Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

por Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Publicado 2021

Unstable Mechanisms of Resistance to Inhibitors of <named-content content-type="genus-species">Escherichia coli</named-content> Lipoprotein Signal Peptidase

por Homer Pantua, Elizabeth Skippington, Marie-Gabrielle Braun, Cameron L. Noland, Jingyu Diao, Yutian Peng, Susan L. Gloor, Donghong Yan, Jing Kang, Anand Kumar Katakam, Janina Reeder, Georgette M. Castanedo, Keira Garland, Laszlo Komuves, Meredith Sagolla, Cary D. Austin, Jeremy Murray, Yiming Xu, Zora Modrusan, Min Xu, Emily J. Hanan, Sharookh B. Kapadia
Publicado 2020

βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells

por Peng Shang, Nadezda Stepicheva, Kenneth Teel, Austin McCauley, Christopher Scott Fitting, Stacey Hose, Rhonda Grebe, Meysam Yazdankhah, Sayan Ghosh, Haitao Liu, Anastasia Strizhakova, Joseph Weiss, Imran A. Bhutto, Gerard A. Lutty, Ashwath Jayagopal, Jiang Qian, José-Alain Sahel, J. Samuel Zigler, James T. Handa, Yuri Sergeev, Raju V. S. Rajala, Simon Watkins, Debasish Sinha
Publicado 2021

Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

por Q. Heydt, C. Xintaropoulou, A. Clear, M. Austin, I. Pislariu, F. Miraki-Moud, P. Cutillas, K. Korfi, M. Calaminici, W. Cawthorn, K. Suchacki, A. Nagano, J. G. Gribben, M. Smith, J. D. Cavenagh, H. Oakervee, A. Castleton, D. Taussig, B. Peck, A. Wilczynska, L. McNaughton, D. Bonnet, F. Mardakheh, B. Patel
Publicado 2021

New Medical Device and Therapeutic Approvals in Otolaryngology: State of the Art Review 2020

por Michael J. Brenner MD, Jared A. Shenson MD, Austin S. Rose MD, MBA, Tulio A. Valdez MD, MSc, Masayoshi Takashima MD, Omar G. Ahmed MD, Philip A. Weissbrod MD, Robert S. Hong MD, PhD, Hamid Djalilian MD, Jeffrey S. Wolf MD, Robert J. Morrison MD, Peter L. Santa Maria MBBS, PhD, Isaac D. Erbele MD
Publicado 2021

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

por Rebecca Pavlos, Elizabeth J. McKinnon, David A. Ostrov, Bjoern Peters, Soren Buus, David Koelle, Abha Chopra, Ryan Schutte, Craig Rive, Alec Redwood, Susana Restrepo, Austin Bracey, Thomas Kaever, Paisley Myers, Ellen Speers, Stacy A. Malaker, Jeffrey Shabanowitz, Yuan Jing, Silvana Gaudieri, Donald F. Hunt, Mary Carrington, David W. Haas, Simon Mallal, Elizabeth J. Phillips
Publicado 2017

Common workflows for computing material properties using different quantum engines

por Sebastiaan P. Huber, Emanuele Bosoni, Marnik Bercx, Jens Bröder, Augustin Degomme, Vladimir Dikan, Kristjan Eimre, Espen Flage-Larsen, Alberto Garcia, Luigi Genovese, Dominik Gresch, Conrad Johnston, Guido Petretto, Samuel Poncé, Gian-Marco Rignanese, Christopher J. Sewell, Berend Smit, Vasily Tseplyaev, Martin Uhrin, Daniel Wortmann, Aliaksandr V. Yakutovich, Austin Zadoks, Pezhman Zarabadi-Poor, Bonan Zhu, Nicola Marzari, Giovanni Pizzi
Publicado 2021

Multiple geographic origins of commensalism and complex dispersal history of Black Rats.

por Ken P Aplin, Hitoshi Suzuki, Alejandro A Chinen, R Terry Chesser, José Ten Have, Stephen C Donnellan, Jeremy Austin, Angela Frost, Jean Paul Gonzalez, Vincent Herbreteau, Francois Catzeflis, Julien Soubrier, Yin-Ping Fang, Judith Robins, Elizabeth Matisoo-Smith, Amanda D S Bastos, Ibnu Maryanto, Martua H Sinaga, Christiane Denys, Ronald A Van Den Bussche, Chris Conroy, Kevin Rowe, Alan Cooper
Publicado 2011

Mutations in topoisomerase IIβ result in a B cell immunodeficiency

por Lori Broderick, Shawn Yost, Dong Li, Matthew D. McGeough, Laela M. Booshehri, Marisela Guaderrama, Susannah D. Brydges, Karolina Kucharova, Niraj C. Patel, Margaret Harr, Hakon Hakonarson, Elaine Zackai, Ian G. Cowell, Caroline A. Austin, Boris Hügle, Corinna Gebauer, Jianguo Zhang, Xun Xu, Jian Wang, Ben A. Croker, Kelly A. Frazer, Christopher D. Putnam, Hal M. Hoffman
Publicado 2019

Key features of the environment promoting liver cancer in the absence of cirrhosis

por Marco Youssef William Zaki, Ahmed Khairallah Mahdi, Gillian Lucinda Patman, Anna Whitehead, João Pais Maurício, Misti Vanette McCain, Despina Televantou, Sameh Abou-Beih, Erik Ramon-Gil, Robyn Watson, Charlotte Cox, Jack Leslie, Caroline Wilson, Olivier Govaere, John Lunec, Derek Austin Mann, Sirintra Nakjang, Fiona Oakley, Ruchi Shukla, Quentin Mark Anstee, Dina Tiniakos, Helen Louise Reeves
Publicado 2021

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

por Iain W. McNae, James Kinkead, Divya Malik, Li-Hsuan Yen, Martin K. Walker, Chris Swain, Scott P. Webster, Nick Gray, Peter M. Fernandes, Elmarie Myburgh, Elizabeth A. Blackburn, Ryan Ritchie, Carol Austin, Martin A. Wear, Adrian J. Highton, Andrew J. Keats, Antonio Vong, Jacqueline Dornan, Jeremy C. Mottram, Paul A. M. Michels, Simon Pettit, Malcolm D. Walkinshaw
Publicado 2021

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of hepatocellular carcinoma

por Amaia Lujambio, Thomas Yau, Lipika Goyal, Andrew X Zhu, Ignacio Melero, Tim F Greten, Ann-Lii Cheng, Bruno Sangro, David J Pinato, Peter R Galle, Ghassan K Abou-Alfa, Austin G Duffy, Anthony B. El-Khoueiry, Richard S Finn, Aiwu Ruth He, Ahmed O Kaseb, Robin Kate Kelley, Riccardo Lencioni, Donna Mabry Hrones, Roberto I Troisi, Andrea Wilson Woods
Publicado 2021

Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury

por Abel Torres-Espín, Jenny Haefeli, Reza Ehsanian, Dolores Torres, Carlos A Almeida, J Russell Huie, Austin Chou, Dmitriy Morozov, Nicole Sanderson, Benjamin Dirlikov, Catherine G Suen, Jessica L Nielson, Nikos Kyritsis, Debra D Hemmerle, Jason F Talbott, Geoffrey T Manley, Sanjay S Dhall, William D Whetstone, Jacqueline C Bresnahan, Michael S Beattie, Stephen L McKenna, Jonathan Z Pan, Adam R Ferguson, The TRACK-SCI Investigators
Publicado 2021

Elucidating the fundamental fibrotic processes driving abdominal adhesion formation

por Deshka S. Foster, Clement D. Marshall, Gunsagar S. Gulati, Malini S. Chinta, Alan Nguyen, Ankit Salhotra, R. Ellen Jones, Austin Burcham, Tristan Lerbs, Lu Cui, Megan E. King, Ashley L. Titan, R. Chase Ransom, Anoop Manjunath, Michael S. Hu, Charles P. Blackshear, Shamik Mascharak, Alessandra L. Moore, Jeffrey A. Norton, Cindy J. Kin, Andrew A. Shelton, Michael Januszyk, Geoffrey C. Gurtner, Gerlinde Wernig, Michael T. Longaker
Publicado 2020

Phenological shifts in lake stratification under climate change

por R. Iestyn Woolway, Sapna Sharma, Gesa A. Weyhenmeyer, Andrey Debolskiy, Malgorzata Golub, Daniel Mercado-Bettín, Marjorie Perroud, Victor Stepanenko, Zeli Tan, Luke Grant, Robert Ladwig, Jorrit Mesman, Tadhg N. Moore, Tom Shatwell, Inne Vanderkelen, Jay A. Austin, Curtis L. DeGasperi, Martin Dokulil, Sofia La Fuente, Eleanor B. Mackay, S. Geoffrey Schladow, Shohei Watanabe, Rafael Marcé, Don C. Pierson, Wim Thiery, Eleanor Jennings
Publicado 2021

NOTCH1 is a mechanosensor in adult arteries

por Julia J. Mack, Thiago S. Mosqueiro, Brian J. Archer, William M. Jones, Hannah Sunshine, Guido C. Faas, Anais Briot, Raquel L. Aragón, Trent Su, Milagros C. Romay, Austin I. McDonald, Cheng-Hsiang Kuo, Carlos O. Lizama, Timothy F. Lane, Ann C. Zovein, Yun Fang, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim, Mohamad Navab, Alan M. Fogelman, Louis S. Bouchard, M. Luisa Iruela-Arispe
Publicado 2017

A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans.

por Rehan Qayyum, Beverly M Snively, Elad Ziv, Michael A Nalls, Yongmei Liu, Weihong Tang, Lisa R Yanek, Leslie Lange, Michele K Evans, Santhi Ganesh, Melissa A Austin, Guillaume Lettre, Diane M Becker, Alan B Zonderman, Andrew B Singleton, Tamara B Harris, Emile R Mohler, Benjamin A Logsdon, Charles Kooperberg, Aaron R Folsom, James G Wilson, Lewis C Becker, Alexander P Reiner
Publicado 2012

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

por Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publicado 2021

EMPress Enables Tree-Guided, Interactive, and Exploratory Analyses of Multi-omic Data Sets

por Kalen Cantrell, Marcus W. Fedarko, Gibraan Rahman, Daniel McDonald, Yimeng Yang, Thant Zaw, Antonio Gonzalez, Stefan Janssen, Mehrbod Estaki, Niina Haiminen, Kristen L. Beck, Qiyun Zhu, Erfan Sayyari, James T. Morton, George Armstrong, Anupriya Tripathi, Julia M. Gauglitz, Clarisse Marotz, Nathaniel L. Matteson, Cameron Martino, Jon G. Sanders, Anna Paola Carrieri, Se Jin Song, Austin D. Swafford, Pieter C. Dorrestein, Kristian G. Andersen, Laxmi Parida, Ho-Cheol Kim, Yoshiki Vázquez-Baeza, Rob Knight
Publicado 2021

Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors

por Matthew S. Dietz, Thomas L. Sutton, Brett S. Walker, Charles E. Gast, Luai Zarour, Sidharth K. Sengupta, John R. Swain, Jennifer Eng, Michael Parappilly, Kristen Limbach, Ariana Sattler, Erik Burlingame, Yuki Chin, Austin Gower, Jose L. Montoya Mira, Ajay Sapre, Yu-Jui Chiu, Daniel R. Clayburgh, SuEllen J. Pommier, Jeremy P. Cetnar, Jared M. Fischer, Jerry J. Jaboin, Rodney F. Pommier, Brett C. Sheppard, V. Liana Tsikitis, Alison H. Skalet, Skye C. Mayo, Charles D. Lopez, Joe W. Gray, Gordon B. Mills, Zahi Mitri, Young Hwan Chang, Koei Chin, Melissa H. Wong
Publicado 2021