A multiscale approach to modelling drug metabolism by membrane-bound cytochrome P450 enzymes.
Cytochrome P450 enzymes are found in all life forms. P450s play an important role in drug metabolism, and have potential uses as biocatalysts. Human P450s are membrane-bound proteins. However, the interactions between P450s and their membrane environment are not well-understood. To date, all P450 cr...
Guardado en:
Autores principales: | Richard Lonsdale, Sarah L Rouse, Mark S P Sansom, Adrian J Mulholland |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/46b6511e53aa496abe4abdd625f84e3a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An electron transfer competent structural ensemble of membrane-bound cytochrome P450 1A1 and cytochrome P450 oxidoreductase
por: Goutam Mukherjee, et al.
Publicado: (2021) -
The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib
por: Katarína Vavrová, et al.
Publicado: (2022) -
Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
por: Tomas Laursen, et al.
Publicado: (2021) -
In vitro inhibitory effects of kaempferitrin on human liver cytochrome P450 enzymes
por: Ning Zhang, et al.
Publicado: (2019) -
Modulatory effects of Benjakul extract on rat hepatic cytochrome P450 enzymes
por: Suchittra Samuhasaneeto, et al.
Publicado: (2021)