Five things to know about genetically modified (GM) insects for vector control.

por Luke Alphey, Nina Alphey
Publicado 2014

Sensing of the microbial neighborhood by Candida albicans.

por Emily M Mallick, Richard J Bennett
Publicado 2013

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

por Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng
Publicado 2014

The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity.

por Amit P Bhavsar, Nat F Brown, Jan Stoepel, Marcel Wiermer, Dale D O Martin, Karolynn J Hsu, Koshi Imami, Colin J Ross, Michael R Hayden, Leonard J Foster, Xin Li, Phil Hieter, B Brett Finlay
Publicado 2013

Transmission of equine influenza virus during an outbreak is characterized by frequent mixed infections and loose transmission bottlenecks.

por Joseph Hughes, Richard C Allen, Marc Baguelin, Katie Hampson, Gregory J Baillie, Debra Elton, J Richard Newton, Paul Kellam, James L N Wood, Edward C Holmes, Pablo R Murcia
Publicado 2012

Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.

por S Kyle Austin, Kimberly A Dowd, Bimmi Shrestha, Christopher A Nelson, Melissa A Edeling, Syd Johnson, Theodore C Pierson, Michael S Diamond, Daved H Fremont
Publicado 2012

Nodular inflammatory foci are sites of T cell priming and control of murine cytomegalovirus infection in the neonatal lung.

por Felix R Stahl, Katrin Heller, Stephan Halle, Kirsten A Keyser, Andreas Busche, Anja Marquardt, Karen Wagner, Jasmin Boelter, Yvonne Bischoff, Elisabeth Kremmer, Ramon Arens, Martin Messerle, Reinhold Förster
Publicado 2013

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65.

por Daniela S Silva, Daniela S Silva, Liliana M G Pereira, Ana R Moreira, Frederico Ferreira-da-Silva, Rui M Brito, Tiago Q Faria, Irene Zornetta, Cesare Montecucco, Pedro Oliveira, Jorge E Azevedo, Pedro J B Pereira, Sandra Macedo-Ribeiro, Ana do Vale, Nuno M S dos Santos
Publicado 2013

Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth.

por Megan K Murphy, Ling Yue, Ruimin Pan, Saikat Boliar, Anurag Sethi, Jianhui Tian, Katja Pfafferot, Etienne Karita, Susan A Allen, Emmanuel Cormier, Paul A Goepfert, Persephone Borrow, James E Robinson, S Gnanakaran, Eric Hunter, Xiang-Peng Kong, Cynthia A Derdeyn
Publicado 2013

Mycobacteriophages: windows into tuberculosis.

por Graham F Hatfull
Publicado 2014

HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon.

por Michael A Chattergoon, Rachel Latanich, Jeffrey Quinn, Matthew E Winter, Robert W Buckheit, Joel N Blankson, Drew Pardoll, Andrea L Cox
Publicado 2014

Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae.

por Fabrizio Lombardo, Yasmeen Ghani, Fotis C Kafatos, George K Christophides
Publicado 2013

MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice.

por Stuart Woods, Juliane Schroeder, Helen A McGachy, Robin Plevin, Craig W Roberts, James Alexander
Publicado 2013

Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.

por Hlumani Ndlovu, Mathew Darby, Monika Froelich, William Horsnell, Fred Lühder, Thomas Hünig, Frank Brombacher
Publicado 2014

Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replica...

por Melissa Z Mui, Michael Kucharski, Marie-Joëlle Miron, Woosuk Steve Hur, Albert M Berghuis, Paola Blanchette, Philip E Branton
Publicado 2013

A roadmap to the human virome.

por Eric Delwart
Publicado 2013

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

por Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M Walker, Birgitte B Simen, Elizabeth P St John, Po-Ying Chan-Hui, Kristine Swiderek, Steven H Kleinstein, Galit Alter, Michael S Seaman, Arup K Chakraborty, Daphne Koller, Ian A Wilson, George M Church, Dennis R Burton, Pascal Poignard
Publicado 2013

A heparan-dependent herpesvirus targets the olfactory neuroepithelium for host entry.

por Ricardo Milho, Bruno Frederico, Stacey Efstathiou, Philip G Stevenson
Publicado 2012

Sexuality generates diversity in the aflatoxin gene cluster: evidence on a global scale.

por Geromy G Moore, Jacalyn L Elliott, Rakhi Singh, Bruce W Horn, Joe W Dorner, Eric A Stone, Sofia N Chulze, German G Barros, Manjunath K Naik, Graeme C Wright, Kerstin Hell, Ignazio Carbone
Publicado 2013

Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity.

por Stephanie Ascough, Rebecca J Ingram, Karen K Chu, Catherine J Reynolds, Julie A Musson, Mehmet Doganay, Gökhan Metan, Yusuf Ozkul, Les Baillie, Shiranee Sriskandan, Stephen J Moore, Theresa B Gallagher, Hugh Dyson, E Diane Williamson, John H Robinson, Bernard Maillere, Rosemary J Boyton, Daniel M Altmann
Publicado 2014