Functional annotation of rare gene aberration drivers of pancreatic cancer

Functional annotation of rare gene aberration drivers of pancreatic cancer

Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequently mutated in pancreatic cancer contribute to tumo...

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Auteurs principaux: Yiu Huen Tsang, Turgut Dogruluk, Philip M. Tedeschi, Joanna Wardwell-Ozgo, Hengyu Lu, Maribel Espitia, Nikitha Nair, Rosalba Minelli, Zechen Chong, Fengju Chen, Qing Edward Chang, Jennifer B. Dennison, Armel Dogruluk, Min Li, Haoqiang Ying, Joseph R. Bertino, Marie-Claude Gingras, Michael Ittmann, John Kerrigan, Ken Chen, Chad J. Creighton, Karina Eterovic, Gordon B. Mills, Kenneth L. Scott
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Science
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Accès en ligne:https://doaj.org/article/ad00a3ec62c944099c564237f8e7c498
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https://doaj.org/article/ad00a3ec62c944099c564237f8e7c498

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