Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements.
Ci-VSP contains a voltage-sensing domain (VSD) homologous to that of voltage-gated potassium channels. Using charge displacement ('gating' current) measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development...
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Autores principales: | Alicia Lundby, Hiroki Mutoh, Dimitar Dimitrov, Walther Akemann, Thomas Knöpfel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/dc6d0049eba54cd5aca726cf3bc19690 |
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