SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms

por Ye Wang, Morvarid Mohseni, Angelo Grauel, Javier Estrada Diez, Wei Guan, Simon Liang, Jiyoung Elizabeth Choi, Minying Pu, Dongshu Chen, Tyler Laszewski, Stephanie Schwartz, Jane Gu, Leandra Mansur, Tyler Burks, Lauren Brodeur, Roberto Velazquez, Steve Kovats, Bhavesh Pant, Giri Buruzula, Emily Deng, Julie T. Chen, Farid Sari-Sarraf, Christina Dornelas, Malini Varadarajan, Haiyan Yu, Chen Liu, Joanne Lim, Huai-Xiang Hao, Xiaomo Jiang, Anthony Malamas, Matthew J. LaMarche, Felipe Correa Geyer, Margaret McLaughlin, Carlotta Costa, Joel Wagner, David Ruddy, Pushpa Jayaraman, Nathaniel D. Kirkpatrick, Pu Zhang, Oleg Iartchouk, Kimberly Aardalen, Viviana Cremasco, Glenn Dranoff, Jeffrey A. Engelman, Serena Silver, Hongyun Wang, William D. Hastings, Silvia Goldoni
Publicado 2021

Room temperature XFEL crystallography reveals asymmetry in the vicinity of the two phylloquinones in photosystem I

por Stephen M. Keable, Adrian Kölsch, Philipp S. Simon, Medhanjali Dasgupta, Ruchira Chatterjee, Senthil Kumar Subramanian, Rana Hussein, Mohamed Ibrahim, In-Sik Kim, Isabel Bogacz, Hiroki Makita, Cindy C. Pham, Franklin D. Fuller, Sheraz Gul, Daniel Paley, Louise Lassalle, Kyle D. Sutherlin, Asmit Bhowmick, Nigel W. Moriarty, Iris D. Young, Johannes P. Blaschke, Casper de Lichtenberg, Petko Chernev, Mun Hon Cheah, Sehan Park, Gisu Park, Jangwoo Kim, Sang Jae Lee, Jaehyun Park, Kensuke Tono, Shigeki Owada, Mark S. Hunter, Alexander Batyuk, Roland Oggenfuss, Mathias Sander, Serhane Zerdane, Dmitry Ozerov, Karol Nass, Henrik Lemke, Roman Mankowsky, Aaron S. Brewster, Johannes Messinger, Nicholas K. Sauter, Vittal K. Yachandra, Junko Yano, Athina Zouni, Jan Kern
Publicado 2021

First integrative trend analysis for a great ape species in Borneo

por Truly Santika, Marc Ancrenaz, Kerrie A. Wilson, Stephanie Spehar, Nicola Abram, Graham L. Banes, Gail Campbell-Smith, Lisa Curran, Laura d’Arcy, Roberto A. Delgado, Andi Erman, Benoit Goossens, Herlina Hartanto, Max Houghton, Simon J. Husson, Hjalmar S. Kühl, Isabelle Lackman, Ashley Leiman, Karmele Llano Sanchez, Niel Makinuddin, Andrew J. Marshall, Ari Meididit, Kerrie Mengersen, Musnanda, Nardiyono, Anton Nurcahyo, Kisar Odom, Adventus Panda, Didik Prasetyo, Purnomo, Andjar Rafiastanto, Slamet Raharjo, Dessy Ratnasari, Anne E. Russon, Adi H. Santana, Eddy Santoso, Iman Sapari, Jamartin Sihite, Ahmat Suyoko, Albertus Tjiu, Sri Suci Utami-Atmoko, Carel P. van Schaik, Maria Voigt, Jessie Wells, Serge A. Wich, Erik P. Willems, Erik Meijaard
Publicado 2017

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

por Charles Coutton, Alexandra S. Vargas, Amir Amiri-Yekta, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Pauline Le Tanno, Clémentine Wambergue-Legrand, Thomas Karaouzène, Guillaume Martinez, Serge Crouzy, Abbas Daneshipour, Seyedeh Hanieh Hosseini, Valérie Mitchell, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Jean-François Deleuze, Anne Boland, Sylviane Hennebicq, Véronique Satre, Pierre-Simon Jouk, Nicolas Thierry-Mieg, Beatrice Conne, Denis Dacheux, Nicolas Landrein, Alain Schmitt, Laurence Stouvenel, Patrick Lorès, Elma El Khouri, Serge P. Bottari, Julien Fauré, Jean-Philippe Wolf, Karin Pernet-Gallay, Jessica Escoffier, Hamid Gourabi, Derrick R. Robinson, Serge Nef, Emmanuel Dulioust, Raoudha Zouari, Mélanie Bonhivers, Aminata Touré, Christophe Arnoult, Pierre F. Ray
Publicado 2018

Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes

por Anna Esteve-Codina, Thomas P. Hofer, Dorothe Burggraf, Marion S. Heiss-Neumann, Wolfgang Gesierich, Anne Boland, Robert Olaso, Marie-Therese Bihoreau, Jean-Francois Deleuze, Winfried Moeller, Otmar Schmid, María Soler Artigas, Kathrin Renner, Jens M. Hohlfeld, Tobias Welte, Thomas Fuehner, Lukas Jerrentrup, Andreas Rembert Koczulla, Timm Greulich, Antje Prasse, Joachim Müller-Quernheim, Sumit Gupta, Christopher Brightling, Deepak R. Subramanian, David G. Parr, Umme Kolsum, Vandana Gupta, Imre Barta, Balázs Döme, János Strausz, Mariarita Stendardo, Marco Piattella, Piera Boschetto, Damian Korzybski, Dorota Gorecka, Adam Nowinski, Marc Dabad, Marcos Fernández-Callejo, David Endesfelder, Wolfgang zu Castell, Pieter S. Hiemstra, Per Venge, Elfriede Noessner, Thasso Griebel, Simon Heath, Dave Singh, Ivo Gut, Loems Ziegler-Heitbrock
Publicado 2021

Correction for Vangay et al., “Microbiome Metadata Standards: Report of the National Microbiome Data Collaborative’s Workshop and Follow-On Activities”

por Pajau Vangay, Josephine Burgin, Anjanette Johnston, Kristen L. Beck, Daniel C. Berrios, Kai Blumberg, Shane Canon, Patrick Chain, John-Marc Chandonia, Danielle Christianson, Sylvain V. Costes, Joan Damerow, William D. Duncan, Jose Pablo Dundore-Arias, Kjiersten Fagnan, Jonathan M. Galazka, Sean M. Gibbons, David Hays, Judson Hervey, Bin Hu, Bonnie L. Hurwitz, Pankaj Jaiswal, Marcin P. Joachimiak, Linda Kinkel, Joshua Ladau, Stanton L. Martin, Lee Ann McCue, Kayd Miller, Nigel Mouncey, Chris Mungall, Evangelos Pafilis, T. B. K. Reddy, Lorna Richardson, Simon Roux, Lynn M. Schriml, Justin P. Shaffer, Jagadish Chandrabose Sundaramurthi, Luke R. Thompson, Ruth E. Timme, Jie Zheng, Elisha M. Wood-Charlson, Emiley A. Eloe-Fadrosh
Publicado 2021

Levosimendan Efficacy and Safety: 20 years of SIMDAX in Clinical Use

por Zoltán Papp, Piergiuseppe Agostoni, Julian Alvarez, Dominique Bettex, Stefan Bouchez, Dulce Brito, Vladimir Černý, Josep Comin-Colet, Marisa G Crespo-Leiro, Juan F Delgado, Istvan Édes, Alexander A Eremenko, Dimitrios Farmakis, Francesco Fedele, Cândida Fonseca, Sonja Fruhwald, Massimo Girardis, Fabio Guarracino, Veli-Pekka Harjola, Matthias Heringlake, Antoine Herpain, Leo MA Heunks, Tryggve Husebye, Višnja Ivancan, Kristjan Karason, Sundeep Kaul, Matti Kivikko, Janek Kubica, Josep Masip, Simon Matskeplishvili, Alexandre Mebazaa, Markku S Nieminen, Fabrizio Oliva, Julius-Gyula Papp, John Parissis, Alexander Parkhomenko, Pentti Põder, Gerhard Pölzl, Alexander Reinecke, Sven-Erik Ricksten, Hynek Riha, Alain Rudiger, Toni Sarapohja, Robert HG Schwinger, Wolfgang Toller, Luigi Tritapepe, Carsten Tschöpe, Gerhard Wikström, Dirk von Lewinski, Bojan Vrtovec, Piero Pollesello
Publicado 2020

Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 - 2018.

por Sarah C Hill, Renato de Souza, Julien Thézé, Ingra Claro, Renato S Aguiar, Leandro Abade, Fabiana C P Santos, Mariana S Cunha, Juliana S Nogueira, Flavia C S Salles, Iray M Rocco, Adriana Y Maeda, Fernanda G S Vasami, Louis du Plessis, Paola P Silveira, Jaqueline G de Jesus, Joshua Quick, Natália C C A Fernandes, Juliana M Guerra, Rodrigo A Réssio, Marta Giovanetti, Luiz C J Alcantara, Cinthya S Cirqueira, Josué Díaz-Delgado, Fernando L L Macedo, Maria do Carmo S T Timenetsky, Regiane de Paula, Roberta Spinola, Juliana Telles de Deus, Luís F Mucci, Rosa Maria Tubaki, Regiane M T de Menezes, Patrícia L Ramos, Andre L de Abreu, Laura N Cruz, Nick Loman, Simon Dellicour, Oliver G Pybus, Ester C Sabino, Nuno R Faria
Publicado 2020

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases...

por Fiona M Blows, Kristy E Driver, Marjanka K Schmidt, Annegien Broeks, Flora E van Leeuwen, Jelle Wesseling, Maggie C Cheang, Karen Gelmon, Torsten O Nielsen, Carl Blomqvist, Päivi Heikkilä, Tuomas Heikkinen, Heli Nevanlinna, Lars A Akslen, Louis R Bégin, William D Foulkes, Fergus J Couch, Xianshu Wang, Vicky Cafourek, Janet E Olson, Laura Baglietto, Graham G Giles, Gianluca Severi, Catriona A McLean, Melissa C Southey, Emad Rakha, Andrew R Green, Ian O Ellis, Mark E Sherman, Jolanta Lissowska, William F Anderson, Angela Cox, Simon S Cross, Malcolm W R Reed, Elena Provenzano, Sarah-Jane Dawson, Alison M Dunning, Manjeet Humphreys, Douglas F Easton, Montserrat García-Closas, Carlos Caldas, Paul D Pharoah, David Huntsman
Publicado 2010

Prevalence of sexual dimorphism in mammalian phenotypic traits

por Natasha A. Karp, Jeremy Mason, Arthur L. Beaudet, Yoav Benjamini, Lynette Bower, Robert E. Braun, Steve D.M. Brown, Elissa J. Chesler, Mary E. Dickinson, Ann M. Flenniken, Helmut Fuchs, Martin Hrabe de Angelis, Xiang Gao, Shiying Guo, Simon Greenaway, Ruth Heller, Yann Herault, Monica J. Justice, Natalja Kurbatova, Christopher J. Lelliott, K.C. Kent Lloyd, Ann-Marie Mallon, Judith E. Mank, Hiroshi Masuya, Colin McKerlie, Terrence F. Meehan, Richard F. Mott, Stephen A. Murray, Helen Parkinson, Ramiro Ramirez-Solis, Luis Santos, John R. Seavitt, Damian Smedley, Tania Sorg, Anneliese O. Speak, Karen P. Steel, Karen L. Svenson, International Mouse Phenotyping Consortium, Shigeharu Wakana, David West, Sara Wells, Henrik Westerberg, Shay Yaacoby, Jacqueline K. White
Publicado 2017

Early cave art and ancient DNA record the origin of European bison

por Julien Soubrier, Graham Gower, Kefei Chen, Stephen M. Richards, Bastien Llamas, Kieren J. Mitchell, Simon Y. W. Ho, Pavel Kosintsev, Michael S. Y. Lee, Gennady Baryshnikov, Ruth Bollongino, Pere Bover, Joachim Burger, David Chivall, Evelyne Crégut-Bonnoure, Jared E. Decker, Vladimir B. Doronichev, Katerina Douka, Damien A. Fordham, Federica Fontana, Carole Fritz, Jan Glimmerveen, Liubov V. Golovanova, Colin Groves, Antonio Guerreschi, Wolfgang Haak, Tom Higham, Emilia Hofman-Kamińska, Alexander Immel, Marie-Anne Julien, Johannes Krause, Oleksandra Krotova, Frauke Langbein, Greger Larson, Adam Rohrlach, Amelie Scheu, Robert D. Schnabel, Jeremy F. Taylor, Małgorzata Tokarska, Gilles Tosello, Johannes van der Plicht, Ayla van Loenen, Jean-Denis Vigne, Oliver Wooley, Ludovic Orlando, Rafał Kowalczyk, Beth Shapiro, Alan Cooper
Publicado 2016

Protecting important sites for biodiversity contributes to meeting global conservation targets.

por Stuart H M Butchart, Jörn P W Scharlemann, Mike I Evans, Suhel Quader, Salvatore Aricò, Julius Arinaitwe, Mark Balman, Leon A Bennun, Bastian Bertzky, Charles Besançon, Timothy M Boucher, Thomas M Brooks, Ian J Burfield, Neil D Burgess, Simba Chan, Rob P Clay, Mike J Crosby, Nicholas C Davidson, Naamal De Silva, Christian Devenish, Guy C L Dutson, David F Día Z Fernández, Lincoln D C Fishpool, Claire Fitzgerald, Matt Foster, Melanie F Heath, Marc Hockings, Michael Hoffmann, David Knox, Frank W Larsen, John F Lamoreux, Colby Loucks, Ian May, James Millett, Dominic Molloy, Paul Morling, Mike Parr, Taylor H Ricketts, Nathalie Seddon, Benjamin Skolnik, Simon N Stuart, Amy Upgren, Stephen Woodley
Publicado 2012

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

por Bo Yang, Wei Zhou, Jiao Jiao, Jonas B. Nielsen, Michael R. Mathis, Mahyar Heydarpour, Guillaume Lettre, Lasse Folkersen, Siddharth Prakash, Claudia Schurmann, Lars Fritsche, Gregory A. Farnum, Maoxuan Lin, Mohammad Othman, Whitney Hornsby, Anisa Driscoll, Alexandra Levasseur, Marc Thomas, Linda Farhat, Marie-Pierre Dubé, Eric M. Isselbacher, Anders Franco-Cereceda, Dong-chuan Guo, Erwin P. Bottinger, G. Michael Deeb, Anna Booher, Sachin Kheterpal, Y. Eugene Chen, Hyun Min Kang, Jacob Kitzman, Heather J. Cordell, Bernard D. Keavney, Judith A. Goodship, Santhi K. Ganesh, Gonçalo Abecasis, Kim A. Eagle, Alan P. Boyle, Ruth J. F. Loos, Per Eriksson, Jean-Claude Tardif, Chad M. Brummett, Dianna M. Milewicz, Simon C. Body, Cristen J. Willer
Publicado 2017

State-of-the-art global models underestimate impacts from climate extremes

por Jacob Schewe, Simon N. Gosling, Christopher Reyer, Fang Zhao, Philippe Ciais, Joshua Elliott, Louis Francois, Veronika Huber, Heike K. Lotze, Sonia I. Seneviratne, Michelle T. H. van Vliet, Robert Vautard, Yoshihide Wada, Lutz Breuer, Matthias Büchner, David A. Carozza, Jinfeng Chang, Marta Coll, Delphine Deryng, Allard de Wit, Tyler D. Eddy, Christian Folberth, Katja Frieler, Andrew D. Friend, Dieter Gerten, Lukas Gudmundsson, Naota Hanasaki, Akihiko Ito, Nikolay Khabarov, Hyungjun Kim, Peter Lawrence, Catherine Morfopoulos, Christoph Müller, Hannes Müller Schmied, René Orth, Sebastian Ostberg, Yadu Pokhrel, Thomas A. M. Pugh, Gen Sakurai, Yusuke Satoh, Erwin Schmid, Tobias Stacke, Jeroen Steenbeek, Jörg Steinkamp, Qiuhong Tang, Hanqin Tian, Derek P. Tittensor, Jan Volkholz, Xuhui Wang, Lila Warszawski
Publicado 2019

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

por Amy H. Lee, Casey P. Shannon, Nelly Amenyogbe, Tue B. Bennike, Joann Diray-Arce, Olubukola T. Idoko, Erin E. Gill, Rym Ben-Othman, William S. Pomat, Simon D. van Haren, Kim-Anh Lê Cao, Momoudou Cox, Alansana Darboe, Reza Falsafi, Davide Ferrari, Daniel J. Harbeson, Daniel He, Cai Bing, Samuel J. Hinshaw, Jorjoh Ndure, Jainaba Njie-Jobe, Matthew A. Pettengill, Peter C. Richmond, Rebecca Ford, Gerard Saleu, Geraldine Masiria, John Paul Matlam, Wendy Kirarock, Elishia Roberts, Mehrnoush Malek, Guzmán Sanchez-Schmitz, Amrit Singh, Asimenia Angelidou, Kinga K. Smolen, The EPIC Consortium, Ryan R. Brinkman, Al Ozonoff, Robert E. W. Hancock, Anita H. J. van den Biggelaar, Hanno Steen, Scott J. Tebbutt, Beate Kampmann, Ofer Levy, Tobias R. Kollmann
Publicado 2019

Pulsed production of antihydrogen

por Claude Amsler, Massimiliano Antonello, Alexander Belov, Germano Bonomi, Roberto Sennen Brusa, Massimo Caccia, Antoine Camper, Ruggero Caravita, Fabrizio Castelli, Patrick Cheinet, Daniel Comparat, Giovanni Consolati, Andrea Demetrio, Lea Di Noto, Michael Doser, Mattia Fanì, Rafael Ferragut, Julian Fesel, Sebastian Gerber, Marco Giammarchi, Angela Gligorova, Lisa Theresa Glöggler, Francesco Guatieri, Stefan Haider, Alexander Hinterberger, Alban Kellerbauer, Olga Khalidova, Daniel Krasnický, Vittorio Lagomarsino, Chloé Malbrunot, Sebastiano Mariazzi, Viktor Matveev, Simon Müller, Giancarlo Nebbia, Patrick Nedelec, Lilian Nowak, Markus Oberthaler, Emmanuel Oswald, Davide Pagano, Luca Penasa, Vojtech Petracek, Luca Povolo, Francesco Prelz, Marco Prevedelli, Benjamin Rienäcker, Ole Røhne, Alberto Rotondi, Heidi Sandaker, Romualdo Santoro, Gemma Testera, Ingmari Tietje, Valerio Toso, Tim Wolz, Pauline Yzombard, Christian Zimmer, Nicola Zurlo
Publicado 2021

Etiological, epidemiological, and clinical features of acute diarrhea in China

por Li-Ping Wang, Shi-Xia Zhou, Xin Wang, Qing-Bin Lu, Lu-Sha Shi, Xiang Ren, Hai-Yang Zhang, Yi-Fei Wang, Sheng-Hong Lin, Cui-Hong Zhang, Meng-Jie Geng, Xiao-Ai Zhang, Jun Li, Shi-Wen Zhao, Zhi-Gang Yi, Xiao Chen, Zuo-Sen Yang, Lei Meng, Xin-Hua Wang, Ying-Le Liu, Ai-Li Cui, Sheng-Jie Lai, Meng-Yang Liu, Yu-Liang Zhu, Wen-Bo Xu, Yu Chen, Jian-Guo Wu, Zheng-Hong Yuan, Meng-Feng Li, Liu-Yu Huang, Zhong-Jie Li, Wei Liu, Li-Qun Fang, Huai-Qi Jing, Simon I. Hay, George F. Gao, Wei-Zhong Yang, The Chinese Centers for Disease Control and Prevention (CDC) Etiology of Diarrhea Surveillance Study Team
Publicado 2021

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling

por Nicolien A. van Vliet, Maxime M. Bos, Carisha S. Thesing, Layal Chaker, Maik Pietzner, Evelyn Houtman, Matt J. Neville, Ruifang Li-Gao, Stella Trompet, Rima Mustafa, Fariba Ahmadizar, Marian Beekman, Mariska Bot, Kathrin Budde, Constantinos Christodoulides, Abbas Dehghan, Christian Delles, Paul Elliott, Marina Evangelou, He Gao, Mohsen Ghanbari, Antonius E. van Herwaarden, M. Arfan Ikram, Martin Jaeger, J. Wouter Jukema, Ibrahim Karaman, Fredrik Karpe, Margreet Kloppenburg, Jennifer M. T. A. Meessen, Ingrid Meulenbelt, Yuri Milaneschi, Simon P. Mooijaart, Dennis O. Mook-Kanamori, Mihai G. Netea, Romana T. Netea-Maier, Robin P. Peeters, Brenda W. J. H. Penninx, Naveed Sattar, P. Eline Slagboom, H. Eka D. Suchiman, Henry Völzke, Ko Willems van Dijk, Raymond Noordam, Diana van Heemst, BBMRI Metabolomics Consortium
Publicado 2021

Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Coh...

por Jin Xu, Rebecca Green, Min Kim, Jodie Lord, Amera Ebshiana, Sarah Westwood, Alison L. Baird, Alejo J. Nevado-Holgado, Liu Shi, Abdul Hye, Stuart G. Snowden, Isabelle Bos, Stephanie J. B. Vos, Rik Vandenberghe, Charlotte E. Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen Elisa De Roeck, Sebastiaan Engelborghs, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans R. J. Verhey, Daniel Alcolea, Alberto Lleó, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Giovanni B. Frisoni, José Luis Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the European Medical Information Framework Consortium
Publicado 2021

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits.

por Benjamin F Voight, Hyun Min Kang, Jun Ding, Cameron D Palmer, Carlo Sidore, Peter S Chines, Noël P Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M Frayling, Iris M Heid, Anne U Jackson, Toby Johnson, Tuomas O Kilpeläinen, Cecilia M Lindgren, Andrew P Morris, Inga Prokopenko, Joshua C Randall, Richa Saxena, Nicole Soranzo, Elizabeth K Speliotes, Tanya M Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, N William Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J F Loos, Sekar Kathiresan, Patricia B Munroe, Christopher Newton-Cheh, Arne Pfeufer, Nilesh J Samani, Heribert Schunkert, Joel N Hirschhorn, David Altshuler, Mark I McCarthy, Gonçalo R Abecasis, Michael Boehnke
Publicado 2012