrug-Resistant <named-content content-type="genus-species">Escherichia coli</named-content> Lineage Evolving under Negative Frequency-Dependent Selection

Diversification of Colonization Factors in a Multidrug-Resistant <named-content content-type="genus-species">Escherichia coli</named-content> Lineage Evolving under Negative Frequency-Dependent Selection

ABSTRACT Escherichia coli is a major cause of bloodstream and urinary tract infections globally. The wide dissemination of multidrug-resistant (MDR) strains of extraintestinal pathogenic E. coli (ExPEC) poses a rapidly increasing public health burden due to narrowed treatment options and increased r...

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Bibliographic Details
Main Authors: Alan McNally, Teemu Kallonen, Christopher Connor, Khalil Abudahab, David M. Aanensen, Carolyne Horner, Sharon J. Peacock, Julian Parkhill, Nicholas J. Croucher, Jukka Corander
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
AMR
Escherichia coli
evolutionary genomics
negative frequency-dependent selection
Microbiology
QR1-502
Online Access:https://doaj.org/article/6edd90209edf4b91aca6e2d94a4f76d2
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https://doaj.org/article/6edd90209edf4b91aca6e2d94a4f76d2

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