PathoNet introduced as a deep neural network backend for evaluation of Ki-67 and tumor-infiltrating lymphocytes in breast cancer

por Farzin Negahbani, Rasool Sabzi, Bita Pakniyat Jahromi, Dena Firouzabadi, Fateme Movahedi, Mahsa Kohandel Shirazi, Shayan Majidi, Amirreza Dehghanian
Publicado 2021

Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s

por Takaaki Oba, Mark D. Long, Tibor Keler, Henry C. Marsh, Hans Minderman, Scott I. Abrams, Song Liu, Fumito Ito
Publicado 2020

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

por L. Palanikumar, Laura Karpauskaite, Mohamed Al-Sayegh, Ibrahim Chehade, Maheen Alam, Sarah Hassan, Debabrata Maity, Liaqat Ali, Mona Kalmouni, Yamanappa Hunashal, Jemil Ahmed, Tatiana Houhou, Shake Karapetyan, Zackary Falls, Ram Samudrala, Renu Pasricha, Gennaro Esposito, Ahmed J. Afzal, Andrew D. Hamilton, Sunil Kumar, Mazin Magzoub
Publicado 2021

Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia

por Emmanuelle Supper, Saskia Rudat, Vivek Iyer, Alastair Droop, Kim Wong, Jean-François Spinella, Patrick Thomas, Guy Sauvageau, David J. Adams, Chi C. Wong
Publicado 2021

Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

por Xu Cao, Srinivasa Rao Allu, Shudong Jiang, Mengyu Jia, Jason R. Gunn, Cuiping Yao, Ethan P. LaRochelle, Jennifer R. Shell, Petr Bruza, David J. Gladstone, Lesley A. Jarvis, Jie Tian, Sergei A. Vinogradov, Brian W. Pogue
Publicado 2020

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

por Li-Yan Li, Qian Yang, Yan-Yi Jiang, Wei Yang, Yuan Jiang, Xiang Li, Masaharu Hazawa, Bo Zhou, Guo-Wei Huang, Xiu-E Xu, Sigal Gery, Ying Zhang, Ling-Wen Ding, Allen S. Ho, Zachary S. Zumsteg, Ming-Rong Wang, Melissa J. Fullwood, Stephen J. Freedland, Stephen J. Meltzer, Li-Yan Xu, En-Min Li, H. Phillip Koeffler, De-Chen Lin
Publicado 2021

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

por Yuying Liu, Xiaoyu Liang, Xiaonan Yin, Jiadi Lv, Ke Tang, Jingwei Ma, Tiantian Ji, Huafeng Zhang, Wenqian Dong, Xun Jin, Degao Chen, Yanchun Li, Songyan Zhang, Heidi Q. Xie, Bin Zhao, Tong Zhao, Jinzhi Lu, Zhuo-Wei Hu, Xuetao Cao, F. Xiao-Feng Qin, Bo Huang
Publicado 2017

Cooperation between oncogenic Ras and wild-type p53 stimulates STAT non-cell autonomously to promote tumor radioresistance

por Yong-Li Dong, Gangadhara P. Vadla, Jin-Yu (Jim) Lu, Vakil Ahmad, Thomas J. Klein, Lu-Fang Liu, Peter M. Glazer, Tian Xu, Chiswili-Yves Chabu
Publicado 2021

Publisher Correction: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

por Katherine A. Michaelis, Mason A. Norgard, Xinxia Zhu, Peter R. Levasseur, Shamilene Sivagnanam, Shannon M. Liudahl, Kevin G. Burfeind, Brennan Olson, Katherine R. Pelz, Diana M. Angeles Ramos, H. Carlo Maurer, Kenneth P. Olive, Lisa M. Coussens, Terry K. Morgan, Daniel L. Marks
Publicado 2019

ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor

por Sebastian Y. F. Michels, Andreas H. Scheel, Thomas Wündisch, Johannes M. Heuckmann, Roopika Menon, Michael Puesken, Carsten Kobe, Helen Pasternack, Carina Heydt, Matthias Scheffler, Rieke Fischer, Anne M. Schultheis, Sabine Merkelbach-Bruse, Lukas Heukamp, Reinhard Büttner, Jürgen Wolf
Publicado 2017

Prognostic Value of Gastrokine-2 (GKN2) and Its Correlation with Tumor-Infiltrating Immune Cells in Lung Cancer and Gastric Cancers

por Liu F, Wu H
Publicado 2020

Nanoparticles of a New Small-Molecule P-Selectin Inhibitor Attenuate Thrombosis, Inflammation, and Tumor Growth in Two Animal Models

por Feng Q, Wang M, Muhtar E, Wang Y, Zhu H
Publicado 2021

Automated tumor proportion score analysis for PD-L1 (22C3) expression in lung squamous cell carcinoma

por Jingxin Liu, Qiang Zheng, Xiao Mu, Yanfei Zuo, Bo Xu, Yan Jin, Yue Wang, Hua Tian, Yongguo Yang, Qianqian Xue, Ziling Huang, Lijun Chen, Bin Gu, Xianxu Hou, Linlin Shen, Yan Guo, Yuan Li
Publicado 2021

Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

por Raul Caso, James G. Connolly, Jian Zhou, Kay See Tan, James J. Choi, Gregory D. Jones, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Bastien Nguyen, Gaetano Rocco, Daniela Molena, Smita Sihag, Prasad S. Adusumilli, Matthew J. Bott, David R. Jones
Publicado 2021

High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients

por Maria Jenvin Stoen, S. Andersen, M. Rakaee, M. I. Pedersen, L. M. Ingebriktsen, R. M. Bremnes, T. Donnem, A. P. G. Lombardi, T. K. Kilvaer, L. T. Busund, E. Richardsen
Publicado 2021

Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates

por Daniel Y. Joh, Jacob T. Heggestad, Shengwei Zhang, Grace R. Anderson, Jayanta Bhattacharyya, Suzanne E. Wardell, Simone A. Wall, Amy B. Cheng, Faris Albarghouthi, Jason Liu, Sachi Oshima, Angus M. Hucknall, Terry Hyslop, Allison H. S. Hall, Kris C. Wood, E. Shelley Hwang, Kyle C. Strickland, Qingshan Wei, Ashutosh Chilkoti
Publicado 2021

Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity

por Wooseok Seo, Kanako Shimizu, Satoshi Kojo, Arinze Okeke, Terumi Kohwi-Shigematsu, Shin-ichiro Fujii, Ichiro Taniuchi
Publicado 2020

Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling

por Michael C. Brown, Mubeen M. Mosaheb, Malte Mohme, Zachary P. McKay, Eda K. Holl, Jonathan P. Kastan, Yuanfan Yang, Georgia M. Beasley, E. Shelley Hwang, David M. Ashley, Darell D. Bigner, Smita K. Nair, Matthias Gromeier
Publicado 2021

Elastin-specific MRI of extracellular matrix-remodelling following hepatic radiofrequency-ablation in a VX2 liver tumor model

por Federico Collettini, Carolin Reimann, Julia Brangsch, Julius Chapiro, Lynn Jeanette Savic, David C. Onthank, Simon P. Robinson, Uwe Karst, Rebecca Buchholz, Sarah Keller, Bernd Hamm, S. Nahum Goldberg, Marcus R. Makowski
Publicado 2021

Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

por Jason J. Zoeller, Roderick T. Bronson, Laura M. Selfors, Gordon B. Mills, Joan S. Brugge
Publicado 2017