TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

Background Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. Overcoming NK cell exhaustion would be an important step to allow them to fu...

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Autores principales: Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner
Formato: article
Lenguaje:EN
Publicado: BMJ Publishing Group 2021
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Acceso en línea:https://doaj.org/article/b8a8d841ff7e409c8d04b1a423e2c8fe
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