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  1. 18281
    Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy
    “...Immune checkpoint inhibition (ICI) shows potential for cancer therapies, but response rates vary...”
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  2. 18282
    Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells
    “... responses in preclinical cancer models....”
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  3. 18283
    Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin
    “...Cutaneous squamous cell carcinoma (cSCC) is a skin cancer that normally progresses from UV-induced...”
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  4. 18284
    TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling
    “... the authors show that TSPAN15 promotes metastasis of oesophageal squamous cell cancer by enhancing BTRC...”
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  5. 18285
    EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance
    “...Ephrins are transmembrane proteins involved in cell-cell communication, and implicated in cancer...”
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  6. 18286
    Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
    “...IRE1/XBP-1 activation has a major role in Triple negative breast cancer (TNBC). Here, the authors...”
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  7. 18287
    Complex disease and phenotype mapping in the domestic dog
    “...The domestic dog is an important model organism for our understanding of cancer and other diseases...”
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  8. 18288
    Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance
    “... or cervical cancer....”
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  9. 18289
    p85β regulates autophagic degradation of AXL to activate oncogenic signaling
    “..., and therapeutically, p85β-expressing ovarian cancer cells are sensitive to AXL inhibition....”
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  10. 18290
    PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma
    “...The role of protein arginine methyltransferases (PRMTs) in epigenetic regulation in cancer is still...”
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  11. 18291
    Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability
    “... in cancer progression and metastasis. Here, the authors characterize a non-linear hysteretic response of E...”
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  12. 18292
    Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma
    “...Predicting the drug response of patients with cancer is crucial for implementing targeted therapy...”
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  13. 18293
    Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
    “...Neoantigens determine anti-cancer immunoreactivity and are important functional targets...”
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  14. 18294
    Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia
    “...Cancer cells under stress use acetate to maintain the acetyl-CoA pool and fuel lipid biosynthesis...”
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  15. 18295
    Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
    “...Mutations in BRCA1 are associated with an increased risk of breast and ovarian cancer. Here...”
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  16. 18296
    Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
    “...ARID1A, which is often mutated in human endometrial cancer, is a component of the SWI/SNF chromatin...”
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  17. 18297
    H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients
    “... in lesion-focused cancer precision medicine. Here the authors utilize mouse lymphoma genetics...”
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  18. 18298
    An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
    “... cancer spheroids and activated immune cells. They assess the effects of cortisol application...”
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  19. 18299
    Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry
    “... oncolytic activity correlate in 59 tested cancer cell lines....”
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  20. 18300
    Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses
    “... cancers. Here the authors show that inactivation of Wip1 in neutrophils promotes p53-dependent expression...”
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