TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer
Background Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. Overcoming NK cell exhaustion would be an important step to allow them to fu...
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Auteurs principaux: | Michael Conroy, John Kennedy, Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Caitriona Goggin, Colm MacEochagain, Sophie Lucas, David K Finlay, Clair M Gardiner |
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Format: | article |
Langue: | EN |
Publié: |
BMJ Publishing Group
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b8a8d841ff7e409c8d04b1a423e2c8fe |
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