Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

por Hyoung Kim, Haineng Xu, Erin George, Dorothy Hallberg, Sushil Kumar, Veena Jagannathan, Sergey Medvedev, Yasuto Kinose, Kyle Devins, Priyanka Verma, Kevin Ly, Yifan Wang, Roger A. Greenberg, Lauren Schwartz, Neil Johnson, Robert B. Scharpf, Gordon B. Mills, Rugang Zhang, Victor E. Velculescu, Eric J. Brown, Fiona Simpkins
Publicado 2020

Correction: Corrigendum: Diverse human extracellular RNAs are widely detected in human plasma

por Jane E. Freedman, Mark Gerstein, Eric Mick, Joel Rozowsky, Daniel Levy, Robert Kitchen, Saumya Das, Ravi Shah, Kirsty Danielson, Lea Beaulieu, Fabio C. P. Navarro, Yaoyu Wang, Timur R. Galeev, Alex Holman, Raymond Y. Kwong, Venkatesh Murthy, Selim E. Tanriverdi, Milka Koupenova, Ekaterina Mikhalev, Kahraman Tanriverdi
Publicado 2016

Rapid population decline in migratory shorebirds relying on Yellow Sea tidal mudflats as stopover sites

por Colin E. Studds, Bruce E. Kendall, Nicholas J. Murray, Howard B. Wilson, Danny I. Rogers, Robert S. Clemens, Ken Gosbell, Chris J. Hassell, Rosalind Jessop, David S. Melville, David A. Milton, Clive D. T. Minton, Hugh P. Possingham, Adrian C. Riegen, Phil Straw, Eric J. Woehler, Richard A. Fuller
Publicado 2017

Diverse human extracellular RNAs are widely detected in human plasma

por Jane E. Freedman, Mark Gerstein, Eric Mick, Joel Rozowsky, Daniel Levy, Robert Kitchen, Saumya Das, Ravi Shah, Kirsty Danielson, Lea Beaulieu, Fabio C. P. Navarro, Yaoyu Wang, Timur R. Galeev, Alex Holman, Raymond Y. Kwong, Venkatesh Murthy, Selim E. Tanriverdi, Milka Koupenova, Ekaterina Mikhalev, Kahraman Tanriverdi
Publicado 2016

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7

por Andreas Marg, Helena Escobar, Nikos Karaiskos, Stefanie A. Grunwald, Eric Metzler, Janine Kieshauer, Sascha Sauer, Diana Pasemann, Edoardo Malfatti, Dominique Mompoint, Susanna Quijano-Roy, Anastasiya Boltengagen, Joanna Schneider, Markus Schülke, Séverine Kunz, Robert Carlier, Carmen Birchmeier, Helge Amthor, Andreas Spuler, Christine Kocks, Nikolaus Rajewsky, Simone Spuler
Publicado 2019

Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man

por Joerg F. Hipp, Frederic Knoflach, Robert Comley, Theresa M. Ballard, Michael Honer, Gerhard Trube, Rodolfo Gasser, Eric Prinssen, Tanya L. Wallace, Andreas Rothfuss, Henner Knust, Sian Lennon-Chrimes, Michael Derks, Darren Bentley, Lisa Squassante, Stephane Nave, Jana Nöldeke, Christoph Wandel, Andrew W. Thomas, Maria-Clemencia Hernandez
Publicado 2021

An exome array study of the plasma metabolome

por Eugene P. Rhee, Qiong Yang, Bing Yu, Xuan Liu, Susan Cheng, Amy Deik, Kerry A. Pierce, Kevin Bullock, Jennifer E. Ho, Daniel Levy, Jose C. Florez, Sek Kathiresan, Martin G. Larson, Ramachandran S. Vasan, Clary B. Clish, Thomas J. Wang, Eric Boerwinkle, Christopher J. O’Donnell, Robert E. Gerszten
Publicado 2016

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

por Zhaohui Gu, Michelle Churchman, Kathryn Roberts, Yongjin Li, Yu Liu, Richard C. Harvey, Kelly McCastlain, Shalini C. Reshmi, Debbie Payne-Turner, Ilaria Iacobucci, Ying Shao, I-Ming Chen, Marcus Valentine, Deqing Pei, Karen L. Mungall, Andrew J. Mungall, Yussanne Ma, Richard Moore, Marco Marra, Eileen Stonerock, Julie M. Gastier-Foster, Meenakshi Devidas, Yunfeng Dai, Brent Wood, Michael Borowitz, Eric E. Larsen, Kelly Maloney, Leonard A. Mattano Jr, Anne Angiolillo, Wanda L. Salzer, Michael J. Burke, Francesca Gianni, Orietta Spinelli, Jerald P. Radich, Mark D. Minden, Anthony V. Moorman, Bella Patel, Adele K. Fielding, Jacob M. Rowe, Selina M. Luger, Ravi Bhatia, Ibrahim Aldoss, Stephen J. Forman, Jessica Kohlschmidt, Krzysztof Mrózek, Guido Marcucci, Clara D. Bloomfield, Wendy Stock, Steven Kornblau, Hagop M. Kantarjian, Marina Konopleva, Elisabeth Paietta, Cheryl L. Willman, Mignon L. Loh, Stephen P. Hunger, Charles G. Mullighan
Publicado 2016

The in vivo genetic program of murine primordial lung epithelial progenitors

por Laertis Ikonomou, Michael J. Herriges, Sara L. Lewandowski, Robert Marsland, Carlos Villacorta-Martin, Ignacio S. Caballero, David B. Frank, Reeti M. Sanghrajka, Keri Dame, Maciej M. Kańduła, Julia Hicks-Berthet, Matthew L. Lawton, Constantina Christodoulou, Attila J. Fabian, Eric Kolaczyk, Xaralabos Varelas, Edward E. Morrisey, John M. Shannon, Pankaj Mehta, Darrell N. Kotton
Publicado 2020

GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

por K. Saidas Nair, Chitrangda Srivastava, Robert V. Brown, Swanand Koli, Hélène Choquet, Hong Soon Kang, Yien-Ming Kuo, Sara A. Grimm, Caleb Sutherland, Alexandra Badea, G. Allan Johnson, Yin Zhao, Jie Yin, Kyoko Okamoto, Graham Clark, Terete Borrás, Gulab Zode, Krishnakumar Kizhatil, Subhabrata Chakrabarti, Simon W. M. John, Eric Jorgenson, Anton M. Jetten
Publicado 2021

Improved methods for marking active neuron populations

por Benjamien Moeyaert, Graham Holt, Rajtarun Madangopal, Alberto Perez-Alvarez, Brenna C. Fearey, Nicholas F. Trojanowski, Julia Ledderose, Timothy A. Zolnik, Aniruddha Das, Davina Patel, Timothy A. Brown, Robert N. S. Sachdev, Britta J. Eickholt, Matthew E. Larkum, Gina G. Turrigiano, Hod Dana, Christine E. Gee, Thomas G. Oertner, Bruce T. Hope, Eric R. Schreiter
Publicado 2018

Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

por Lucy I. Crouch, Marcelo V. Liberato, Paulina A. Urbanowicz, Arnaud Baslé, Christopher A. Lamb, Christopher J. Stewart, Katie Cooke, Mary Doona, Stephanie Needham, Richard R. Brady, Janet E. Berrington, Katarina Madunic, Manfred Wuhrer, Peter Chater, Jeffery P. Pearson, Robert Glowacki, Eric C. Martens, Fuming Zhang, Robert J. Linhardt, Daniel I. R. Spencer, David N. Bolam
Publicado 2020

Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

por Weiva Sieh, Joseph H. Rothstein, Robert J. Klein, Stacey E. Alexeeff, Lori C. Sakoda, Eric Jorgenson, Russell B. McBride, Rebecca E. Graff, Valerie McGuire, Ninah Achacoso, Luana Acton, Rhea Y. Liang, Jafi A. Lipson, Daniel L. Rubin, Martin J. Yaffe, Douglas F. Easton, Catherine Schaefer, Neil Risch, Alice S. Whittemore, Laurel A. Habel
Publicado 2020

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells

por Malika Arhatte, Gihan S. Gunaratne, Charbel El Boustany, Ivana Y. Kuo, Céline Moro, Fabrice Duprat, Magali Plaisant, Hélène Duval, Dahui Li, Nicolas Picard, Anais Couvreux, Christophe Duranton, Isabelle Rubera, Sophie Pagnotta, Sandra Lacas-Gervais, Barbara E. Ehrlich, Jonathan S. Marchant, Aaron M. Savage, Fredericus J. M. van Eeden, Robert N. Wilkinson, Sophie Demolombe, Eric Honoré, Amanda Patel
Publicado 2019

High seroprevalence of SARS-CoV-2 but low infection fatality ratio eight months after introduction in Nairobi, Kenya

por Isaac Ngere, Jeanette Dawa, Elizabeth Hunsperger, Nancy Otieno, Moses Masika, Patrick Amoth, Lyndah Makayotto, Carolyne Nasimiyu, Bronwyn M. Gunn, Bryan Nyawanda, Ouma Oluga, Carolyne Ngunu, Harriet Mirieri, John Gachohi, Doris Marwanga, Patrick K. Munywoki, Dennis Odhiambo, Moshe D. Alando, Robert F. Breiman, Omu Anzala, M. Kariuki Njenga, Marc Bulterys, Amy Herman-Roloff, Eric Osoro
Publicado 2021

Feasibility, safety, and acceptability of a remotely monitored exercise pilot CHAMP: A Clinical trial of High‐intensity Aerobic and resistance exercise for Metastatic castrate‐resi...

por Stacey A. Kenfield, Erin L. Van Blarigan, Neil Panchal, Alexander Bang, Li Zhang, Rebecca E. Graff, Yea‐Hung Chen, Charles J. Ryan, Anthony Luke, Robert U. Newton, Imelda Tenggara, Brooke Schultz, Elizabeth Wang, Emil Lavaki, Kyle Zuniga, Nicole Pinto, Hala Borno, Rahul Aggarwal, Terence Friedlander, Vadim S. Koshkin, Andrea Harzstark, Eric Small, June M. Chan
Publicado 2021

Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis

por Anne Piantadosi, Shibani S. Mukerji, Simon Ye, Michael J. Leone, Lisa M. Freimark, Daniel Park, Gordon Adams, Jacob Lemieux, Sanjat Kanjilal, Isaac H. Solomon, Asim A. Ahmed, Robert Goldstein, Vijay Ganesh, Bridget Ostrem, Kaelyn C. Cummins, Jesse M. Thon, Cormac M. Kinsella, Eric Rosenberg, Matthew P. Frosch, Marcia B. Goldberg, Tracey A. Cho, Pardis Sabeti
Publicado 2021

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

por Mylène Tajan, Marc Hennequart, Eric C. Cheung, Fabio Zani, Andreas K. Hock, Nathalie Legrave, Oliver D. K. Maddocks, Rachel A. Ridgway, Dimitris Athineos, Alejandro Suárez-Bonnet, Robert L. Ludwig, Laura Novellasdemunt, Nikolaos Angelis, Vivian S. W. Li, Georgios Vlachogiannis, Nicola Valeri, Nello Mainolfi, Vipin Suri, Adam Friedman, Mark Manfredi, Karen Blyth, Owen J. Sansom, Karen H. Vousden
Publicado 2021

Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria

por Elizabeth Ficko-Blean, Aurélie Préchoux, François Thomas, Tatiana Rochat, Robert Larocque, Yongtao Zhu, Mark Stam, Sabine Génicot, Murielle Jam, Alexandra Calteau, Benjamin Viart, David Ropartz, David Pérez-Pascual, Gaëlle Correc, Maria Matard-Mann, Keith A. Stubbs, Hélène Rogniaux, Alexandra Jeudy, Tristan Barbeyron, Claudine Médigue, Mirjam Czjzek, David Vallenet, Mark J. McBride, Eric Duchaud, Gurvan Michel
Publicado 2017

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

por Ignacio Sancho-Martinez, Emmanuel Nivet, Yun Xia, Tomoaki Hishida, Aitor Aguirre, Alejandro Ocampo, Li Ma, Robert Morey, Marie N. Krause, Andreas Zembrzycki, Olaf Ansorge, Eric Vazquez-Ferrer, Ilir Dubova, Pradeep Reddy, David Lam, Yuriko Hishida, Min-Zu Wu, Concepcion Rodriguez Esteban, Dennis O’Leary, Geoffrey M. Wahl, Inder M. Verma, Louise C. Laurent, Juan Carlos Izpisua Belmonte
Publicado 2016