Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa

por Laura Bricio-Moreno, Victoria H. Sheridan, Ian Goodhead, Stuart Armstrong, Janet K.L. Wong, Elaine M. Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E. Griswold, Craig Winstanley, Joanne L. Fothergill, Aras Kadioglu, Daniel R. Neill
Publicado 2018

Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge

por Henry R. Maun, Rajesh Vij, Benjamin T. Walters, Ashley Morando, Janet K. Jackman, Ping Wu, Alberto Estevez, Xiaocheng Chen, Yvonne Franke, Michael T. Lipari, Mark S. Dennis, Daniel Kirchhofer, Claudio Ciferri, Kelly M. Loyet, Tangsheng Yi, Charles Eigenbrot, Robert A. Lazarus, James T. Koerber
Publicado 2020

Structure of the poly-C9 component of the complement membrane attack complex

por Natalya V. Dudkina, Bradley A. Spicer, Cyril F. Reboul, Paul J. Conroy, Natalya Lukoyanova, Hans Elmlund, Ruby H. P. Law, Susan M. Ekkel, Stephanie C. Kondos, Robert J. A. Goode, Georg Ramm, James C. Whisstock, Helen R. Saibil, Michelle A. Dunstone
Publicado 2016

Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis

por Yanxiang Meng, Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Christopher R. Horne, Cindy Luo, Jean-Marc Garnier, Lung-Yu Liang, Angus D. Cowan, Andre L. Samson, Guillaume Lessene, Jarrod J. Sandow, Peter E. Czabotar, James M. Murphy
Publicado 2021

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

por Stephanie J. Alexopoulos, Sing-Young Chen, Amanda E. Brandon, Joseph M. Salamoun, Frances L. Byrne, Christopher J. Garcia, Martina Beretta, Ellen M. Olzomer, Divya P. Shah, Ashleigh M. Philp, Stefan R. Hargett, Robert T. Lawrence, Brendan Lee, James Sligar, Pascal Carrive, Simon P. Tucker, Andrew Philp, Carolin Lackner, Nigel Turner, Gregory J. Cooney, Webster L. Santos, Kyle L. Hoehn
Publicado 2020

Rare t(X;14)(q28;q32) translocation reveals link between MTCP1 and chronic lymphocytic leukemia

por Janek S. Walker, Zachary A. Hing, Steven Sher, James Cronin, Katie Williams, Bonnie Harrington, Jordan N. Skinner, Casey B. Cempre, Charles T. Gregory, Alexander Pan, Max Yano, Larry P. Beaver, Brandi R. Walker, Jadwiga M. Labanowska, Nyla A. Heerema, Krzysztof Mrózek, Jennifer A. Woyach, Amy S. Ruppert, Amy Lehman, Hatice Gulcin Ozer, Vincenzo Coppola, Pearlly Yan, John C. Byrd, James S. Blachly, Rosa Lapalombella
Publicado 2021

Stabilized coronavirus spike stem elicits a broadly protective antibody

por Ching-Lin Hsieh, Anne P. Werner, Sarah R. Leist, Laura J. Stevens, Ester Falconer, Jory A. Goldsmith, Chia-Wei Chou, Olubukola M. Abiona, Ande West, Kathryn Westendorf, Krithika Muthuraman, Ethan J. Fritch, Kenneth H. Dinnon, III, Alexandra Schäfer, Mark R. Denison, James D. Chappell, Ralph S. Baric, Barney S. Graham, Kizzmekia S. Corbett, Jason S. McLellan
Publicado 2021

Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors

por Katie L. Kunze, Patrick W. Johnson, Noud van Helmond, Jonathon W. Senefeld, Molly M. Petersen, Stephen A. Klassen, Chad C. Wiggins, Allan M. Klompas, Katelyn A. Bruno, John R. Mills, Elitza S. Theel, Matthew R. Buras, Michael A. Golafshar, Matthew A. Sexton, Juan C. Diaz Soto, Sarah E. Baker, John R. A. Shepherd, Nicole C. Verdun, Peter Marks, Nigel S. Paneth, DeLisa Fairweather, R. Scott Wright, Camille M. van Buskirk, Jeffrey L. Winters, James R. Stubbs, Katherine A. Senese, Michaela C. Pletsch, Zachary A. Buchholtz, Robert F. Rea, Vitaly Herasevich, Emily R. Whelan, Andrew J. Clayburn, Kathryn F. Larson, Juan G. Ripoll, Kylie J. Andersen, Elizabeth R. Lesser, Matthew N. P. Vogt, Joshua J. Dennis, Riley J. Regimbal, Philippe R. Bauer, Janis E. Blair, Arturo Casadevall, Rickey E. Carter, Michael J. Joyner
Publicado 2021

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

por Pradeep Natarajan, Gina M. Peloso, Seyedeh Maryam Zekavat, May Montasser, Andrea Ganna, Mark Chaffin, Amit V. Khera, Wei Zhou, Jonathan M. Bloom, Jesse M. Engreitz, Jason Ernst, Jeffrey R. O’Connell, Sanni E. Ruotsalainen, Maris Alver, Ani Manichaikul, W. Craig Johnson, James A. Perry, Timothy Poterba, Cotton Seed, Ida L. Surakka, Tonu Esko, Samuli Ripatti, Veikko Salomaa, Adolfo Correa, Ramachandran S. Vasan, Manolis Kellis, Benjamin M. Neale, Eric S. Lander, Goncalo Abecasis, Braxton Mitchell, Stephen S. Rich, James G. Wilson, L. Adrienne Cupples, Jerome I. Rotter, Cristen J. Willer, Sekar Kathiresan, NHLBI TOPMed Lipids Working Group
Publicado 2018

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

por Sarah E. Garnish, Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, Eric Denbaum, Annette V. Jacobsen, Wayland Yeung, Andre L. Samson, Christopher R. Horne, Cheree Fitzgibbon, Samuel N. Young, Phoebe P. C. Smith, Andrew I. Webb, Emma J. Petrie, Joanne M. Hildebrand, Natarajan Kannan, Peter E. Czabotar, Shohei Koide, James M. Murphy
Publicado 2021

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity

por J. Stephen, H. E. Scales, R. A. Benson, D. Erben, P. Garside, J. M. Brewer
Publicado 2017

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens

por Senjuti Saha, Akshaya Ramesh, Katrina Kalantar, Roly Malaker, Md Hasanuzzaman, Lillian M. Khan, Madeline Y. Mayday, M. S. I. Sajib, Lucy M. Li, Charles Langelier, Hafizur Rahman, Emily D. Crawford, Cristina M. Tato, Maksuda Islam, Yun-Fang Juan, Charles de Bourcy, Boris Dimitrov, James Wang, Jennifer Tang, Jonathan Sheu, Rebecca Egger, Tiago Rodrigues De Carvalho, Michael R. Wilson, Samir K. Saha, Joseph L. DeRisi
Publicado 2019

Determination of freedom-from-rabies for small Indian mongoose populations in the United States Virgin Islands, 2019-2020.

por A Springer Browne, Hannah M Cranford, Clint N Morgan, James A Ellison, Are Berentsen, Nicholas Wiese, Alexandra Medley, John Rossow, Leanne Jankelunas, Alan S McKinley, Claudia D Lombard, Nicole F Angeli, Thomas Kelley, Jennifer Valiulus, Bethany Bradford, Valicia J Burke-France, Cosme J Harrison, Irene Guendel, Marissa Taylor, Gerard L Blanchard, Jeffrey B Doty, David J Worthington, David Horner, Keith R Garcia, Joseph Roth, Brett R Ellis, Kristine M Bisgard, Ryan Wallace, Esther M Ellis
Publicado 2021

Genome analyses of an aggressive and invasive lineage of the Irish potato famine pathogen.

por David E L Cooke, Liliana M Cano, Sylvain Raffaele, Ruairidh A Bain, Louise R Cooke, Graham J Etherington, Kenneth L Deahl, Rhys A Farrer, Eleanor M Gilroy, Erica M Goss, Niklaus J Grünwald, Ingo Hein, Daniel MacLean, James W McNicol, Eva Randall, Ricardo F Oliva, Mathieu A Pel, David S Shaw, Julie N Squires, Moray C Taylor, Vivianne G A A Vleeshouwers, Paul R J Birch, Alison K Lees, Sophien Kamoun
Publicado 2012

Isolation of genetically diverse Marburg viruses from Egyptian fruit bats.

por Jonathan S Towner, Brian R Amman, Tara K Sealy, Serena A Reeder Carroll, James A Comer, Alan Kemp, Robert Swanepoel, Christopher D Paddock, Stephen Balinandi, Marina L Khristova, Pierre B H Formenty, Cesar G Albarino, David M Miller, Zachary D Reed, John T Kayiwa, James N Mills, Deborah L Cannon, Patricia W Greer, Emmanuel Byaruhanga, Eileen C Farnon, Patrick Atimnedi, Samuel Okware, Edward Katongole-Mbidde, Robert Downing, Jordan W Tappero, Sherif R Zaki, Thomas G Ksiazek, Stuart T Nichol, Pierre E Rollin
Publicado 2009

The Case for Adopting the “Species Complex” Nomenclature for the Etiologic Agents of Cryptococcosis

por Kyung J. Kwon-Chung, John E. Bennett, Brian L. Wickes, Wieland Meyer, Christina A. Cuomo, Kurt R. Wollenburg, Tihana A. Bicanic, Elizabeth Castañeda, Yun C. Chang, Jianghan Chen, Massimo Cogliati, Françoise Dromer, David Ellis, Scott G. Filler, Matthew C. Fisher, Thomas S. Harrison, Steven M. Holland, Shigeru Kohno, James W. Kronstad, Marcia Lazera, Stuart M. Levitz, Michail S. Lionakis, Robin C. May, Popchai Ngamskulrongroj, Peter G. Pappas, John R. Perfect, Volker Rickerts, Tania C. Sorrell, Thomas J. Walsh, Peter R. Williamson, Jianping Xu, Adrian M. Zelazny, Arturo Casadevall
Publicado 2017

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

por Liam B. King, Brandyn R. West, Crystal L. Moyer, Pavlo Gilchuk, Andrew Flyak, Philipp A. Ilinykh, Robin Bombardi, Sean Hui, Kai Huang, Alexander Bukreyev, James E. Crowe, Erica Ollmann Saphire
Publicado 2019

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

por Beth Lucas, Andrea J. White, Emilie J. Cosway, Sonia M. Parnell, Kieran D. James, Nick D. Jones, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Graham Anderson
Publicado 2020

Investigation of monogenic causes of familial breast cancer: data from the BEACCON case-control study

por Na Li, Belle W. X. Lim, Ella R. Thompson, Simone McInerny, Magnus Zethoven, Dane Cheasley, Simone M. Rowley, Michelle W. Wong-Brown, Lisa Devereux, Kylie L. Gorringe, Erica K. Sloan, Alison Trainer, Rodney J. Scott, Paul A. James, Ian G. Campbell
Publicado 2021

Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity

por J. G. Coen van Hasselt, Rayees Rahman, Jens Hansen, Alan Stern, Jaehee V. Shim, Yuguang Xiong, Amanda Pickard, Gomathi Jayaraman, Bin Hu, Milind Mahajan, James M. Gallo, Joseph Goldfarb, Eric A. Sobie, Marc R. Birtwistle, Avner Schlessinger, Evren U. Azeloglu, Ravi Iyengar
Publicado 2020