Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.

Unlike most bacterial species, Mycobacterium tuberculosis depends on the Clp proteolysis system for survival even in in vitro conditions. We hypothesized that Clp is required for the physiologic turnover of mycobacterial proteins whose accumulation is deleterious to bacterial growth and survival. To...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ravikiran M Raju, Mark P Jedrychowski, Jun-Rong Wei, Jessica T Pinkham, Annie S Park, Kathryn O'Brien, German Rehren, Dirk Schnappinger, Steven P Gygi, Eric J Rubin
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Accès en ligne:https://doaj.org/article/bdaac5ae17c84c90bb2fac362fa26bd5
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!