Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics
Abstract The tamoxifen-inducible Cre system is a popular transgenic method for controlling the induction of recombination by Cre at a specific time and in a specific cell type. However, tamoxifen is not an inert inducer of recombination, but an established endocrine disruptor with mixed agonist/anta...
Guardado en:
Autores principales: | Saloni H. Patel, Laura O’Hara, Nina Atanassova, Sarah E. Smith, Michael K. Curley, Diane Rebourcet, Annalucia L. Darbey, Anne-Louise Gannon, Richard M. Sharpe, Lee B. Smith |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/01bc0ff80d6349639fcb5b2646820108 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
CYP2D6 polymorphisms may predict occurrence of adverse effects to tamoxifen: a preliminary retrospective study
por: Wickramage I, et al.
Publicado: (2017) -
Biocompatible Nanomaterials as an Emerging Technology in Reproductive Health; a Focus on the Male
por: Barbara Fraser, et al.
Publicado: (2021) -
Potential adverse effects of nanoparticles on the reproductive system
por: Wang R, et al.
Publicado: (2018) -
Inhaled sphingosine has no adverse side effects in isolated ventilated and perfused pig lungs
por: Henning Carstens, et al.
Publicado: (2021) -
Tamoxifen for women at high risk of breast cancer
por: Nazarali SA, et al.
Publicado: (2014)